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Protein

Ribonucleoside-diphosphate reductase

Gene

D623_10028667

Organism
Myotis brandtii (Brandt's bat)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.UniRule annotation

Catalytic activityi

2'-deoxyribonucleoside diphosphate + thioredoxin disulfide + H2O = ribonucleoside diphosphate + thioredoxin.UniRule annotation

Pathwayi: DNA replication

This protein is involved in the pathway DNA replication, which is part of Genetic information processing.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway DNA replication and in Genetic information processing.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotation
Biological processDNA replicationUniRule annotation
LigandATP-bindingPROSITE-ProRule annotation, Nucleotide-binding

Enzyme and pathway databases

UniPathwayiUPA00326

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonucleoside-diphosphate reductaseUniRule annotation (EC:1.17.4.1UniRule annotation)
Gene namesi
ORF Names:D623_10028667Imported
OrganismiMyotis brandtii (Brandt's bat)Imported
Taxonomic identifieri109478 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaChiropteraMicrochiropteraVespertilionidaeMyotis
Proteomesi
  • UP000052978 Componenti: Unassembled WGS sequence

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini13 – 103ATP-coneInterPro annotationAdd BLAST91

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili764 – 785Sequence analysisAdd BLAST22

Sequence similaritiesi

Belongs to the ribonucleoside diphosphate reductase large chain family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Family and domain databases

InterProiView protein in InterPro
IPR005144 ATP-cone_dom
IPR013346 NrdE_NrdA
IPR000788 RNR_lg_C
IPR013509 RNR_lsu_N
IPR008926 RNR_R1-su_N
PfamiView protein in Pfam
PF03477 ATP-cone, 1 hit
PF02867 Ribonuc_red_lgC, 1 hit
PF00317 Ribonuc_red_lgN, 1 hit
PRINTSiPR01183 RIBORDTASEM1
SUPFAMiSSF48168 SSF48168, 1 hit
TIGRFAMsiTIGR02506 NrdE_NrdA, 1 hit
PROSITEiView protein in PROSITE
PS51161 ATP_CONE, 1 hit
PS00089 RIBORED_LARGE, 1 hit

Sequencei

Sequence statusi: Complete.

S7MV87-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGARKSRGLA FSSAVTSHGR QERVMFDKIT SRIQKLCYGL NMDFVDPAQI
60 70 80 90 100
TMKVIQGLYS GVTTVELDTL AAETAATLTT KHPDYAILAA RIAVSNLHKE
110 120 130 140 150
TKKVFSDVME DLYNYINPHN GKHSPMVAQS TLDIVLANKD RLNSAIIYDR
160 170 180 190 200
DFSYNYFGFK TLERSYLLKI NGKVAERPQH MLMRVSVGIH EEDIDAAIET
210 220 230 240 250
YNLLSERWFT HASPTLFNAG TNRPQLSSCF LLSMKDDSIE GIYDTLKQCA
260 270 280 290 300
LISKSAGGIG VAVSCIRATG SYIAGTNGNS NGLVPMLRVY NNTARYVDQG
310 320 330 340 350
GNKRPGAFAI YLEPWHLDIF EFLDLKKNTG KEEQRARDLF FALWIPDLFM
360 370 380 390 400
KRVETNQDWS LMCPNECPGL DEVWGEEFEK LYESYEKQGR VRKVVKAQQL
410 420 430 440 450
WYAIIESQTE TGTPYMLYKD SCNRKSNQQN LGTIKCSNLC TEIVEYTSKD
460 470 480 490 500
EVAVCNLASL ALNMYVTSEH TYDFKKLAEV TKVVVRNLNK IIDINYYPIP
510 520 530 540 550
EAYLSNKRHR PIGIGVQGLA DAFILMRYPF ESPEAQLLNK QIFETIYYGA
560 570 580 590 600
LEASCDLAKE HGPYETYEGS PVSKGILQYD MWNVTPTDLW DWKLLKEKIA
610 620 630 640 650
KYGIRNSLLI APMPTASTAQ ILGNNESIEP YTSNIYTRRV LSGEFQIVNP
660 670 680 690 700
HLLKDLTERG LWNEEMKNQI IACNGSIQSI PEIPDDLKQL YKTVWEISQK
710 720 730 740 750
TILNMAAERG AFIDQSQSLN IHIAEPNYGK LTSMHFYGWK QGLKTGMYYL
760 770 780 790 800
RTRPAANPIQ FTLNKEKLKD KEKASKEEEE KERNTAAMVC SLENRDECLM

CGS
Length:803
Mass (Da):91,166
Last modified:October 16, 2013 - v1
Checksum:iB61ADFD68347DE41
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KE162454 Genomic DNA Translation: EPQ08369.1

Similar proteinsi

Entry informationi

Entry nameiS7MV87_MYOBR
AccessioniPrimary (citable) accession number: S7MV87
Entry historyiIntegrated into UniProtKB/TrEMBL: October 16, 2013
Last sequence update: October 16, 2013
Last modified: July 5, 2017
This is version 16 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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