Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Lysophospholipase NTE1

Gene

BN860_03202g

Organism
Zygosaccharomyces bailii (strain CLIB 213 / ATCC 58445 / CBS 680 / CCRC 21525 / NBRC 1098 / NCYC 1416 / NRRL Y-2227)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Intracellular phospholipase B that catalyzes the double deacylation of phosphatidylcholine (PC) to glycerophosphocholine (GroPCho). Plays an important role in membrane lipid homeostasis.UniRule annotation

Catalytic activityi

2-lysophosphatidylcholine + H2O = glycerophosphocholine + a carboxylate.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei1365NucleophilePROSITE-ProRule annotation1
Active sitei1483Proton acceptorPROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolasePROSITE-ProRule annotation
Biological processLipid degradationPROSITE-ProRule annotation, Lipid metabolism

Names & Taxonomyi

Protein namesi
Recommended name:
Lysophospholipase NTE1UniRule annotation (EC:3.1.1.5UniRule annotation)
Alternative name(s):
Intracellular phospholipase BUniRule annotation
Gene namesi
ORF Names:BN860_03202gImported
OrganismiZygosaccharomyces bailii (strain CLIB 213 / ATCC 58445 / CBS 680 / CCRC 21525 / NBRC 1098 / NCYC 1416 / NRRL Y-2227)Imported
Taxonomic identifieri1333698 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeZygosaccharomyces
Proteomesi
  • UP000019375 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei48 – 65HelicalUniRule annotationAdd BLAST18
Transmembranei71 – 87HelicalUniRule annotationAdd BLAST17
Transmembranei99 – 118HelicalUniRule annotationAdd BLAST20

Keywords - Cellular componenti

Endoplasmic reticulumUniRule annotation, Membrane

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini782 – 885Cyclic nucleotide-bindingInterPro annotationAdd BLAST104
Domaini899 – 1033Cyclic nucleotide-bindingInterPro annotationAdd BLAST135
Domaini1332 – 1496PNPLAInterPro annotationAdd BLAST165

Sequence similaritiesi

Belongs to the NTE family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

PhylomeDBiS6ELJ7.

Family and domain databases

CDDicd00038. CAP_ED. 2 hits.
Gene3Di2.60.120.10. 3 hits.
InterProiView protein in InterPro
IPR016035. Acyl_Trfase/lysoPLipase.
IPR018490. cNMP-bd-like.
IPR000595. cNMP-bd_dom.
IPR001423. LysoPLipase_patatin_CS.
IPR002641. PNPLA_dom.
IPR014710. RmlC-like_jellyroll.
PfamiView protein in Pfam
PF00027. cNMP_binding. 2 hits.
PF01734. Patatin. 1 hit.
SMARTiView protein in SMART
SM00100. cNMP. 2 hits.
SUPFAMiSSF51206. SSF51206. 4 hits.
SSF52151. SSF52151. 1 hit.
PROSITEiView protein in PROSITE
PS50042. CNMP_BINDING_3. 2 hits.
PS51635. PNPLA. 1 hit.
PS01237. UPF0028. 1 hit.

Sequencei

Sequence statusi: Complete.

S6ELJ7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNVSNQTKLI PLRGSDNAPG FVSSSQSSTQ RQMSQSGQQA ASSNSQGWLV
60 70 80 90 100
DNILNVTWVI SYFLIGSTRY FARWSIYMVT VCLLKVPKWC FLSANQFHLT
110 120 130 140 150
ISFPAFLALA TIFTYMVYCL MKDQVLSQYK TLSSDDVDSN EADTTHSSTN
160 170 180 190 200
GGISDQKDEK LGIRGQLRYG KREKDEESFA TSYLDQFLSA IRIFGYLEKP
210 220 230 240 250
VFHDLTKNMK TQKLDEGEIL LLDNSVGFSI VVEGTLQIYH KLEQDSDIVR
260 270 280 290 300
PNEAYKRKMD NITDKTEYGD RESLSSCANE FTAGSGNDFI DNEEENSSNY
310 320 330 340 350
IELKNGLGKF QLLNTVKSGN PVSSLVNILN LFTSSNVGDG WGLAAPSSLS
360 370 380 390 400
LNDKPIDFRS PFATQNDWNQ GSRGSNASNS PPPDLEKSVD GEPDLMQTYS
410 420 430 440 450
ETNDMPQGLM PKVIACASTD CTIAIIPPQA FAKLTAKYPR SASHIIQMIL
460 470 480 490 500
TRLYRVTFQT AHDYLGLTRE LIDMEVLLNN TVSYEIPFYL KETVMKKLKS
510 520 530 540 550
KSEKEDINES RMEKKKEQKV QNSVKKGPAR PKMAHLKHSQ SHFNSSSTNL
560 570 580 590 600
RSSRHVVLDS RDHFNPGDLL SSVPLLRKES LNPSTASSTQ ESKSSSPPAS
610 620 630 640 650
IPSSQRGVSS TSSKSSNKLL QKPPHSSAIL ADSSHNRNEP NSSHANLLVQ
660 670 680 690 700
REENIKDRSF SAAEEETEES AVKMALVEAM FTYLGINKEN MRFPSVVSSS
710 720 730 740 750
GTSDELTGTS HRSSSVSPDA TSSMSLSSYA SPSLTNGASY TSVLRILPSD
760 770 780 790 800
YAISSRRTKP RKKAEYKEEI SPKLTFESAK NDFAQGIKLQ FFKQGTTIVE
810 820 830 840 850
QNRKGKGLFY IISGKIAVTT GKGSRMASDE KSLNQEHPET LLYIVGAGGI
860 870 880 890 900
AGYLSSLIGY KSFVNLKAKT DCYVGFLSSQ ILERLCDKYF MMYLRITETL
910 920 930 940 950
TSLLSPRLLK LDHALEWIHL SASDTLFNQG DPANGIYVVL SGRLRQVQKT
960 970 980 990 1000
VSNQKGDETD PRGDDDEDLE ILGELAQGES FGEVEVLTAM NRFSSIIAVR
1010 1020 1030 1040 1050
DSELARIPRT LFELLALEYP SIMIRVSRLV ARKILASQKS GTNQPSKLAD
1060 1070 1080 1090 1100
GNGGKYDLNA TIPPTKATFG QRKHIHNSST GSITFRTIAI LPITSGLPVE
1110 1120 1130 1140 1150
AFAMKLVQAF KRVGRSTIGL NQRTALSHLG RHAFDRLAKL KESGYFAELE
1160 1170 1180 1190 1200
DMFQTVVYIA DTPVNSSWTK TCIAQGDCIL LLADATAFPE VGEYEKLLLK
1210 1220 1230 1240 1250
SRTTARTELI LLHPERYVEP GLTHRWLKHR TWVDSQHHVQ FAVNPLDTEA
1260 1270 1280 1290 1300
NPKHNGINIG AFSLVDRFIQ TEFSKKTQEN ISKLVPDAIK ARVENISSRF
1310 1320 1330 1340 1350
INRKRQVYTP VYSHKNDFLR LARILSGKAI GLVLGGGGAR GISHLGFLKA
1360 1370 1380 1390 1400
IEDQGIPIDM IGGTSIGAFV GGLYAKDYDL VPIYGRVKKF AGRISSIWRM
1410 1420 1430 1440 1450
VADLTWPVTS YTTGHEFNRG IWKTFGDVRI EDFWVQYYCN STNITESVQE
1460 1470 1480 1490 1500
IHSSGYAWRY IRASMSLAGL LPPLEDKGSM LLDGGYLDNL PVWEMKARGC
1510 1520 1530 1540 1550
DTIFAVDVGS VDDRTPMQYG DSLNGFWIVI NRWNPFSSHP NIPNMAEIQM
1560 1570 1580 1590 1600
RLGYVASVNA LEKAKQTSGV IYVRPPIEDY ATLDFSKFEE IYDVGADYGH
1610 1620 1630
TFINELIAQG KMPYIPGSQP KQEGESPEFF LRRRNSI
Length:1,637
Mass (Da):182,130
Last modified:October 16, 2013 - v1
Checksum:i3542AEE875539963
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HG316464 Genomic DNA. Translation: CDF91453.1.

Similar proteinsi

Entry informationi

Entry nameiS6ELJ7_ZYGB2
AccessioniPrimary (citable) accession number: S6ELJ7
Entry historyiIntegrated into UniProtKB/TrEMBL: October 16, 2013
Last sequence update: October 16, 2013
Last modified: October 25, 2017
This is version 20 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported