Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

S6AP25

- S6AP25_9PROT

UniProt

S6AP25 - S6AP25_9PROT

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Ribulose bisphosphate carboxylase

Gene

cbbM

Organism
Sulfuricella denitrificans skB26
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site.UniRule annotation

Catalytic activityi

2 3-phospho-D-glycerate + 2 H+ = D-ribulose 1,5-bisphosphate + CO2 + H2O.UniRule annotation
3-phospho-D-glycerate + 2-phosphoglycolate = D-ribulose 1,5-bisphosphate + O2.UniRule annotation

Cofactori

Binds 1 magnesium ion per subunit.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei111 – 1111Substrate; in homodimeric partnerUniRule annotation
Active sitei166 – 1661Proton acceptorUniRule annotation
Binding sitei168 – 1681SubstrateUniRule annotation
Metal bindingi191 – 1911Magnesium; via carbamate groupUniRule annotation
Metal bindingi193 – 1931MagnesiumUniRule annotation
Metal bindingi194 – 1941MagnesiumUniRule annotation
Active sitei287 – 2871Proton acceptorUniRule annotation
Binding sitei288 – 2881SubstrateUniRule annotation
Binding sitei321 – 3211SubstrateUniRule annotation
Sitei329 – 3291Transition state stabilizerUniRule annotation
Binding sitei368 – 3681SubstrateUniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. monooxygenase activity Source: UniProtKB-KW
  3. ribulose-bisphosphate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. reductive pentose-phosphate cycle Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationImported, MonooxygenaseUniRule annotation, Oxidoreductase

Keywords - Biological processi

Calvin cycleUniRule annotation, Carbon dioxide fixationUniRule annotation

Keywords - Ligandi

MagnesiumUniRule annotation, Metal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Ribulose bisphosphate carboxylaseUniRule annotation (EC:4.1.1.39UniRule annotation)
Short name:
RuBisCOUniRule annotation
Gene namesi
Name:cbbMUniRule annotationImported
ORF Names:SCD_n02850Imported
OrganismiSulfuricella denitrificans skB26Imported
Taxonomic identifieri1163617 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaHydrogenophilalesHydrogenophilaceaeSulfuricella
ProteomesiUP000015559: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei191 – 1911N6-carboxylysineUniRule annotation

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the RuBisCO large chain family. Type II subfamily.UniRule annotation

Phylogenomic databases

KOiK01601.

Family and domain databases

Gene3Di3.20.20.110. 1 hit.
3.30.70.150. 1 hit.
HAMAPiMF_01339. RuBisCO_L_type2.
InterProiIPR020871. RuBisCO.
IPR020878. RuBisCo_large_chain_AS.
IPR000685. RuBisCO_lsu_C.
IPR017443. RuBisCO_lsu_fd_N.
IPR017444. RuBisCO_lsu_N.
[Graphical view]
PfamiPF00016. RuBisCO_large. 1 hit.
PF02788. RuBisCO_large_N. 1 hit.
[Graphical view]
SUPFAMiSSF51649. SSF51649. 1 hit.
SSF54966. SSF54966. 1 hit.
PROSITEiPS00157. RUBISCO_LARGE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

S6AP25-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MDQSNRYADL SLKEEDLIKG DNHILVAYHM QPATGYGYLE VAAHIAAESS
60 70 80 90 100
TGTNVEVSTT DDFTKGVDAL VYFIDEAKGI MKVAYPNDLF DRNVTDGRAM
110 120 130 140 150
LVSFLTLAIG NNQGMGDVKH LQMQDFYVPW SMLRLYDGPA KDITDLWDIL
160 170 180 190 200
GRPRINGGYI AGTIIKPKLG LRPEPFAKAA YQFWLGGDFI KNDEPQGNQV
210 220 230 240 250
FCPTKKVIPL VYDSMKRAMD ETGQAKLFSA NITADDHYEM LARADYILET
260 270 280 290 300
FGPDANKVAF LVDGYVGGPG MITTARRQYP GQYLHYHRAG HGAITSPSAV
310 320 330 340 350
RGYTAFVLSK MSRLQGASGI HVGTMGYGKM EGGKDDRNIA YMIERDSADG
360 370 380 390 400
PYYHQEWHGM KPTTPIISGG MNALRLPGFF ENLGHGNVIN TSGGGSYGHI
410 420 430 440 450
DSPAAGAISL RQSYECWKAG ADPIEFAKEH KEFARAFESF PGDADKIFPG

WREKLGVHK
Length:459
Mass (Da):50,557
Last modified:October 16, 2013 - v1
Checksum:i4A820FEB687B8F86
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP013066 Genomic DNA. Translation: BAN36649.1.
RefSeqiYP_008547681.1. NC_022357.1.

Genome annotation databases

EnsemblBacteriaiBAN36649; BAN36649; SCD_n02850.
GeneIDi16926628.
KEGGisdr:SCD_n02850.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP013066 Genomic DNA. Translation: BAN36649.1 .
RefSeqi YP_008547681.1. NC_022357.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAN36649 ; BAN36649 ; SCD_n02850 .
GeneIDi 16926628.
KEGGi sdr:SCD_n02850.

Phylogenomic databases

KOi K01601.

Family and domain databases

Gene3Di 3.20.20.110. 1 hit.
3.30.70.150. 1 hit.
HAMAPi MF_01339. RuBisCO_L_type2.
InterProi IPR020871. RuBisCO.
IPR020878. RuBisCo_large_chain_AS.
IPR000685. RuBisCO_lsu_C.
IPR017443. RuBisCO_lsu_fd_N.
IPR017444. RuBisCO_lsu_N.
[Graphical view ]
Pfami PF00016. RuBisCO_large. 1 hit.
PF02788. RuBisCO_large_N. 1 hit.
[Graphical view ]
SUPFAMi SSF51649. SSF51649. 1 hit.
SSF54966. SSF54966. 1 hit.
PROSITEi PS00157. RUBISCO_LARGE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Draft genome sequence of a psychrotolerant sulfur-oxidizing bacterium, Sulfuricella denitrificans skB26, and proteomic insights into cold adaptation."
    Watanabe T., Kojima H., Fukui M.
    Appl. Environ. Microbiol. 78:6545-6549(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SkB26Imported.

Entry informationi

Entry nameiS6AP25_9PROT
AccessioniPrimary (citable) accession number: S6AP25
Entry historyi
Integrated into UniProtKB/TrEMBL: October 16, 2013
Last sequence update: October 16, 2013
Last modified: October 29, 2014
This is version 10 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Miscellaneous

The basic functional RuBisCO is composed of a large chain homodimer in a "head-to-tail" conformation. In contrast to form I RuBisCO, the form II RuBisCO are composed solely of large subunits.UniRule annotation

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3