Androgen receptor

Functionⁱ

Regions

Feature key	Position(s)	DescriptionActions	Graphical view	Length
DNA bindingⁱ	527 – 602	Nuclear receptorPROSITE-ProRule annotationAdd BLAST		76

GO - Molecular functionⁱ

androgen receptor activity Source: InterPro
sequence-specific DNA binding Source: InterPro
steroid binding Source: InterPro
zinc ion binding Source: InterPro

Complete GO annotation...

GO - Biological processⁱ

transcription, DNA-templated Source: UniProtKB-UniRule

Complete GO annotation...

Keywordsⁱ

Molecular function	DNA-bindingPROSITE-ProRule annotationSAAS annotation, ReceptorImported
Biological process	Transcription, Transcription regulationPROSITE-ProRule annotationSAAS annotation
Ligand	Metal-binding, Zinc

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: Androgen receptorImported
Organismⁱ	Ovis aries (Sheep)Imported
Taxonomic identifierⁱ	9940 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Laurasiatheria › Cetartiodactyla › Ruminantia › Pecora › Bovidae › Caprinae › Ovis

Subcellular locationⁱ

Nucleus
PROSITE-ProRule annotation
Automatic assertion according to rulesⁱ
- PROSITE-ProRule:PRU00407
SAAS annotation
Automatic assertion according to rulesⁱ
- SAAS:SAAS00817906

GO - Cellular componentⁱ

nucleus Source: UniProtKB-SubCell

Complete GO annotation...

Keywords - Cellular componentⁱ

NucleusPROSITE-ProRule annotationSAAS annotation

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	527 – 602	Nuclear receptor DNA-bindingInterPro annotationAdd BLAST		76

Sequence similaritiesⁱ

Belongs to the nuclear hormone receptor family.SAAS annotation

Keywords - Domainⁱ

Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

KEGG Orthology (KO) More...KOⁱ	K08557.

KOⁱ

K08557.

Family and domain databases

InterProⁱ	View protein in InterPro IPR001103. Andrgn_rcpt. IPR000536. Nucl_hrmn_rcpt_lig-bd. IPR001628. Znf_hrmn_rcpt.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF02166. Androgen_recep. 1 hit. PF00104. Hormone_recep. 1 hit. PF00105. zf-C4. 1 hit.
PRINTSⁱ	PR00521. ANDROGENR. PR00047. STROIDFINGER.
SMARTⁱ	View protein in SMART SM00430. HOLI. 1 hit. SM00399. ZnF_C4. 1 hit.
SUPFAMⁱ	SSF48508. SSF48508. 1 hit.
PROSITEⁱ	View protein in PROSITE PS00031. NUCLEAR_REC_DBD_1. 1 hit. PS51030. NUCLEAR_REC_DBD_2. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Complete.

S5U7M4-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MEVQLGLGRV YPRPPSKTYR GAFQNLFQSV CEVIQNPLPR HPEASSAAPP 
        60         70         80         90        100
GARLQQQQET SPRRQQQQQQ QREDGSPQVQ SRGPTGYLAL EEEQQPSQHH 
       110        120        130        140        150
SAPEGHPESG CVPEPRAASA GGKGLQQPPP APLDEDDSAA PSTLSLLGPT 
       160        170        180        190        200
FPGLSSCSTD LKDILSEAGT MQLLQQQQQQ QQEAVSEGSS GRAREATGAP 
       210        220        230        240        250
VSSKDSYLGG SSTISDSAKE LCKAVSVSMG LGVEALEHLS PGEQLRGDCM 
       260        270        280        290        300
YAPLLGPPAA VRPTPCAPLA ECKGSLLDDG PSKGTEETAE YSPFKAGYTK 
       310        320        330        340        350
GLDTDSLGCS GSGEAGGSGT LELPSTLSLY KSGALDEVAA YQTRDYYNFP 
       360        370        380        390        400
LALAGPPPPP PPPHPHARIK LENPLDYGSA WVAAAAQCRY GDLASLHGGG 
       410        420        430        440        450
AAGPGSGSPS AAASSSWHTL FTAEEGQLYG PAVCGGGGGG SAGEAGAAAP 
       460        470        480        490        500
YGYTRPPQGL ASQEGDFSPP DVWYPGGVVS RVPYPSPSCV KSEMGPWMEN 
       510        520        530        540        550
YSGPYGDMRL ETTRDHVLPI DYYFPPQKTC LICGDEASGC HYGALTCGSC 
       560        570        580        590        600
KVFFKRAAEG KQKYLCASRN DCTIDKFRRK NCPSCRLRKC YEAGMTLGAR 
       610        620        630        640        650
KLKKLGNLKL QEEGEASSAT SPTEEPAQKL TVSHIEGYEC QPIFLNVLEA 
       660        670        680        690        700
IEPGVVCAGH DNNQPDSFAA LLSSLNELGE RQLVHVVKWA KALPGFRNLH 
       710        720        730        740        750
VDDQMAVIQY SWMGLMVFAM GWRSFTNVNS RMLYFAPDLV FNEYRMHKSR 
       760        770        780        790        800
MYSQCVRMRH LSQEFGWLQI TPQEFLCMKA LLLFSIIPVD GLKNQKFFDE 
       810        820        830        840        850
LRMNYIKELD RIIACKRKNP TSCSRRFYQL TKLLDSVQPI ARELHQFTFD 
       860        870        880        890
LLIKSHMVSV DFPEMMAEII SVQVPKILSG KVKPIYFHTQ

Length:890

Mass (Da):96,466

Last modified:October 16, 2013 - v1

Checksum:ⁱE09D013ACEA5A427

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	KF227907 mRNA. Translation: AGS47181.1.
NCBI Reference Sequences More...RefSeqⁱ	NP_001295513.1. NM_001308584.1.
UniGeneⁱ	Oar.649.

Genome annotation databases

GeneIDⁱ	443042.
KEGGⁱ	oas:443042.

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	KF227907 mRNA. Translation: AGS47181.1.
NCBI Reference Sequences More...RefSeqⁱ	NP_001295513.1. NM_001308584.1.
UniGeneⁱ	Oar.649.

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

GeneIDⁱ	443042.
KEGGⁱ	oas:443042.

Organism-specific databases

CTDⁱ	367.

CTDⁱ

367.

Phylogenomic databases

KEGG Orthology (KO) More...KOⁱ	K08557.

KOⁱ

K08557.

Family and domain databases

InterProⁱ	View protein in InterPro IPR001103. Andrgn_rcpt. IPR000536. Nucl_hrmn_rcpt_lig-bd. IPR001628. Znf_hrmn_rcpt.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF02166. Androgen_recep. 1 hit. PF00104. Hormone_recep. 1 hit. PF00105. zf-C4. 1 hit.
PRINTSⁱ	PR00521. ANDROGENR. PR00047. STROIDFINGER.
SMARTⁱ	View protein in SMART SM00430. HOLI. 1 hit. SM00399. ZnF_C4. 1 hit.
SUPFAMⁱ	SSF48508. SSF48508. 1 hit.
PROSITEⁱ	View protein in PROSITE PS00031. NUCLEAR_REC_DBD_1. 1 hit. PS51030. NUCLEAR_REC_DBD_2. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	S5U7M4_SHEEP
Accessionⁱ	S5U7M4Primary (citable) accession number: S5U7M4
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	October 16, 2013
	Last sequence update:	October 16, 2013
	Last modified:	June 7, 2017
	This is version 24 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

UniProtKB - S5U7M4 (S5U7M4_SHEEP)

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Functionⁱ

Regions

GO - Molecular functionⁱ

GO - Biological processⁱ

Keywordsⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

Keywords - Cellular componentⁱ

Family & Domainsⁱ

Domains and Repeats

Sequence similaritiesⁱ

Keywords - Domainⁱ

Phylogenomic databases

Family and domain databases

Sequenceⁱ

Sequence databases

Genome annotation databases

Similar proteinsⁱ

Cross-referencesⁱ

Sequence databases

3D structure databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Family and domain databases

Entry informationⁱ

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - S5U7M4 (S5U7M4_SHEEP)

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Androgen receptor

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ