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Protein
Submitted name:

Cytochrome P450 family 2 subfamily C polypeptide 9

Gene

CYP2C9

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionMonooxygenaseUniRule annotation, Oxidoreductase
LigandHemeUniRule annotation, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Cytochrome P450 family 2 subfamily C polypeptide 9Imported
Gene namesi
Name:CYP2C9Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000138109.9

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 25Sequence analysisAdd BLAST25
ChainiPRO_501431351326 – 490Sequence analysisAdd BLAST465

Expressioni

Gene expression databases

BgeeiENSG00000138109
ExpressionAtlasiS5RV20 baseline and differential

Structurei

3D structure databases

SMRiS5RV20
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome P450 family.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG0156 Eukaryota
COG2124 LUCA
KOiK17719
OMAiICNNFSP
OrthoDBiEOG091G0BT8

Family and domain databases

Gene3Di1.10.630.10, 1 hit
InterProiView protein in InterPro
IPR001128 Cyt_P450
IPR017972 Cyt_P450_CS
IPR002401 Cyt_P450_E_grp-I
IPR036396 Cyt_P450_sf
PfamiView protein in Pfam
PF00067 p450, 1 hit
PRINTSiPR00463 EP450I
PR00385 P450
SUPFAMiSSF48264 SSF48264, 1 hit
PROSITEiView protein in PROSITE
PS00086 CYTOCHROME_P450, 1 hit

Sequencei

Sequence statusi: Complete.

S5RV20-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDSLVVLVLC LSCLLLLSLW RQSSGRGKLP PGPTPLPVIG NILQIGIKDI
60 70 80 90 100
SKSLTNLSKV YGPVFTLYFG LKPIVVLHGY EAVKEALIDL GEEFSGRGIF
110 120 130 140 150
PLAERANRGF GIVFSNGKKW KEIRRFSLMT LRNFGMGKRS IEDRVQEEAR
160 170 180 190 200
CLVEELRKTK ASPCDPTFIL GCAPCNVICS IIFHKRFDYK DQQFLNLMEK
210 220 230 240 250
LNENIKILSS PWIQICNNFS PIIDYFPGTH NKLLKNVAFM KSYILEKVKE
260 270 280 290 300
HQESMDMNNP QDFIDCFLMK MEKEKHNQPS EFTIESLENT AVDLFGAGTE
310 320 330 340 350
TTSTTLRYAL LLLLKHPEVT AKVQEEIERV IGRNRSPCMQ DRSHMPYTDA
360 370 380 390 400
VVHEVQRYID LLPTSLPHAV TCDIKFRNYL IPKGTTILIS LTSVLHDNKE
410 420 430 440 450
FPNPEMFDPH HFLDEGGNFK KSKYFMPFSA GKRICVGEAL AGMELFLFLT
460 470 480 490
SILQNFNLKS LVDPKNLDTT PVVNGFASVP PFYQLCFIPV
Length:490
Mass (Da):55,628
Last modified:October 16, 2013 - v1
Checksum:i4FDFC395303A4E3E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KF248014 Genomic DNA Translation: AGS09721.1
KF248015 Genomic DNA Translation: AGS09722.1
KF248016 Genomic DNA Translation: AGS09723.1
KF248018 Genomic DNA Translation: AGS09725.1
KF248020 Genomic DNA Translation: AGS09727.1
KF248021 Genomic DNA Translation: AGS09728.1
KF248023 Genomic DNA Translation: AGS09730.1
KF248025 Genomic DNA Translation: AGS09732.1
KF248029 Genomic DNA Translation: AGS09736.1
KF248033 Genomic DNA Translation: AGS09740.1
KF248036 Genomic DNA Translation: AGS09743.1
KF248038 Genomic DNA Translation: AGS09745.1
KF248039 Genomic DNA Translation: AGS09746.1
KF248041 Genomic DNA Translation: AGS09748.1
KF248042 Genomic DNA Translation: AGS09749.1
KF248043 Genomic DNA Translation: AGS09750.1
KF248044 Genomic DNA Translation: AGS09751.1
KF248050 Genomic DNA Translation: AGS09757.1
KF248051 Genomic DNA Translation: AGS09758.1
KF248052 Genomic DNA Translation: AGS09759.1
KF248053 Genomic DNA Translation: AGS09760.1
KF248054 Genomic DNA Translation: AGS09761.1
KF248055 Genomic DNA Translation: AGS09762.1
KF248056 Genomic DNA Translation: AGS09763.1
KF248057 Genomic DNA Translation: AGS09764.1
RefSeqiNP_000762.2, NM_000771.3
XP_016871247.1, XM_017015758.1
UniGeneiHs.282624

Genome annotation databases

GeneIDi1559
KEGGihsa:1559
UCSCiuc001kka.5 human

Similar proteinsi

Entry informationi

Entry nameiS5RV20_HUMAN
AccessioniPrimary (citable) accession number: S5RV20
Entry historyiIntegrated into UniProtKB/TrEMBL: October 16, 2013
Last sequence update: October 16, 2013
Last modified: May 23, 2018
This is version 42 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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