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Protein
Submitted name:

Cytochrome P450 family 2 subfamily C polypeptide 9

Gene

CYP2C9

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionMonooxygenaseUniRule annotation, Oxidoreductase
LigandHemeUniRule annotation, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Cytochrome P450 family 2 subfamily C polypeptide 9Imported
Gene namesi
Name:CYP2C9Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000138109.9.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 25Sequence analysisAdd BLAST25
ChainiPRO_501015041626 – 490Sequence analysisAdd BLAST465

Expressioni

Gene expression databases

BgeeiENSG00000138109.
ExpressionAtlasiS5RV20. baseline and differential.

Structurei

3D structure databases

SMRiS5RV20.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome P450 family.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG0156. Eukaryota.
COG2124. LUCA.
KOiK17719.
OMAiICNNFSP.
OrthoDBiEOG091G0BT8.

Family and domain databases

InterProiView protein in InterPro
IPR001128. Cyt_P450.
IPR017972. Cyt_P450_CS.
IPR002401. Cyt_P450_E_grp-I.
PfamiView protein in Pfam
PF00067. p450. 1 hit.
PRINTSiPR00463. EP450I.
PR00385. P450.
SUPFAMiSSF48264. SSF48264. 1 hit.
PROSITEiView protein in PROSITE
PS00086. CYTOCHROME_P450. 1 hit.

Sequencei

Sequence statusi: Complete.

S5RV20-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDSLVVLVLC LSCLLLLSLW RQSSGRGKLP PGPTPLPVIG NILQIGIKDI
60 70 80 90 100
SKSLTNLSKV YGPVFTLYFG LKPIVVLHGY EAVKEALIDL GEEFSGRGIF
110 120 130 140 150
PLAERANRGF GIVFSNGKKW KEIRRFSLMT LRNFGMGKRS IEDRVQEEAR
160 170 180 190 200
CLVEELRKTK ASPCDPTFIL GCAPCNVICS IIFHKRFDYK DQQFLNLMEK
210 220 230 240 250
LNENIKILSS PWIQICNNFS PIIDYFPGTH NKLLKNVAFM KSYILEKVKE
260 270 280 290 300
HQESMDMNNP QDFIDCFLMK MEKEKHNQPS EFTIESLENT AVDLFGAGTE
310 320 330 340 350
TTSTTLRYAL LLLLKHPEVT AKVQEEIERV IGRNRSPCMQ DRSHMPYTDA
360 370 380 390 400
VVHEVQRYID LLPTSLPHAV TCDIKFRNYL IPKGTTILIS LTSVLHDNKE
410 420 430 440 450
FPNPEMFDPH HFLDEGGNFK KSKYFMPFSA GKRICVGEAL AGMELFLFLT
460 470 480 490
SILQNFNLKS LVDPKNLDTT PVVNGFASVP PFYQLCFIPV
Length:490
Mass (Da):55,628
Last modified:October 16, 2013 - v1
Checksum:i4FDFC395303A4E3E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KF248014 Genomic DNA. Translation: AGS09721.1.
KF248015 Genomic DNA. Translation: AGS09722.1.
KF248016 Genomic DNA. Translation: AGS09723.1.
KF248018 Genomic DNA. Translation: AGS09725.1.
KF248020 Genomic DNA. Translation: AGS09727.1.
KF248021 Genomic DNA. Translation: AGS09728.1.
KF248023 Genomic DNA. Translation: AGS09730.1.
KF248025 Genomic DNA. Translation: AGS09732.1.
KF248029 Genomic DNA. Translation: AGS09736.1.
KF248033 Genomic DNA. Translation: AGS09740.1.
KF248036 Genomic DNA. Translation: AGS09743.1.
KF248038 Genomic DNA. Translation: AGS09745.1.
KF248039 Genomic DNA. Translation: AGS09746.1.
KF248041 Genomic DNA. Translation: AGS09748.1.
KF248042 Genomic DNA. Translation: AGS09749.1.
KF248043 Genomic DNA. Translation: AGS09750.1.
KF248044 Genomic DNA. Translation: AGS09751.1.
KF248050 Genomic DNA. Translation: AGS09757.1.
KF248051 Genomic DNA. Translation: AGS09758.1.
KF248052 Genomic DNA. Translation: AGS09759.1.
KF248053 Genomic DNA. Translation: AGS09760.1.
KF248054 Genomic DNA. Translation: AGS09761.1.
KF248055 Genomic DNA. Translation: AGS09762.1.
KF248056 Genomic DNA. Translation: AGS09763.1.
KF248057 Genomic DNA. Translation: AGS09764.1.
RefSeqiNP_000762.2. NM_000771.3.
XP_016871247.1. XM_017015758.1.
UniGeneiHs.282624.

Genome annotation databases

GeneIDi1559.
KEGGihsa:1559.
UCSCiuc001kka.5. human.

Similar proteinsi

Entry informationi

Entry nameiS5RV20_HUMAN
AccessioniPrimary (citable) accession number: S5RV20
Entry historyiIntegrated into UniProtKB/TrEMBL: October 16, 2013
Last sequence update: October 16, 2013
Last modified: September 27, 2017
This is version 35 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.