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Protein

Ubiquinol-cytochrome c reductase iron-sulfur subunit

Gene

I633_03930

Organism
Alteromonas macleodii str. 'English Channel 615'
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.UniRule annotation

Catalytic activityi

Quinol + 2 ferricytochrome c = quinone + 2 ferrocytochrome c + 2 H+.UniRule annotation

Cofactori

Protein has several cofactor binding sites:
  • Note: Binds 1 2Fe-2S cluster per subunit.
  • [2Fe-2S] clusterUniRule annotationNote: Binds 1 [2Fe-2S] cluster per subunit.UniRule annotation

GO - Molecular functioni

  1. 2 iron, 2 sulfur cluster binding Source: UniProtKB-KW
  2. metal ion binding Source: UniProtKB-KW
  3. ubiquinol-cytochrome-c reductase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotation

Keywords - Biological processi

Electron transportUniRule annotation, Transport

Keywords - Ligandi

2Fe-2SUniRule annotation, Iron, Iron-sulfur, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Ubiquinol-cytochrome c reductase iron-sulfur subunitUniRule annotation (EC:1.10.2.2UniRule annotation)
Gene namesi
ORF Names:I633_03930Imported
OrganismiAlteromonas macleodii str. 'English Channel 615'Imported
Taxonomic identifieri1300253 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesAlteromonadaceaeAlteromonas
ProteomesiUP000014909 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. membrane Source: InterPro
Complete GO annotation...

Interactioni

Subunit structurei

The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Contains 1 Rieske domain.UniRule annotation

Phylogenomic databases

KOiK00411.

Family and domain databases

Gene3Di2.102.10.10. 1 hit.
InterProiIPR017941. Rieske_2Fe-2S.
IPR014349. Rieske_Fe-S_prot.
IPR005805. Rieske_Fe-S_prot_C.
IPR006311. TAT_signal.
IPR019470. Ubiq_cytC_Rdtase_Fe-S_su_TAT.
IPR006317. Ubiquinol_cyt_c_Rdtase_Fe-S-su.
[Graphical view]
PANTHERiPTHR10134. PTHR10134. 1 hit.
PfamiPF00355. Rieske. 1 hit.
PF10399. UCR_Fe-S_N. 1 hit.
[Graphical view]
PRINTSiPR00162. RIESKE.
SUPFAMiSSF50022. SSF50022. 1 hit.
TIGRFAMsiTIGR01416. Rieske_proteo. 1 hit.
PROSITEiPS51296. RIESKE. 1 hit.
PS51318. TAT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

S5ABE4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSNVSVDATE SAHNENQPEN NTRRRFLTVA TSVVGGVGVV GAAVPFIASW
60 70 80 90 100
NPSAKAKAAG ADVEVDISGI EPGQLVRVMW RSKPVWIVRR TPEILEELGT
110 120 130 140 150
HEDKLKDPNS EAEQQPTFAQ NRFRSMKEEY LILVGICTHL GCSPQHLKDG
160 170 180 190 200
AFEEVVEGVP DGFFCPCHGS KFDMAGRVFQ NVPAPLNLVV PPYQFVDDNT
210
VIIGSEAEVA
Length:210
Mass (Da):22,872
Last modified:October 15, 2013 - v1
Checksum:i4DDBCF3AEB1BB61B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP004846 Genomic DNA. Translation: AGP77055.1.
RefSeqiYP_008191705.1. NC_021716.1.

Genome annotation databases

EnsemblBacteriaiAGP77055; AGP77055; I633_03930.
GeneIDi16096376.
KEGGiamh:I633_03930.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP004846 Genomic DNA. Translation: AGP77055.1.
RefSeqiYP_008191705.1. NC_021716.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAGP77055; AGP77055; I633_03930.
GeneIDi16096376.
KEGGiamh:I633_03930.

Phylogenomic databases

KOiK00411.

Family and domain databases

Gene3Di2.102.10.10. 1 hit.
InterProiIPR017941. Rieske_2Fe-2S.
IPR014349. Rieske_Fe-S_prot.
IPR005805. Rieske_Fe-S_prot_C.
IPR006311. TAT_signal.
IPR019470. Ubiq_cytC_Rdtase_Fe-S_su_TAT.
IPR006317. Ubiquinol_cyt_c_Rdtase_Fe-S-su.
[Graphical view]
PANTHERiPTHR10134. PTHR10134. 1 hit.
PfamiPF00355. Rieske. 1 hit.
PF10399. UCR_Fe-S_N. 1 hit.
[Graphical view]
PRINTSiPR00162. RIESKE.
SUPFAMiSSF50022. SSF50022. 1 hit.
TIGRFAMsiTIGR01416. Rieske_proteo. 1 hit.
PROSITEiPS51296. RIESKE. 1 hit.
PS51318. TAT. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genomic Diversity of "Deep Ecotype" Alteromonas macleodii Isolates: Evidence for Pan-Mediterranean Clonal Frames."
    Lopez-Perez M., Gonzaga A., Rodriguez-Valera F.
    Genome Biol. Evol. 5:1220-1232(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: English Channel 615Imported.

Entry informationi

Entry nameiS5ABE4_ALTMA
AccessioniPrimary (citable) accession number: S5ABE4
Entry historyi
Integrated into UniProtKB/TrEMBL: October 15, 2013
Last sequence update: October 15, 2013
Last modified: January 6, 2015
This is version 12 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Miscellaneous

The Rieske protein is a high potential 2Fe-2S protein.UniRule annotation

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.