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Protein
Submitted name:

MHC class I antigen

Gene

HLA-C

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Names & Taxonomyi

Protein namesi
Submitted name:
MHC class I antigenImported
Gene namesi
Name:HLA-CImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Proteomic databases

PaxDbiS4T6Q4.
PeptideAtlasiS4T6Q4.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000365402.

Structurei

3D structure databases

ProteinModelPortaliS4T6Q4.
SMRiS4T6Q4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 178MHC_I-like_Ag-recogInterPro annotationAdd BLAST178

Sequence similaritiesi

Belongs to the MHC class I family.UniRule annotation

Phylogenomic databases

eggNOGiENOG410II5V. Eukaryota.
ENOG4111K8F. LUCA.

Family and domain databases

Gene3Di3.30.500.10. 1 hit.
InterProiIPR011161. MHC_I-like_Ag-recog.
IPR011162. MHC_I/II-like_Ag-recog.
IPR001039. MHC_I_a_a1/a2.
[Graphical view]
PfamiPF00129. MHC_I. 1 hit.
[Graphical view]
PRINTSiPR01638. MHCCLASSI.
SUPFAMiSSF54452. SSF54452. 1 hit.

Sequencei

Sequence statusi: Fragment.

S4T6Q4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
SHSMRYFDTA VSRPGRGEPR FISVGYVDDT QFVRFDSDAA SPRGEPRAPW
60 70 80 90 100
VEQEGPEYWD RETQKYKRQA QADRVSLRNL RGYYNQSEDG SHTLQRMSGC
110 120 130 140 150
DLGPDGRLLR GYDQSAYDGK DYIALNEDLR SWTAADTAAQ ITQRKLEAAR
160 170 180
AAEQLRAYLE GTCVEWLRRY LENGRETLQR A
Length:181
Mass (Da):20,853
Last modified:October 16, 2013 - v1
Checksum:i302FA12458F5D66D
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei181Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JX458895 Genomic DNA. Translation: AFU93105.1.
UniGeneiHs.656020.
Hs.743218.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JX458895 Genomic DNA. Translation: AFU93105.1.
UniGeneiHs.656020.
Hs.743218.

3D structure databases

ProteinModelPortaliS4T6Q4.
SMRiS4T6Q4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000365402.

Proteomic databases

PaxDbiS4T6Q4.
PeptideAtlasiS4T6Q4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiENOG410II5V. Eukaryota.
ENOG4111K8F. LUCA.

Miscellaneous databases

ChiTaRSiHLA-C. human.

Family and domain databases

Gene3Di3.30.500.10. 1 hit.
InterProiIPR011161. MHC_I-like_Ag-recog.
IPR011162. MHC_I/II-like_Ag-recog.
IPR001039. MHC_I_a_a1/a2.
[Graphical view]
PfamiPF00129. MHC_I. 1 hit.
[Graphical view]
PRINTSiPR01638. MHCCLASSI.
SUPFAMiSSF54452. SSF54452. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiS4T6Q4_HUMAN
AccessioniPrimary (citable) accession number: S4T6Q4
Entry historyi
Integrated into UniProtKB/TrEMBL: October 16, 2013
Last sequence update: October 16, 2013
Last modified: November 2, 2016
This is version 13 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.