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Protein
Submitted name:

DNA-binding protein Ikaros

Gene

IKZF1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
DNA-binding protein IkarosImported
Submitted name:
IKAROS family zinc finger 1 isoform 14Imported
Gene namesi
Name:IKZF1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 7

Organism-specific databases

EuPathDBiHostDB:ENSG00000185811.16.
HGNCiHGNC:13176. IKZF1.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000185811.

Expressioni

Gene expression databases

BgeeiENSG00000185811.
ExpressionAtlasiR9R4D9. baseline and differential.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini78 – 100C2H2-typeInterPro annotationAdd BLAST23

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
GeneTreeiENSGT00550000074392.
KOiK09220.

Family and domain databases

Gene3Di4.10.1050.10. 1 hit.
InterProiView protein in InterPro
IPR026939. At2g23090-like.
IPR036236. Znf_C2H2_sf.
IPR013087. Znf_C2H2_type.
SMARTiView protein in SMART
SM00355. ZnF_C2H2. 3 hits.
SUPFAMiSSF57667. SSF57667. 2 hits.
PROSITEiView protein in PROSITE
PS00028. ZINC_FINGER_C2H2_1. 2 hits.
PS50157. ZINC_FINGER_C2H2_2. 1 hit.

Sequencei

Sequence statusi: Complete.

R9R4D9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDADEGQDMS QVSGKESPPV SDTPDEGDEP MPIPEDLSTT SGGQQSSKSD
60 70 80 90 100
RVVVTYGADD FRDFHAIIPK SFSRERPFQC NQCGASFTQK GNLLRHIKLH
110 120 130 140 150
KPLAEGTPRS NHSAQDSAVE NLLLLSKAKL VPSEREASPS NSCQDSTDTE
160 170 180 190 200
SNNEEQRSGL IYLTNHIAPH ARNGLSLKEE HRAYDLLRAA SENSQDALRV
210 220 230 240 250
VSTSGEQMKV YKCEHCRVLF LDHVMYTIHM GCHGFRDPFE CNMCGYHSQD
260
RYEFSSHITR GEHRFHMS
Length:268
Mass (Da):30,031
Last modified:September 18, 2013 - v1
Checksum:i3A4F6647250035C0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC124014 Genomic DNA. No translation available.
AC233268 Genomic DNA. No translation available.
AUXG01000057 Genomic DNA. No translation available.
JX459579 mRNA. Translation: AGI59420.1.
RefSeqiNP_001207694.1. NM_001220765.2.
NP_001207696.1. NM_001220767.2.
NP_001207697.1. NM_001220768.2.
NP_001207699.1. NM_001220770.2.
NP_001207700.1. NM_001220771.2.
NP_001278766.1. NM_001291837.1.
NP_001278767.1. NM_001291838.1.
NP_001278768.1. NM_001291839.1.
NP_001278769.1. NM_001291840.1.
NP_001278770.1. NM_001291841.1.
NP_001278771.1. NM_001291842.1.
NP_001278772.1. NM_001291843.1.
NP_001278773.1. NM_001291844.1.
NP_006051.1. NM_006060.5.
UniGeneiHs.435949.
Hs.488251.
Hs.646004.
Hs.731495.

Genome annotation databases

EnsembliENST00000612658; ENSP00000483016; ENSG00000185811.
GeneIDi10320.
KEGGihsa:10320.
UCSCiuc064dpn.1. human.

Similar proteinsi

Entry informationi

Entry nameiR9R4D9_HUMAN
AccessioniPrimary (citable) accession number: R9R4D9
Entry historyiIntegrated into UniProtKB/TrEMBL: September 18, 2013
Last sequence update: September 18, 2013
Last modified: November 22, 2017
This is version 38 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported