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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Mycobacterium abscessus subsp. bolletii 50594
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetaseUniRule annotation, Ligase
Biological processProtein biosynthesisUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
ORF Names:MASS_1425Imported
OrganismiMycobacterium abscessus subsp. bolletii 50594Imported
Taxonomic identifieri1303024 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium abscessus
Proteomesi
  • UP000013961 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Monomer.UniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 96Arg_tRNA_synt_NInterPro annotationAdd BLAST90
Domaini432 – 553DALR_1InterPro annotationAdd BLAST122

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi133 – 143"HIGH" regionUniRule annotationAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

KOiK01887.

Family and domain databases

CDDicd00671. ArgRS_core. 1 hit.
Gene3Di3.30.1360.70. 1 hit.
3.40.50.620. 2 hits.
HAMAPiMF_00123. Arg_tRNA_synth. 1 hit.
InterProiView protein in InterPro
IPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR036695. Arg-tRNA-synth_N_sf.
IPR035684. ArgRS_core.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_Ia_anticodon-bd.
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiView protein in Pfam
PF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
PRINTSiPR01038. TRNASYNTHARG.
SMARTiView protein in SMART
SM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.
PROSITEiView protein in PROSITE
PS00178. AA_TRNA_LIGASE_I. 1 hit.

Sequencei

Sequence statusi: Complete.

R4U8Q2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIAVTPADLA DLLRSTATTV LDERGLDTSA LPAVVTVERP RNPEHGDYAT
60 70 80 90 100
NVALQVAKKV GVAPRDLAGW LVEALVSNAA IAGAEIAGPG FVNLRIAADA
110 120 130 140 150
QGTIVANILK AGETYGNSDA QGTHTINLEF VSANPTGPIH IGGTRWAAVG
160 170 180 190 200
DALGRLLARQ GAKVTREYYF NDHGAQIDRF VRSLIASAEG KEAPEDGYAG
210 220 230 240 250
DYIADIAKQV ITQRPEALSL TEPERSEVFR EIGVDLMFTH IKESLHEFGT
260 270 280 290 300
DFDVFTHEDS MHTSGRVQEA IAQLRKTGNI YEKDGASWLR SSNFGDDKDR
310 320 330 340 350
VVIKSDGNPA YIAGDIAYYL DKRERGFDLC IYMLGADHHG YIARLKAVAA
360 370 380 390 400
ALGYDADSVE VLIGQMVNLV RDGQPVRMSK RAGTVITLDD LVDAIGVDAA
410 420 430 440 450
RYALIRSSVD TSIDIDLELW ASASSENPVY YVQYAHARLC ALARNAADLG
460 470 480 490 500
LQHSTEHLEL LTHEKEGALI RGLGEFGRIL QNAAVLREPH RVARYLEDIA
510 520 530 540 550
GDYHRFYDSC RVLPQGDETP GDLHAARLAL CLATRQVIAN GLDILGVSAP

ERM
Length:553
Mass (Da):59,953
Last modified:July 24, 2013 - v1
Checksum:iA65D5E3129C0D80D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP004374 Genomic DNA. Translation: AGM28027.1.

Genome annotation databases

EnsemblBacteriaiAGM28027; AGM28027; MASS_1425.
KEGGimabb:MASS_1425.
PATRICifig|1303024.3.peg.1493.

Similar proteinsi

Entry informationi

Entry nameiR4U8Q2_9MYCO
AccessioniPrimary (citable) accession number: R4U8Q2
Entry historyiIntegrated into UniProtKB/TrEMBL: July 24, 2013
Last sequence update: July 24, 2013
Last modified: November 22, 2017
This is version 27 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported