ID   R4LMQ9_ACTS9            Unreviewed;       548 AA.
AC   R4LMQ9;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 48.
DE   RecName: Full=Alpha-amylase {ECO:0000256|RuleBase:RU361134};
DE            EC=3.2.1.1 {ECO:0000256|RuleBase:RU361134};
GN   Name=malL {ECO:0000313|EMBL:AGL20672.1};
GN   ORFNames=L083_7162 {ECO:0000313|EMBL:AGL20672.1};
OS   Actinoplanes sp. (strain N902-109).
OC   Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC   Micromonosporaceae; Actinoplanes.
OX   NCBI_TaxID=649831 {ECO:0000313|EMBL:AGL20672.1, ECO:0000313|Proteomes:UP000013541};
RN   [1] {ECO:0000313|EMBL:AGL20672.1, ECO:0000313|Proteomes:UP000013541}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=N902-109 {ECO:0000313|EMBL:AGL20672.1,
RC   ECO:0000313|Proteomes:UP000013541};
RA   Hu H., Huang H., Lu X., Zhu B.;
RT   "Comparative analysis of rapamycin biosynthesis clusters between
RT   Streptomyces hygroscopicus ATCC 29253 and Actinoplanes sp. N902-109.";
RL   Submitted (MAY-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Endohydrolysis of (1->4)-alpha-D-glucosidic linkages in
CC         polysaccharides containing three or more (1->4)-alpha-linked D-
CC         glucose units.; EC=3.2.1.1; Evidence={ECO:0000256|RuleBase:RU361134};
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 13 family.
CC       {ECO:0000256|ARBA:ARBA00008061, ECO:0000256|RuleBase:RU003615}.
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DR   EMBL; CP005929; AGL20672.1; -; Genomic_DNA.
DR   RefSeq; WP_015625229.1; NC_021191.1.
DR   AlphaFoldDB; R4LMQ9; -.
DR   STRING; 649831.L083_7162; -.
DR   KEGG; actn:L083_7162; -.
DR   PATRIC; fig|649831.3.peg.7096; -.
DR   eggNOG; COG0366; Bacteria.
DR   HOGENOM; CLU_006462_2_1_11; -.
DR   OrthoDB; 9802433at2; -.
DR   Proteomes; UP000013541; Chromosome.
DR   GO; GO:0004556; F:alpha-amylase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0043169; F:cation binding; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
DR   CDD; cd11334; AmyAc_TreS; 1.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   InterPro; IPR006046; Alpha_amylase.
DR   InterPro; IPR006047; Glyco_hydro_13_cat_dom.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   InterPro; IPR045857; O16G_dom_2.
DR   PANTHER; PTHR10357; ALPHA-AMYLASE FAMILY MEMBER; 1.
DR   PANTHER; PTHR10357:SF219; MALTOSE ALPHA-D-GLUCOSYLTRANSFERASE; 1.
DR   Pfam; PF00128; Alpha-amylase; 1.
DR   PRINTS; PR00110; ALPHAAMYLASE.
DR   SMART; SM00642; Aamy; 1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE   3: Inferred from homology;
KW   Carbohydrate metabolism {ECO:0000256|RuleBase:RU361134};
KW   Glycosidase {ECO:0000256|RuleBase:RU361134};
KW   Hydrolase {ECO:0000256|RuleBase:RU361134};
KW   Reference proteome {ECO:0000313|Proteomes:UP000013541}.
FT   DOMAIN          13..396
FT                   /note="Glycosyl hydrolase family 13 catalytic"
FT                   /evidence="ECO:0000259|SMART:SM00642"
SQ   SEQUENCE   548 AA;  62337 MW;  57C6050947E5F482 CRC64;
     MSDRWYEKAV IYCLDIDTYA DSNGDGVGDI RGLIGRLDYL ARLGITCLWL NPIHPSPDKD
     DGYDVADFYN VDPRFGTLGD FAELLHQAQN RGIKVIIDLV VNHTSDQHPW FQSARQSPES
     PYRDWYVWSE TEPPDRNQGM VFPGEQKETW TYDRTAKQWF YHRFYKFQPD LNITNPQVRE
     EIKKICAFWL QLGVAGFRMD AVPFIIEETE PGNPDAPKDF AFLTDLRQHI QWRRGDAVLL
     AEANVEADQL KHFFGDQGGS ANRIHMLFDF MLNGRLMLAL ARRHPEVIID ALQDTPKLPS
     GAQWATFLRN HDEVDLSRLT AEQRAEVFGQ FGPDESMQLY GRGIRRRLAP MLGGDRRRLE
     LAYALQFSLR GTPVLRYGEE IGMGDDLSLE GRDAIRTPMQ WSSLPNGGFS TATPDELIRP
     VVTGGDFGYE QVNVTLQRHD PQSLLSWFER MIRTLRETPE VGSGTCKHVD IPVPAGVLVH
     RADADTGCMV FIHNLGPDDG VVDLSSLEPE AEYPNDVLAD QEYPDLGKMD ALPIGGFGYR
     WIRLKRFA
//