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Protein

Cytochrome c oxidase subunit 2

Gene

cox2

Organism
Cyanidioschyzon merolae (Red alga)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1.UniRule annotation

Cofactori

Cu cationUniRule annotationNote: Binds a copper A center.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductaseImported
Biological processElectron transport, Respiratory chainUniRule annotationSAAS annotation, Transport
LigandCopperUniRule annotationSAAS annotation, Metal-bindingUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c oxidase subunit 2UniRule annotation
Gene namesi
Name:cox2Imported
Encoded oniMitochondrionImported
OrganismiCyanidioschyzon merolae (Red alga)Imported
Taxonomic identifieri45157 [NCBI]
Taxonomic lineageiEukaryotaRhodophytaBangiophyceaeCyanidialesCyanidiaceaeCyanidioschyzon

Subcellular locationi

  • Mitochondrion inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei49 – 69HelicalSequence analysisAdd BLAST21
Transmembranei90 – 112HelicalSequence analysisAdd BLAST23

GO - Cellular componenti

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membraneUniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ9ZZQ9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini23 – 118COX2_TMInterPro annotationAdd BLAST96
Domaini119 – 257COX2_CUAInterPro annotationAdd BLAST139

Sequence similaritiesi

Belongs to the cytochrome c oxidase subunit 2 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG4767 Eukaryota
COG1622 LUCA
OMAiWSYEYTD
PhylomeDBiQ9ZZQ9

Family and domain databases

CDDicd13912 CcO_II_C, 1 hit
Gene3Di1.10.287.90, 1 hit
2.60.40.420, 1 hit
InterProiView protein in InterPro
IPR002429 CcO_II-like_C
IPR034210 CcO_II_C
IPR008972 Cupredoxin
IPR014222 Cyt_c_oxidase_su2
IPR011759 Cyt_c_oxidase_su2_TM_dom
IPR036257 Cyt_c_oxidase_su2_TM_sf
PfamiView protein in Pfam
PF00116 COX2, 1 hit
PF02790 COX2_TM, 1 hit
SUPFAMiSSF49503 SSF49503, 1 hit
SSF81464 SSF81464, 1 hit
TIGRFAMsiTIGR02866 CoxB, 1 hit
PROSITEiView protein in PROSITE
PS50857 COX2_CUA, 1 hit
PS50999 COX2_TM, 1 hit

Sequencei

Sequence statusi: Complete.

Q9ZZQ9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKSVNTIVIF LITFGYEVIY NDAPVLWQTG FQDPATPVME GIINLHHDFI
60 70 80 90 100
FFFILIFVFV LWILLRAIYF FNSRVNKVAI NYSHGTLIEL IWTIIPIMIL
110 120 130 140 150
MTIAVPSFAL LYSIDEIINP AVTVKAVGHQ WYWSYEYSDY IGENGEIINF
160 170 180 190 200
DSYIIPEEDL EIGQFRLLEV DNRIIVPVNT HVRVIVTSAD VIHSWAVPSL
210 220 230 240 250
GVKCDGIPGR LNQISLFIKR EGVYYGQCSE LCGVNHGFIP IVVEAVPLDN
260
YIDWIQKKLY A
Length:261
Mass (Da):29,912
Last modified:May 1, 1999 - v1
Checksum:iD31DC51153FE71E2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D89861 Genomic DNA Translation: BAA34656.1
PIRiE58930
RefSeqiNP_059353.1, NC_000887.3

Genome annotation databases

EnsemblPlantsiCMW010CT; CMW010CT; CMW010C
GeneIDi3125647
GrameneiCMW010CT; CMW010CT; CMW010C

Similar proteinsi

Entry informationi

Entry nameiQ9ZZQ9_CYAME
AccessioniPrimary (citable) accession number: Q9ZZQ9
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 1999
Last sequence update: May 1, 1999
Last modified: March 28, 2018
This is version 108 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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