Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Cytochrome c oxidase subunit 1

Gene

cox1

Organism
Gracilariopsis lemaneiformis (Red alga) (Gracilaria lemaneiformis)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.UniRule annotation

Catalytic activityi

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.UniRule annotation

Pathwayi: oxidative phosphorylation

This protein is involved in the pathway oxidative phosphorylation, which is part of Energy metabolism.UniRule annotationSAAS annotation
View all proteins of this organism that are known to be involved in the pathway oxidative phosphorylation and in Energy metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotationImported
Biological processElectron transport, Respiratory chainUniRule annotation, Transport
LigandCopperUniRule annotationSAAS annotation, HemeUniRule annotation, Iron, Metal-binding

Enzyme and pathway databases

UniPathwayiUPA00705

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c oxidase subunit 1UniRule annotation (EC:1.9.3.1UniRule annotation)
Gene namesi
Name:cox1Imported
Encoded oniMitochondrionImported
OrganismiGracilariopsis lemaneiformis (Red alga) (Gracilaria lemaneiformis)Imported
Taxonomic identifieri2782 [NCBI]
Taxonomic lineageiEukaryotaRhodophytaFlorideophyceaeRhodymeniophycidaeGracilarialesGracilariaceaeGracilariopsis

Subcellular locationi

  • Mitochondrion inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membraneUniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ9ZY18
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini6 – 527COX1InterPro annotationAdd BLAST522

Sequence similaritiesi

Belongs to the heme-copper respiratory oxidase family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotation

Family and domain databases

CDDicd01663 Cyt_c_Oxidase_I, 1 hit
Gene3Di1.20.210.10, 1 hit
InterProiView protein in InterPro
IPR023616 Cyt_c_oxase-like_su1_dom
IPR036927 Cyt_c_oxase-like_su1_sf
IPR000883 Cyt_C_Oxase_1
IPR023615 Cyt_c_Oxase_su1_BS
IPR033944 Cyt_c_oxase_su1_dom
IPR014241 Cyt_c_oxidase_su1_bac
PANTHERiPTHR10422 PTHR10422, 1 hit
PfamiView protein in Pfam
PF00115 COX1, 1 hit
PRINTSiPR01165 CYCOXIDASEI
SUPFAMiSSF81442 SSF81442, 1 hit
TIGRFAMsiTIGR02891 CtaD_CoxA, 1 hit
PROSITEiView protein in PROSITE
PS50855 COX1, 1 hit
PS00077 COX1_CUB, 1 hit

Sequencei

Sequence statusi: Complete.

Q9ZY18-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQFSFNQWVS RWIFSTNHKD IGTLYLIFGA FSGVLGGCMS MLIRMELAQP
60 70 80 90 100
GNQFLLGNHQ IYNVLITAHA FLMIFFMVMP VMIGGFGNWL VPIMIGSPDM
110 120 130 140 150
AFPRLNNISF WLLPPSLCLL LASAIVEVGV GTGWTVYPPL SSIQSHSGGA
160 170 180 190 200
VDLAIFSLHI SGASSILGAI NFISTILNMR NPGQSMYRMP LFVWSIFITA
210 220 230 240 250
FLLLLAVPVL AGAITMLLTD RNFNTTFFDP AGGGDPVLYQ HLFWFFGHPE
260 270 280 290 300
VYILILPGFG MVSHIVSTFS RKPVFGYIGM VYAMVSIGVL GFIVWAHHMY
310 320 330 340 350
TVGLDVDTRA YFTAATMIIA VPTGIKIFSW IATMWEGSIH FKTPMLFATG
360 370 380 390 400
FIFLFTIGGL TGIVLANSGL DISLHDTYYV VAHFHYVLSM GAVFAIFAGF
410 420 430 440 450
YYWFGKITGV QYPELLGQIH FWSTFIGVNL TFMPMHFLGL AGMPRRIPDY
460 470 480 490 500
PDAYAGWNLV ASYGSYMALF STLFFFYLVF VSLTSKNPCV SAPWNFEQSI
510 520 530
TKGNSTLEWV VTSPPAYHTF EEMPLICETV K
Length:531
Mass (Da):59,067
Last modified:May 1, 1999 - v1
Checksum:i4C0E66950DE377B6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF118119 Genomic DNA Translation: AAD17226.1

Similar proteinsi

Entry informationi

Entry nameiQ9ZY18_GRALE
AccessioniPrimary (citable) accession number: Q9ZY18
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 1999
Last sequence update: May 1, 1999
Last modified: May 23, 2018
This is version 88 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health