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Q9ZXB7 (LYS_BPH19) Reviewed, UniProtKB/Swiss-Prot

Last modified October 16, 2013. Version 53. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Lysozyme

EC=3.2.1.17
Alternative name(s):
Endolysin
Lysis protein
Muramidase
Gene names
Name:R
OrganismEnterobacteria phage H19B (Bacteriophage H19B)
Taxonomic identifier69932 [NCBI]
Taxonomic lineageVirusesdsDNA viruses, no RNA stageCaudoviralesSiphoviridaeLambdalikevirusunclassified Lambda-like viruses
Virus hostEscherichia coli [TaxID: 562]

Protein attributes

Sequence length177 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Essential for lysis of bacterial cell wall, by showing cell wall hydrolyzing activity By similarity.

Catalytic activity

Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.

Sequence similarities

Belongs to the glycosyl hydrolase 24 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 177177Lysozyme
PRO_0000218093

Sites

Active site351Proton donor By similarity
Active site441Nucleophile By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9ZXB7 [UniParc].

Last modified May 1, 1999. Version 1.
Checksum: 0041C0E00AAE162E

FASTA17719,506
        10         20         30         40         50         60 
MNAKIRYGLS AAVLALIGAG ASAPEILDQF LDEKEGNHTT AYRDGTGIWT ICRGAILVDG 

        70         80         90        100        110        120 
KPVVPGMKLS KEKCDQVNAI ERDKALAWVE KNIKVPLTDP QKAGIASFCP YNIGPGKCFP 

       130        140        150        160        170 
STFYRRINAG DRRGACEAIR WWIKDGGRDC RIRSNNCYGQ VSRRDQESAL ACWGIDR 

« Hide

References

[1]"Arrangement and functional identification of genes in the regulatory region of lambdoid phage H-19B, a carrier of a shiga-like toxin."
Neely M.N., Friedman D.I.
Gene 223:105-113(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF034975 Genomic DNA. Translation: AAD17382.1.

3D structure databases

ProteinModelPortalQ9ZXB7.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

CAZyGH24. Glycoside Hydrolase Family 24.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D1.10.530.40. 1 hit.
InterProIPR002196. Glyco_hydro_24.
IPR023346. Lysozyme-like_dom.
IPR023347. Lysozyme_dom.
[Graphical view]
PfamPF00959. Phage_lysozyme. 1 hit.
[Graphical view]
SUPFAMSSF53955. SSF53955. 1 hit.
ProtoNetSearch...

Entry information

Entry nameLYS_BPH19
AccessionPrimary (citable) accession number: Q9ZXB7
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: May 1, 1999
Last modified: October 16, 2013
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries