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Protein

AP2/ERF and B3 domain-containing transcription factor RAV1

Gene

RAV1

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Binds specifically to bipartite recognition sequences composed of two unrelated motifs, 5'-CAACA-3' and 5'-CACCTG-3'. May function as negative regulator of plant growth and development.2 Publications

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi61 – 116AP2/ERFPROSITE-ProRule annotationAdd BLAST56
DNA bindingi188 – 292TF-B3PROSITE-ProRule annotationAdd BLAST105

GO - Molecular functioni

  • DNA binding Source: TAIR
  • DNA binding transcription factor activity Source: TAIR

GO - Biological processi

  • ethylene-activated signaling pathway Source: UniProtKB-KW
  • lateral root development Source: TAIR
  • leaf development Source: TAIR
  • negative regulation of flower development Source: TAIR
  • negative regulation of transcription, DNA-templated Source: TAIR
  • response to brassinosteroid Source: TAIR
  • transcription, DNA-templated Source: UniProtKB-KW

Keywordsi

Molecular functionDNA-binding
Biological processEthylene signaling pathway, Transcription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
AP2/ERF and B3 domain-containing transcription factor RAV1
Alternative name(s):
Ethylene-responsive transcription factor RAV1
Protein RELATED TO ABI3/VP1 1
Gene namesi
Name:RAV1
Ordered Locus Names:At1g13260
ORF Names:T6J4.2
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

AraportiAT1G13260
TAIRilocus:2205319 AT1G13260

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001125711 – 344AP2/ERF and B3 domain-containing transcription factor RAV1Add BLAST344

Proteomic databases

PaxDbiQ9ZWM9

PTM databases

iPTMnetiQ9ZWM9

Expressioni

Tissue specificityi

Expressed in all tissues examined: Roots, rosette leaves, cauline leaves, inflorescence stems, flowers and siliques. Highest expression in roots and rosette leaves. Very low expression in flowers.1 Publication

Inductioni

Down-regulated by brassinosteroid and zeatin.1 Publication

Gene expression databases

ExpressionAtlasiQ9ZWM9 baseline and differential
GenevisibleiQ9ZWM9 AT

Interactioni

Subunit structurei

Monomer.

Protein-protein interaction databases

BioGridi23126, 8 interactors
IntActiQ9ZWM9, 8 interactors
STRINGi3702.AT1G13260.1

Structurei

Secondary structure

1344
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi185 – 191Combined sources7
Turni194 – 197Combined sources4
Beta strandi198 – 200Combined sources3
Beta strandi203 – 205Combined sources3
Helixi207 – 210Combined sources4
Turni211 – 213Combined sources3
Beta strandi226 – 232Combined sources7
Turni233 – 235Combined sources3
Beta strandi236 – 245Combined sources10
Turni246 – 249Combined sources4
Beta strandi250 – 256Combined sources7
Helixi257 – 263Combined sources7
Beta strandi271 – 276Combined sources6
Beta strandi279 – 281Combined sources3
Beta strandi284 – 289Combined sources6

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1WIDNMR-A182-298[»]
ProteinModelPortaliQ9ZWM9
SMRiQ9ZWM9
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ9ZWM9

Family & Domainsi

Domaini

Contains two distinct DNA-binding domains. One is located in the N-terminal region and binds to the 5'-CAACA-3' motif. The second is located in the C-terminal region and binds to the 5'-CACCTG-3' motif.

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG410IIT9 Eukaryota
ENOG4110AU5 LUCA
HOGENOMiHOG000237484
KOiK09287
OMAiAVTAREH
OrthoDBiEOG09360IAF
PhylomeDBiQ9ZWM9

Family and domain databases

CDDicd00018 AP2, 1 hit
cd10017 B3_DNA, 1 hit
Gene3Di2.40.330.10, 1 hit
3.30.730.10, 1 hit
InterProiView protein in InterPro
IPR001471 AP2/ERF_dom
IPR036955 AP2/ERF_dom_sf
IPR003340 B3_DNA-bd
IPR016177 DNA-bd_dom_sf
IPR015300 DNA-bd_pseudobarrel_sf
PfamiView protein in Pfam
PF00847 AP2, 1 hit
PF02362 B3, 1 hit
SMARTiView protein in SMART
SM00380 AP2, 1 hit
SM01019 B3, 1 hit
SUPFAMiSSF101936 SSF101936, 1 hit
SSF54171 SSF54171, 1 hit
PROSITEiView protein in PROSITE
PS51032 AP2_ERF, 1 hit
PS50863 B3, 1 hit

Sequencei

Sequence statusi: Complete.

Q9ZWM9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MESSSVDEST TSTGSICETP AITPAKKSSV GNLYRMGSGS SVVLDSENGV
60 70 80 90 100
EAESRKLPSS KYKGVVPQPN GRWGAQIYEK HQRVWLGTFN EEDEAARAYD
110 120 130 140 150
VAVHRFRRRD AVTNFKDVKM DEDEVDFLNS HSKSEIVDML RKHTYNEELE
160 170 180 190 200
QSKRRRNGNG NMTRTLLTSG LSNDGVSTTG FRSAEALFEK AVTPSDVGKL
210 220 230 240 250
NRLVIPKHHA EKHFPLPSSN VSVKGVLLNF EDVNGKVWRF RYSYWNSSQS
260 270 280 290 300
YVLTKGWSRF VKEKNLRAGD VVSFSRSNGQ DQQLYIGWKS RSGSDLDAGR
310 320 330 340
VLRLFGVNIS PESSRNDVVG NKRVNDTEML SLVCSKKQRI FHAS
Length:344
Mass (Da):38,597
Last modified:May 1, 1999 - v1
Checksum:i7349B640B3505823
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB013886 mRNA Translation: BAA34250.1
AC011810 Genomic DNA Translation: AAG09554.1
CP002684 Genomic DNA Translation: AEE28991.1
AY063855 mRNA Translation: AAL36211.1
AY091291 mRNA Translation: AAM14230.1
PIRiT51329
RefSeqiNP_172784.1, NM_101197.4
UniGeneiAt.20558

Genome annotation databases

EnsemblPlantsiAT1G13260.1; AT1G13260.1; AT1G13260
GeneIDi837886
GrameneiAT1G13260.1; AT1G13260.1; AT1G13260
KEGGiath:AT1G13260

Similar proteinsi

Entry informationi

Entry nameiRAV1_ARATH
AccessioniPrimary (citable) accession number: Q9ZWM9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 15, 2002
Last sequence update: May 1, 1999
Last modified: April 25, 2018
This is version 143 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome
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Main funding by: National Institutes of Health