Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q9ZWM9

- RAV1_ARATH

UniProt

Q9ZWM9 - RAV1_ARATH

Protein

AP2/ERF and B3 domain-containing transcription factor RAV1

Gene

RAV1

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 118 (01 Oct 2014)
      Sequence version 1 (01 May 1999)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Binds specifically to bipartite recognition sequences composed of two unrelated motifs, 5'-CAACA-3' and 5'-CACCTG-3'. May function as negative regulator of plant growth and development.2 Publications

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    DNA bindingi61 – 11656AP2/ERFPROSITE-ProRule annotationAdd
    BLAST
    DNA bindingi188 – 292105TF-B3PROSITE-ProRule annotationAdd
    BLAST

    GO - Molecular functioni

    1. DNA binding Source: TAIR
    2. sequence-specific DNA binding transcription factor activity Source: TAIR

    GO - Biological processi

    1. ethylene-activated signaling pathway Source: UniProtKB-KW
    2. lateral root development Source: TAIR
    3. leaf development Source: TAIR
    4. negative regulation of flower development Source: TAIR
    5. negative regulation of transcription, DNA-templated Source: TAIR
    6. response to brassinosteroid Source: TAIR
    7. transcription, DNA-templated Source: UniProtKB-KW

    Keywords - Biological processi

    Ethylene signaling pathway, Transcription, Transcription regulation

    Keywords - Ligandi

    DNA-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    AP2/ERF and B3 domain-containing transcription factor RAV1
    Alternative name(s):
    Ethylene-responsive transcription factor RAV1
    Protein RELATED TO ABI3/VP1 1
    Gene namesi
    Name:RAV1
    Ordered Locus Names:At1g13260
    ORF Names:T6J4.2
    OrganismiArabidopsis thaliana (Mouse-ear cress)
    Taxonomic identifieri3702 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
    ProteomesiUP000006548: Chromosome 1

    Organism-specific databases

    TAIRiAT1G13260.

    Subcellular locationi

    Nucleus Curated

    GO - Cellular componenti

    1. nucleus Source: TAIR

    Keywords - Cellular componenti

    Nucleus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 344344AP2/ERF and B3 domain-containing transcription factor RAV1PRO_0000112571Add
    BLAST

    Proteomic databases

    PRIDEiQ9ZWM9.

    Expressioni

    Tissue specificityi

    Expressed in all tissues examined: Roots, rosette leaves, cauline leaves, inflorescence stems, flowers and siliques. Highest expression in roots and rosette leaves. Very low expression in flowers.1 Publication

    Inductioni

    Down-regulated by brassinosteroid and zeatin.1 Publication

    Gene expression databases

    GenevestigatoriQ9ZWM9.

    Interactioni

    Subunit structurei

    Monomer.

    Protein-protein interaction databases

    BioGridi23126. 5 interactions.
    STRINGi3702.AT1G13260.1-P.

    Structurei

    Secondary structure

    1
    344
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Beta strandi185 – 1917
    Turni194 – 1974
    Beta strandi198 – 2003
    Beta strandi203 – 2053
    Helixi207 – 2104
    Turni211 – 2133
    Beta strandi226 – 2327
    Turni233 – 2353
    Beta strandi236 – 24510
    Turni246 – 2494
    Beta strandi250 – 2567
    Helixi257 – 2637
    Beta strandi271 – 2766
    Beta strandi279 – 2813
    Beta strandi284 – 2896

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    1WIDNMR-A182-298[»]
    ProteinModelPortaliQ9ZWM9.
    SMRiQ9ZWM9. Positions 62-115, 182-298.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiQ9ZWM9.

    Family & Domainsi

    Domaini

    Contains two distinct DNA-binding domains. One is located in the N-terminal region and binds to the 5'-CAACA-3' motif. The second is located in the C-terminal region and binds to the 5'-CACCTG-3' motif.

    Sequence similaritiesi

    Contains 1 AP2/ERF DNA-binding domain.PROSITE-ProRule annotation
    Contains 1 TF-B3 DNA-binding domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiNOG266118.
    HOGENOMiHOG000237484.
    InParanoidiQ9ZWM9.
    KOiK09287.
    OMAiICETPAI.
    PhylomeDBiQ9ZWM9.

    Family and domain databases

    Gene3Di2.40.330.10. 1 hit.
    3.30.730.10. 1 hit.
    InterProiIPR001471. AP2/ERF_dom.
    IPR003340. B3_DNA-bd.
    IPR016177. DNA-bd_dom.
    IPR015300. DNA-bd_pseudobarrel.
    [Graphical view]
    PfamiPF00847. AP2. 1 hit.
    PF02362. B3. 1 hit.
    [Graphical view]
    SMARTiSM00380. AP2. 1 hit.
    SM01019. B3. 1 hit.
    [Graphical view]
    SUPFAMiSSF101936. SSF101936. 1 hit.
    SSF54171. SSF54171. 1 hit.
    PROSITEiPS51032. AP2_ERF. 1 hit.
    PS50863. B3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9ZWM9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MESSSVDEST TSTGSICETP AITPAKKSSV GNLYRMGSGS SVVLDSENGV    50
    EAESRKLPSS KYKGVVPQPN GRWGAQIYEK HQRVWLGTFN EEDEAARAYD 100
    VAVHRFRRRD AVTNFKDVKM DEDEVDFLNS HSKSEIVDML RKHTYNEELE 150
    QSKRRRNGNG NMTRTLLTSG LSNDGVSTTG FRSAEALFEK AVTPSDVGKL 200
    NRLVIPKHHA EKHFPLPSSN VSVKGVLLNF EDVNGKVWRF RYSYWNSSQS 250
    YVLTKGWSRF VKEKNLRAGD VVSFSRSNGQ DQQLYIGWKS RSGSDLDAGR 300
    VLRLFGVNIS PESSRNDVVG NKRVNDTEML SLVCSKKQRI FHAS 344
    Length:344
    Mass (Da):38,597
    Last modified:May 1, 1999 - v1
    Checksum:i7349B640B3505823
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB013886 mRNA. Translation: BAA34250.1.
    AC011810 Genomic DNA. Translation: AAG09554.1.
    CP002684 Genomic DNA. Translation: AEE28991.1.
    AY063855 mRNA. Translation: AAL36211.1.
    AY091291 mRNA. Translation: AAM14230.1.
    PIRiT51329.
    RefSeqiNP_172784.1. NM_101197.3.
    UniGeneiAt.20558.

    Genome annotation databases

    EnsemblPlantsiAT1G13260.1; AT1G13260.1; AT1G13260.
    GeneIDi837886.
    KEGGiath:AT1G13260.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB013886 mRNA. Translation: BAA34250.1 .
    AC011810 Genomic DNA. Translation: AAG09554.1 .
    CP002684 Genomic DNA. Translation: AEE28991.1 .
    AY063855 mRNA. Translation: AAL36211.1 .
    AY091291 mRNA. Translation: AAM14230.1 .
    PIRi T51329.
    RefSeqi NP_172784.1. NM_101197.3.
    UniGenei At.20558.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    1WID NMR - A 182-298 [» ]
    ProteinModelPortali Q9ZWM9.
    SMRi Q9ZWM9. Positions 62-115, 182-298.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 23126. 5 interactions.
    STRINGi 3702.AT1G13260.1-P.

    Proteomic databases

    PRIDEi Q9ZWM9.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi AT1G13260.1 ; AT1G13260.1 ; AT1G13260 .
    GeneIDi 837886.
    KEGGi ath:AT1G13260.

    Organism-specific databases

    TAIRi AT1G13260.

    Phylogenomic databases

    eggNOGi NOG266118.
    HOGENOMi HOG000237484.
    InParanoidi Q9ZWM9.
    KOi K09287.
    OMAi ICETPAI.
    PhylomeDBi Q9ZWM9.

    Miscellaneous databases

    EvolutionaryTracei Q9ZWM9.

    Gene expression databases

    Genevestigatori Q9ZWM9.

    Family and domain databases

    Gene3Di 2.40.330.10. 1 hit.
    3.30.730.10. 1 hit.
    InterProi IPR001471. AP2/ERF_dom.
    IPR003340. B3_DNA-bd.
    IPR016177. DNA-bd_dom.
    IPR015300. DNA-bd_pseudobarrel.
    [Graphical view ]
    Pfami PF00847. AP2. 1 hit.
    PF02362. B3. 1 hit.
    [Graphical view ]
    SMARTi SM00380. AP2. 1 hit.
    SM01019. B3. 1 hit.
    [Graphical view ]
    SUPFAMi SSF101936. SSF101936. 1 hit.
    SSF54171. SSF54171. 1 hit.
    PROSITEi PS51032. AP2_ERF. 1 hit.
    PS50863. B3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "RAV1, a novel DNA-binding protein, binds to bipartite recognition sequence through two distinct DNA-binding domains uniquely found in higher plants."
      Kagaya Y., Ohmiya K., Hattori T.
      Nucleic Acids Res. 27:470-478(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, TISSUE SPECIFICITY.
      Strain: cv. Columbia.
      Tissue: Seedling.
    2. "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana."
      Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K.
      , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.
      Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Columbia.
    3. The Arabidopsis Information Resource (TAIR)
      Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: GENOME REANNOTATION.
      Strain: cv. Columbia.
    4. "Empirical analysis of transcriptional activity in the Arabidopsis genome."
      Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.
      , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
      Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: cv. Columbia.
    5. Cited for: GENE FAMILY.
    6. "Solution structure of the B3 DNA binding domain of the Arabidopsis cold-responsive transcription factor RAV1."
      Yamasaki K., Kigawa T., Inoue M., Tateno M., Yamasaki T., Yabuki T., Aoki M., Seki E., Matsuda T., Tomo Y., Hayami N., Terada T., Shirouzu M., Osanai T., Tanaka A., Seki M., Shinozaki K., Yokoyama S.
      Plant Cell 16:3448-3459(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: STRUCTURE BY NMR OF 182-298.
    7. "Genome-wide analysis of the ERF gene family in Arabidopsis and rice."
      Nakano T., Suzuki K., Fujimura T., Shinshi H.
      Plant Physiol. 140:411-432(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: GENE FAMILY, NOMENCLATURE.
    8. "Arabidopsis RAV1 is down-regulated by brassinosteroid and may act as a negative regulator during plant development."
      Hu Y.X., Wang Y.H., Liu X.F., Li J.Y.
      Cell Res. 14:8-15(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION, INDUCTION.

    Entry informationi

    Entry nameiRAV1_ARATH
    AccessioniPrimary (citable) accession number: Q9ZWM9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 15, 2002
    Last sequence update: May 1, 1999
    Last modified: October 1, 2014
    This is version 118 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    3D-structure, Complete proteome, Reference proteome

    Documents

    1. Arabidopsis thaliana
      Arabidopsis thaliana: entries and gene names
    2. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3