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Q9ZW30

- GSTU1_ARATH

UniProt

Q9ZW30 - GSTU1_ARATH

Protein

Glutathione S-transferase U1

Gene

GSTU1

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 103 (01 Oct 2014)
      Sequence version 1 (01 May 1999)
      Previous versions | rss
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    Functioni

    May be involved in the conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles and have a detoxification role against certain herbicides.By similarity

    Catalytic activityi

    RX + glutathione = HX + R-S-glutathione.

    GO - Molecular functioni

    1. glutathione transferase activity Source: UniProtKB-EC

    GO - Biological processi

    1. response to stress Source: UniProtKB-KW
    2. response to toxic substance Source: UniProtKB-KW
    3. toxin catabolic process Source: TAIR

    Keywords - Molecular functioni

    Transferase

    Keywords - Biological processi

    Detoxification, Stress response

    Enzyme and pathway databases

    BioCyciARA:AT2G29490-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glutathione S-transferase U1 (EC:2.5.1.18)
    Short name:
    AtGSTU1
    Alternative name(s):
    GST class-tau member 1
    Glutathione S-transferase 19
    Gene namesi
    Name:GSTU1
    Synonyms:GST19
    Ordered Locus Names:At2g29490
    ORF Names:F16P2.13
    OrganismiArabidopsis thaliana (Mouse-ear cress)
    Taxonomic identifieri3702 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
    ProteomesiUP000006548: Chromosome 2

    Organism-specific databases

    TAIRiAT2G29490.

    Subcellular locationi

    Cytoplasmcytosol Curated

    GO - Cellular componenti

    1. cytoplasm Source: TAIR
    2. cytosol Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 224224Glutathione S-transferase U1PRO_0000413548Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei151 – 1511PhosphothreonineBy similarity

    Keywords - PTMi

    Phosphoprotein

    Proteomic databases

    PaxDbiQ9ZW30.
    PRIDEiQ9ZW30.

    Expressioni

    Inductioni

    By acetochlor, metolachlor and 2,4,6-trinitrotoluene (TNT).1 Publication

    Gene expression databases

    GenevestigatoriQ9ZW30.

    Interactioni

    Protein-protein interaction databases

    BioGridi2848. 6 interactions.
    IntActiQ9ZW30. 6 interactions.
    STRINGi3702.AT2G29490.1-P.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9ZW30.
    SMRiQ9ZW30. Positions 6-221.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini6 – 8580GST N-terminalAdd
    BLAST
    Domaini90 – 217128GST C-terminalAdd
    BLAST

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni16 – 172Glutathione bindingBy similarity
    Regioni42 – 432Glutathione bindingBy similarity
    Regioni56 – 572Glutathione bindingBy similarity
    Regioni69 – 702Glutathione bindingBy similarity

    Sequence similaritiesi

    Belongs to the GST superfamily. Tau family.Curated
    Contains 1 GST C-terminal domain.Curated
    Contains 1 GST N-terminal domain.Curated

    Phylogenomic databases

    eggNOGiCOG0625.
    HOGENOMiHOG000125749.
    InParanoidiQ9ZW30.
    KOiK00799.
    OMAiFSEAKPR.
    PhylomeDBiQ9ZW30.

    Family and domain databases

    Gene3Di1.20.1050.10. 1 hit.
    3.40.30.10. 1 hit.
    InterProiIPR010987. Glutathione-S-Trfase_C-like.
    IPR004045. Glutathione_S-Trfase_N.
    IPR004046. GST_C.
    IPR012336. Thioredoxin-like_fold.
    [Graphical view]
    PfamiPF14497. GST_C_3. 1 hit.
    PF13417. GST_N_3. 1 hit.
    [Graphical view]
    SUPFAMiSSF47616. SSF47616. 1 hit.
    SSF52833. SSF52833. 1 hit.
    PROSITEiPS50405. GST_CTER. 1 hit.
    PS50404. GST_NTER. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9ZW30-1 [UniParc]FASTAAdd to Basket

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    MAEKEESVKL LGFWASPFSR RVEMALKLKG VPYEYLEEDL PNKTPLLLEL    50
    NPLHKKVPVL VHNDKILLES HLILEYIDQT WKNSPILPQD PYEKAMARFW 100
    AKFIDDQILT LGFRSLVKAE KGREVAIEET RELLMFLEKE VTGKDFFGGK 150
    TIGFLDMIAG SMIPFCLARL WKGIGIDMIP EEKFPELNRW IKNLEEVEAV 200
    RGCIPPREKQ IERMTKIAET IKSA 224
    Length:224
    Mass (Da):25,914
    Last modified:May 1, 1999 - v1
    Checksum:i5BD722371683FED8
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF288183 mRNA. Translation: AAG30132.1.
    AC004561 Genomic DNA. Translation: AAC95189.1.
    CP002685 Genomic DNA. Translation: AEC08260.1.
    AF428387 mRNA. Translation: AAL16155.1.
    BT010162 mRNA. Translation: AAQ22631.1.
    PIRiA84697.
    RefSeqiNP_180510.1. NM_128503.2.
    UniGeneiAt.20874.

    Genome annotation databases

    EnsemblPlantsiAT2G29490.1; AT2G29490.1; AT2G29490.
    GeneIDi817498.
    KEGGiath:AT2G29490.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF288183 mRNA. Translation: AAG30132.1 .
    AC004561 Genomic DNA. Translation: AAC95189.1 .
    CP002685 Genomic DNA. Translation: AEC08260.1 .
    AF428387 mRNA. Translation: AAL16155.1 .
    BT010162 mRNA. Translation: AAQ22631.1 .
    PIRi A84697.
    RefSeqi NP_180510.1. NM_128503.2.
    UniGenei At.20874.

    3D structure databases

    ProteinModelPortali Q9ZW30.
    SMRi Q9ZW30. Positions 6-221.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 2848. 6 interactions.
    IntActi Q9ZW30. 6 interactions.
    STRINGi 3702.AT2G29490.1-P.

    Proteomic databases

    PaxDbi Q9ZW30.
    PRIDEi Q9ZW30.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi AT2G29490.1 ; AT2G29490.1 ; AT2G29490 .
    GeneIDi 817498.
    KEGGi ath:AT2G29490.

    Organism-specific databases

    TAIRi AT2G29490.

    Phylogenomic databases

    eggNOGi COG0625.
    HOGENOMi HOG000125749.
    InParanoidi Q9ZW30.
    KOi K00799.
    OMAi FSEAKPR.
    PhylomeDBi Q9ZW30.

    Enzyme and pathway databases

    BioCyci ARA:AT2G29490-MONOMER.

    Gene expression databases

    Genevestigatori Q9ZW30.

    Family and domain databases

    Gene3Di 1.20.1050.10. 1 hit.
    3.40.30.10. 1 hit.
    InterProi IPR010987. Glutathione-S-Trfase_C-like.
    IPR004045. Glutathione_S-Trfase_N.
    IPR004046. GST_C.
    IPR012336. Thioredoxin-like_fold.
    [Graphical view ]
    Pfami PF14497. GST_C_3. 1 hit.
    PF13417. GST_N_3. 1 hit.
    [Graphical view ]
    SUPFAMi SSF47616. SSF47616. 1 hit.
    SSF52833. SSF52833. 1 hit.
    PROSITEi PS50405. GST_CTER. 1 hit.
    PS50404. GST_NTER. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Probing the diversity of the Arabidopsis glutathione S-transferase gene family."
      Wagner U., Edwards R., Dixon D.P., Mauch F.
      Plant Mol. Biol. 49:515-532(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA], GENE FAMILY, NOMENCLATURE.
      Strain: cv. Columbia.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Columbia.
    3. The Arabidopsis Information Resource (TAIR)
      Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: GENOME REANNOTATION.
      Strain: cv. Columbia.
    4. "Empirical analysis of transcriptional activity in the Arabidopsis genome."
      Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.
      , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
      Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: cv. Columbia.
    5. "Gene expression and microscopic analysis of Arabidopsis exposed to chloroacetanilide herbicides and explosive compounds. A phytoremediation approach."
      Mezzari M.P., Walters K., Jelinkova M., Shih M.C., Just C.L., Schnoor J.L.
      Plant Physiol. 138:858-869(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: INDUCTION.

    Entry informationi

    Entry nameiGSTU1_ARATH
    AccessioniPrimary (citable) accession number: Q9ZW30
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 19, 2011
    Last sequence update: May 1, 1999
    Last modified: October 1, 2014
    This is version 103 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Arabidopsis thaliana
      Arabidopsis thaliana: entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3