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Protein

Glutathione S-transferase U3

Gene

GSTU3

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

May be involved in the conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles and have a detoxification role against certain herbicides.By similarity

Catalytic activityi

RX + glutathione = HX + R-S-glutathione.

GO - Molecular functioni

GO - Biological processi

  • glutathione metabolic process Source: GO_Central
  • toxin catabolic process Source: TAIR

Keywordsi

Molecular functionTransferase
Biological processDetoxification

Enzyme and pathway databases

BioCyciARA:AT2G29470-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Glutathione S-transferase U3 (EC:2.5.1.18)
Short name:
AtGSTU3
Alternative name(s):
GST class-tau member 3
Glutathione S-transferase 21
Gene namesi
Name:GSTU3
Synonyms:GST21
Ordered Locus Names:At2g29470
ORF Names:F16P2.15
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 2

Organism-specific databases

AraportiAT2G29470
TAIRilocus:2043007 AT2G29470

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004135501 – 225Glutathione S-transferase U3Add BLAST225

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei152PhosphothreonineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ9ZW28
PRIDEiQ9ZW28

Expressioni

Gene expression databases

ExpressionAtlasiQ9ZW28 baseline and differential
GenevisibleiQ9ZW28 AT

Interactioni

Protein-protein interaction databases

STRINGi3702.AT2G29470.1

Structurei

3D structure databases

ProteinModelPortaliQ9ZW28
SMRiQ9ZW28
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini6 – 86GST N-terminalAdd BLAST81
Domaini91 – 218GST C-terminalAdd BLAST128

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni16 – 17Glutathione bindingBy similarity2
Regioni43 – 44Glutathione bindingBy similarity2
Regioni57 – 58Glutathione bindingBy similarity2
Regioni70 – 71Glutathione bindingBy similarity2

Sequence similaritiesi

Belongs to the GST superfamily. Tau family.Curated

Phylogenomic databases

eggNOGiKOG0406 Eukaryota
ENOG410XSIX LUCA
HOGENOMiHOG000125749
InParanoidiQ9ZW28
KOiK00799
OMAiQEAIGME
OrthoDBiEOG09360KSR
PhylomeDBiQ9ZW28

Family and domain databases

InterProiView protein in InterPro
IPR010987 Glutathione-S-Trfase_C-like
IPR036282 Glutathione-S-Trfase_C_sf
IPR004045 Glutathione_S-Trfase_N
IPR036249 Thioredoxin-like_sf
PfamiView protein in Pfam
PF13417 GST_N_3, 1 hit
SUPFAMiSSF47616 SSF47616, 1 hit
SSF52833 SSF52833, 1 hit
PROSITEiView protein in PROSITE
PS50405 GST_CTER, 1 hit
PS50404 GST_NTER, 1 hit

Sequencei

Sequence statusi: Complete.

Q9ZW28-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAEKEEGVKL IGSWASPFSR RVEMALKLKG VPYDYLDEDY LVVKSPLLLQ
60 70 80 90 100
LNPVYKKVPV LVHNGKILPE SQLILEYIDQ TWTNNPILPQ SPYDKAMARF
110 120 130 140 150
WAKFVDEQVT MIGLRSLVKS EKRIDVAIEE VQELIMLLEN QITGKKLFGG
160 170 180 190 200
ETIGFLDMVV GSMIPFCLAR AWEGMGIDMI PEEKFPELNR WIKNLKEIEI
210 220
VRECIPDREK HIEHMMKIVG RIKAV
Length:225
Mass (Da):25,941
Last modified:May 1, 1999 - v1
Checksum:i612AD3270285CD03
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF288185 mRNA Translation: AAG30134.1
AC004561 Genomic DNA Translation: AAC95191.1
CP002685 Genomic DNA Translation: AEC08258.1
AK117612 mRNA Translation: BAC42268.1
PIRiG84696
RefSeqiNP_180508.1, NM_128501.4
UniGeneiAt.12689

Genome annotation databases

EnsemblPlantsiAT2G29470.1; AT2G29470.1; AT2G29470
GeneIDi817496
GrameneiAT2G29470.1; AT2G29470.1; AT2G29470
KEGGiath:AT2G29470

Similar proteinsi

Entry informationi

Entry nameiGSTU3_ARATH
AccessioniPrimary (citable) accession number: Q9ZW28
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 19, 2011
Last sequence update: May 1, 1999
Last modified: May 23, 2018
This is version 120 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

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