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Q9ZW28 (GSTU3_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified March 19, 2014. Version 94. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutathione S-transferase U3

Short name=AtGSTU3
EC=2.5.1.18
Alternative name(s):
GST class-tau member 3
Glutathione S-transferase 21
Gene names
Name:GSTU3
Synonyms:GST21
Ordered Locus Names:At2g29470
ORF Names:F16P2.15
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Protein attributes

Sequence length225 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

May be involved in the conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles and have a detoxification role against certain herbicides By similarity.

Catalytic activity

RX + glutathione = HX + R-S-glutathione.

Subcellular location

Cytoplasmcytosol Probable.

Sequence similarities

Belongs to the GST superfamily. Tau family.

Contains 1 GST C-terminal domain.

Contains 1 GST N-terminal domain.

Ontologies

Keywords
   Biological processDetoxification
   Cellular componentCytoplasm
   Molecular functionTransferase
   PTMPhosphoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processresponse to toxic substance

Inferred from electronic annotation. Source: UniProtKB-KW

toxin catabolic process

Traceable author statement Ref.1. Source: TAIR

   Cellular_componentcytoplasm

Non-traceable author statement Ref.1. Source: TAIR

cytosol

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglutathione transferase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 225225Glutathione S-transferase U3
PRO_0000413550

Regions

Domain6 – 8681GST N-terminal
Domain91 – 218128GST C-terminal
Region16 – 172Glutathione binding By similarity
Region43 – 442Glutathione binding By similarity
Region57 – 582Glutathione binding By similarity
Region70 – 712Glutathione binding By similarity

Amino acid modifications

Modified residue1521Phosphothreonine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9ZW28 [UniParc].

Last modified May 1, 1999. Version 1.
Checksum: 612AD3270285CD03

FASTA22525,941
        10         20         30         40         50         60 
MAEKEEGVKL IGSWASPFSR RVEMALKLKG VPYDYLDEDY LVVKSPLLLQ LNPVYKKVPV 

        70         80         90        100        110        120 
LVHNGKILPE SQLILEYIDQ TWTNNPILPQ SPYDKAMARF WAKFVDEQVT MIGLRSLVKS 

       130        140        150        160        170        180 
EKRIDVAIEE VQELIMLLEN QITGKKLFGG ETIGFLDMVV GSMIPFCLAR AWEGMGIDMI 

       190        200        210        220 
PEEKFPELNR WIKNLKEIEI VRECIPDREK HIEHMMKIVG RIKAV 

« Hide

References

« Hide 'large scale' references
[1]"Probing the diversity of the Arabidopsis glutathione S-transferase gene family."
Wagner U., Edwards R., Dixon D.P., Mauch F.
Plant Mol. Biol. 49:515-532(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA], GENE FAMILY, NOMENCLATURE.
Strain: cv. Columbia.
[2]"Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana."
Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D., Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V., Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S., Cronin L.A. expand/collapse author list , Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J., Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M., Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O., Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.
Nature 402:761-768(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[3]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[4]"Functional annotation of a full-length Arabidopsis cDNA collection."
Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T., Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y., Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K., Shinagawa A., Shinozaki K.
Science 296:141-145(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF288185 mRNA. Translation: AAG30134.1.
AC004561 Genomic DNA. Translation: AAC95191.1.
CP002685 Genomic DNA. Translation: AEC08258.1.
AK117612 mRNA. Translation: BAC42268.1.
PIRG84696.
RefSeqNP_180508.1. NM_128501.3.
UniGeneAt.12689.

3D structure databases

ProteinModelPortalQ9ZW28.
SMRQ9ZW28. Positions 6-210.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING3702.AT2G29470.1-P.

Proteomic databases

PaxDbQ9ZW28.
PRIDEQ9ZW28.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT2G29470.1; AT2G29470.1; AT2G29470.
GeneID817496.
KEGGath:AT2G29470.

Organism-specific databases

TAIRAT2G29470.

Phylogenomic databases

eggNOGNOG274516.
HOGENOMHOG000125749.
InParanoidQ9ZW28.
KOK00799.
OMAVKSEKRI.
PhylomeDBQ9ZW28.
ProtClustDBCLSN2683712.

Enzyme and pathway databases

BioCycARA:AT2G29470-MONOMER.

Gene expression databases

GenevestigatorQ9ZW28.

Family and domain databases

Gene3D1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProIPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamPF13417. GST_N_3. 1 hit.
[Graphical view]
SUPFAMSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEPS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGSTU3_ARATH
AccessionPrimary (citable) accession number: Q9ZW28
Entry history
Integrated into UniProtKB/Swiss-Prot: October 19, 2011
Last sequence update: May 1, 1999
Last modified: March 19, 2014
This is version 94 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names