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Q9ZW26 (GSTU6_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified March 19, 2014. Version 91. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutathione S-transferase U6

Short name=AtGSTU6
EC=2.5.1.18
Alternative name(s):
GST class-tau member 6
Glutathione S-transferase 24
Gene names
Name:GSTU6
Synonyms:GST24
Ordered Locus Names:At2g29440
ORF Names:F16P2.18
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Protein attributes

Sequence length223 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

May be involved in the conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles and have a detoxification role against certain herbicides By similarity.

Catalytic activity

RX + glutathione = HX + R-S-glutathione.

Subcellular location

Cytoplasmcytosol Probable.

Sequence similarities

Belongs to the GST superfamily. Tau family.

Contains 1 GST C-terminal domain.

Contains 1 GST N-terminal domain.

Ontologies

Keywords
   Biological processDetoxification
   Cellular componentCytoplasm
   Molecular functionTransferase
   PTMPhosphoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processresponse to toxic substance

Inferred from electronic annotation. Source: UniProtKB-KW

toxin catabolic process

Traceable author statement Ref.1. Source: TAIR

   Cellular_componentcytosol

Inferred from direct assay PubMed 21166475. Source: TAIR

   Molecular_functionglutathione transferase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 223223Glutathione S-transferase U6
PRO_0000413552

Regions

Domain5 – 8480GST N-terminal
Domain89 – 216128GST C-terminal
Region15 – 162Glutathione binding By similarity
Region41 – 422Glutathione binding By similarity
Region55 – 562Glutathione binding By similarity
Region68 – 692Glutathione binding By similarity

Amino acid modifications

Modified residue1501Phosphothreonine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9ZW26 [UniParc].

Last modified May 1, 1999. Version 1.
Checksum: AD15D4CD0C91B95F

FASTA22325,618
        10         20         30         40         50         60 
MGKNEEVKLL GIWASPFSRR IEMALKLKGV PYEYLEEDLE NKSSLLLALS PIHKKIPVLV 

        70         80         90        100        110        120 
HNGKTIIESH VILEYIDETW KHNPILPQDP FQRSKARVLA KLVDEKIVNV GFASLAKTEK 

       130        140        150        160        170        180 
GREVLIEQTR ELIMCLEKEL AGKDYFGGKT VGFLDFVAGS MIPFCLERAW EGMGVEMITE 

       190        200        210        220 
KKFPEYNKWV KKLKEVEIVV DCIPLREKHI EHMNNMAEKI RSA 

« Hide

References

« Hide 'large scale' references
[1]"Probing the diversity of the Arabidopsis glutathione S-transferase gene family."
Wagner U., Edwards R., Dixon D.P., Mauch F.
Plant Mol. Biol. 49:515-532(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA], GENE FAMILY, NOMENCLATURE.
Strain: cv. Columbia.
[2]"Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana."
Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D., Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V., Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S., Cronin L.A. expand/collapse author list , Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J., Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M., Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O., Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.
Nature 402:761-768(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[3]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[4]"Arabidopsis ORF clones."
Kim C.J., Chen H., Shinn P., Ecker J.R.
Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
[5]"Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs."
Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A., Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y., Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K. expand/collapse author list , Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y., Shinozaki K.
Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF288187 mRNA. Translation: AAG30136.1.
AC004561 Genomic DNA. Translation: AAC95194.1.
CP002685 Genomic DNA. Translation: AEC08254.1.
BT024843 mRNA. Translation: ABD60726.1.
AK229012 mRNA. Translation: BAF00899.1.
PIRD84696.
RefSeqNP_180505.1. NM_128498.4.
UniGeneAt.12687.

3D structure databases

ProteinModelPortalQ9ZW26.
SMRQ9ZW26. Positions 5-208.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING3702.AT2G29440.1-P.

Proteomic databases

PaxDbQ9ZW26.
PRIDEQ9ZW26.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT2G29440.1; AT2G29440.1; AT2G29440.
GeneID817493.
KEGGath:AT2G29440.

Organism-specific databases

TAIRAT2G29440.

Phylogenomic databases

eggNOGCOG0625.
HOGENOMHOG000125749.
InParanoidQ9ZW26.
KOK00799.
OMARIEMALK.
PhylomeDBQ9ZW26.
ProtClustDBCLSN2913215.

Enzyme and pathway databases

BioCycARA:AT2G29440-MONOMER.

Gene expression databases

GenevestigatorQ9ZW26.

Family and domain databases

Gene3D1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProIPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamPF13417. GST_N_3. 1 hit.
[Graphical view]
SUPFAMSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEPS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGSTU6_ARATH
AccessionPrimary (citable) accession number: Q9ZW26
Entry history
Integrated into UniProtKB/Swiss-Prot: October 19, 2011
Last sequence update: May 1, 1999
Last modified: March 19, 2014
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names