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Protein

Glutathione S-transferase U7

Gene

GSTU7

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

May be involved in the conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles and have a detoxification role against certain herbicides.By similarity

Catalytic activityi

RX + glutathione = HX + R-S-glutathione.

GO - Molecular functioni

  • glutathione transferase activity Source: TAIR

GO - Biological processi

  • response to salicylic acid Source: TAIR
  • response to toxic substance Source: UniProtKB-KW
  • toxin catabolic process Source: TAIR
Complete GO annotation...

Keywords - Molecular functioni

Transferase

Keywords - Biological processi

Detoxification

Enzyme and pathway databases

BioCyciARA:AT2G29420-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutathione S-transferase U7 (EC:2.5.1.18)
Short name:
AtGSTU7
Alternative name(s):
GST class-tau member 7
Glutathione S-transferase 25
Gene namesi
Name:GSTU7
Synonyms:GST25
Ordered Locus Names:At2g29420
ORF Names:F16P2.20
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
ProteomesiUP000006548 Componenti: Chromosome 2

Organism-specific databases

TAIRiAT2G29420.

Subcellular locationi

GO - Cellular componenti

  • cytoplasm Source: TAIR
  • cytosol Source: TAIR
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 227227Glutathione S-transferase U7PRO_0000413553Add
BLAST

Proteomic databases

PaxDbiQ9ZW24.
PRIDEiQ9ZW24.

Interactioni

Protein-protein interaction databases

BioGridi2841. 4 interactions.
IntActiQ9ZW24. 4 interactions.
STRINGi3702.AT2G29420.1.

Structurei

3D structure databases

ProteinModelPortaliQ9ZW24.
SMRiQ9ZW24. Positions 8-222.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini8 – 8780GST N-terminalAdd
BLAST
Domaini92 – 215124GST C-terminalAdd
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni18 – 192Glutathione bindingBy similarity
Regioni44 – 452Glutathione bindingBy similarity
Regioni58 – 592Glutathione bindingBy similarity
Regioni71 – 722Glutathione bindingBy similarity

Sequence similaritiesi

Belongs to the GST superfamily. Tau family.Curated
Contains 1 GST C-terminal domain.Curated
Contains 1 GST N-terminal domain.Curated

Phylogenomic databases

eggNOGiCOG0625.
HOGENOMiHOG000125749.
InParanoidiQ9ZW24.
KOiK00799.
OMAiYERTMAR.
PhylomeDBiQ9ZW24.

Family and domain databases

Gene3Di1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProiIPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR004046. GST_C.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamiPF00043. GST_C. 1 hit.
PF13417. GST_N_3. 1 hit.
[Graphical view]
SUPFAMiSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEiPS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9ZW24-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAERSNSEEV KLLGMWASPF SRRIEIALTL KGVSYEFLEQ DITNKSSLLL
60 70 80 90 100
QLNPVHKMIP VLVHNGKPIS ESLVILEYID ETWRDNPILP QDPYERTMAR
110 120 130 140 150
FWSKFVDEQI YVTAMKVVGK TGKERDAVVE ATRDLLMFLE KELVGKDFLG
160 170 180 190 200
GKSLGFVDIV ATLVAFWLMR TEEIVGVKVV PVEKFPEIHR WVKNLLGNDV
210 220
IKKCIPPEDE HLKYIRARME KLNIKSA
Length:227
Mass (Da):26,113
Last modified:May 1, 1999 - v1
Checksum:iFE3DC828644E0999
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF288188 mRNA. Translation: AAG30137.1.
AC004561 Genomic DNA. Translation: AAC95196.1.
CP002685 Genomic DNA. Translation: AEC08252.1.
AY045679 mRNA. Translation: AAK74037.1.
AY056086 mRNA. Translation: AAL06974.1.
AY086358 mRNA. Translation: AAM64426.1.
PIRiB84696.
RefSeqiNP_180503.1. NM_128496.2.
UniGeneiAt.20452.

Genome annotation databases

EnsemblPlantsiAT2G29420.1; AT2G29420.1; AT2G29420.
GeneIDi817491.
KEGGiath:AT2G29420.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF288188 mRNA. Translation: AAG30137.1.
AC004561 Genomic DNA. Translation: AAC95196.1.
CP002685 Genomic DNA. Translation: AEC08252.1.
AY045679 mRNA. Translation: AAK74037.1.
AY056086 mRNA. Translation: AAL06974.1.
AY086358 mRNA. Translation: AAM64426.1.
PIRiB84696.
RefSeqiNP_180503.1. NM_128496.2.
UniGeneiAt.20452.

3D structure databases

ProteinModelPortaliQ9ZW24.
SMRiQ9ZW24. Positions 8-222.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi2841. 4 interactions.
IntActiQ9ZW24. 4 interactions.
STRINGi3702.AT2G29420.1.

Proteomic databases

PaxDbiQ9ZW24.
PRIDEiQ9ZW24.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT2G29420.1; AT2G29420.1; AT2G29420.
GeneIDi817491.
KEGGiath:AT2G29420.

Organism-specific databases

TAIRiAT2G29420.

Phylogenomic databases

eggNOGiCOG0625.
HOGENOMiHOG000125749.
InParanoidiQ9ZW24.
KOiK00799.
OMAiYERTMAR.
PhylomeDBiQ9ZW24.

Enzyme and pathway databases

BioCyciARA:AT2G29420-MONOMER.

Miscellaneous databases

PROiQ9ZW24.

Family and domain databases

Gene3Di1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProiIPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR004046. GST_C.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamiPF00043. GST_C. 1 hit.
PF13417. GST_N_3. 1 hit.
[Graphical view]
SUPFAMiSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEiPS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Probing the diversity of the Arabidopsis glutathione S-transferase gene family."
    Wagner U., Edwards R., Dixon D.P., Mauch F.
    Plant Mol. Biol. 49:515-532(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA], GENE FAMILY, NOMENCLATURE.
    Strain: cv. Columbia.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  3. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  4. "Empirical analysis of transcriptional activity in the Arabidopsis genome."
    Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.
    , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
    Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Columbia.
  5. "Full-length cDNA from Arabidopsis thaliana."
    Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B., Feldmann K.A.
    Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].

Entry informationi

Entry nameiGSTU7_ARATH
AccessioniPrimary (citable) accession number: Q9ZW24
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 19, 2011
Last sequence update: May 1, 1999
Last modified: July 22, 2015
This is version 106 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.