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Protein

Probable protein phosphatase 2C 24

Gene

At2g29380

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Mg2+By similarity, Mn2+By similarityNote: Binds 2 magnesium or manganese ions per subunit.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi117 – 1171Manganese 1By similarity
Metal bindingi117 – 1171Manganese 2By similarity
Metal bindingi118 – 1181Manganese 1; via carbonyl oxygenBy similarity
Metal bindingi295 – 2951Manganese 2By similarity
Metal bindingi351 – 3511Manganese 2By similarity

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. protein serine/threonine phosphatase activity Source: InterPro

GO - Biological processi

  1. protein dephosphorylation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Ligandi

Magnesium, Manganese, Metal-binding

Enzyme and pathway databases

BioCyciARA:AT2G29380-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable protein phosphatase 2C 24 (EC:3.1.3.16)
Short name:
AtPP2C24
Gene namesi
Ordered Locus Names:At2g29380
ORF Names:F16P2.24
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
ProteomesiUP000006548: Chromosome 2

Organism-specific databases

TAIRiAT2G29380.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 362362Probable protein phosphatase 2C 24PRO_0000367953Add
BLAST

Proteomic databases

PRIDEiQ9ZW21.

Expressioni

Gene expression databases

GenevestigatoriQ9ZW21.

Interactioni

Protein-protein interaction databases

BioGridi2837. 6 interactions.
DIPiDIP-48991N.
IntActiQ9ZW21. 1 interaction.
STRINGi3702.AT2G29380.1-P.

Structurei

3D structure databases

ProteinModelPortaliQ9ZW21.
SMRiQ9ZW21. Positions 76-361.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini76 – 353278PP2C-likeAdd
BLAST

Sequence similaritiesi

Belongs to the PP2C family.Curated
Contains 1 PP2C-like domain.Curated

Phylogenomic databases

eggNOGiCOG0631.
HOGENOMiHOG000233896.
InParanoidiQ9ZW21.
KOiK14497.
OMAiNCRCEMQ.
PhylomeDBiQ9ZW21.

Family and domain databases

Gene3Di3.60.40.10. 1 hit.
InterProiIPR001932. PP2C-like_dom.
IPR000222. PP2C_Mn2_Asp60_BS.
IPR015655. Protein_Pase_2C.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 1 hit.
PfamiPF00481. PP2C. 1 hit.
[Graphical view]
SMARTiSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 1 hit.
PROSITEiPS01032. PP2C. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9ZW21-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAEICYEVVT DACPSSVYES TPAHSRRRPR FQTVMHEDWE KNCKRSKQEA
60 70 80 90 100
LATRYSSIPR SSREDFSDQN VDVSSPRYGV SSVCGRRREM EDAVAIHPSF
110 120 130 140 150
SSPKNSEFPQ HYFGVYDGHG CSHVAARCRE RLHKLVQEEL SSDMEDEEEW
160 170 180 190 200
KTTMERSFTR MDKEVVSWGD SVVTANCKCD LQTPACDSVG STAVVSVITP
210 220 230 240 250
DKIVVANCGD SRAVLCRNGK PVPLSTDHKP DRPDELDRIE GAGGRVIYWD
260 270 280 290 300
CPRVLGVLAM SRAIGDNYLK PYVSCEPEVT ITDRRDDDCL ILASDGLWDV
310 320 330 340 350
VSNETACSVA RMCLRGGGRR QDNEDPAISD KACTEASVLL TKLALARNSS
360
DNVSVVVIDL RR
Length:362
Mass (Da):40,297
Last modified:May 1, 1999 - v1
Checksum:iD127B5057DA3E0D4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC004561 Genomic DNA. Translation: AAC95200.1.
CP002685 Genomic DNA. Translation: AEC08244.1.
DQ056553 mRNA. Translation: AAY78704.1.
BT022047 mRNA. Translation: AAY25459.1.
BT023483 mRNA. Translation: AAY57322.1.
PIRiF84695.
RefSeqiNP_180499.1. NM_128492.2.
UniGeneiAt.50109.

Genome annotation databases

EnsemblPlantsiAT2G29380.1; AT2G29380.1; AT2G29380.
GeneIDi817487.
KEGGiath:AT2G29380.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC004561 Genomic DNA. Translation: AAC95200.1.
CP002685 Genomic DNA. Translation: AEC08244.1.
DQ056553 mRNA. Translation: AAY78704.1.
BT022047 mRNA. Translation: AAY25459.1.
BT023483 mRNA. Translation: AAY57322.1.
PIRiF84695.
RefSeqiNP_180499.1. NM_128492.2.
UniGeneiAt.50109.

3D structure databases

ProteinModelPortaliQ9ZW21.
SMRiQ9ZW21. Positions 76-361.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi2837. 6 interactions.
DIPiDIP-48991N.
IntActiQ9ZW21. 1 interaction.
STRINGi3702.AT2G29380.1-P.

Proteomic databases

PRIDEiQ9ZW21.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT2G29380.1; AT2G29380.1; AT2G29380.
GeneIDi817487.
KEGGiath:AT2G29380.

Organism-specific databases

TAIRiAT2G29380.

Phylogenomic databases

eggNOGiCOG0631.
HOGENOMiHOG000233896.
InParanoidiQ9ZW21.
KOiK14497.
OMAiNCRCEMQ.
PhylomeDBiQ9ZW21.

Enzyme and pathway databases

BioCyciARA:AT2G29380-MONOMER.

Gene expression databases

GenevestigatoriQ9ZW21.

Family and domain databases

Gene3Di3.60.40.10. 1 hit.
InterProiIPR001932. PP2C-like_dom.
IPR000222. PP2C_Mn2_Asp60_BS.
IPR015655. Protein_Pase_2C.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 1 hit.
PfamiPF00481. PP2C. 1 hit.
[Graphical view]
SMARTiSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 1 hit.
PROSITEiPS01032. PP2C. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  2. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  3. Underwood B.A., Xiao Y.-L., Moskal W.A. Jr., Monaghan E.L., Wang W., Redman J.C., Wu H.C., Utterback T., Town C.D.
    Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Columbia.
  4. "Arabidopsis ORF clones."
    Kim C.J., Chen H., Cheuk R.F., Shinn P., Ecker J.R.
    Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Columbia.
  5. "Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis."
    Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y.
    BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY, NOMENCLATURE.

Entry informationi

Entry nameiP2C24_ARATH
AccessioniPrimary (citable) accession number: Q9ZW21
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: May 1, 1999
Last modified: February 4, 2015
This is version 101 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.