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Q9ZW21

- P2C24_ARATH

UniProt

Q9ZW21 - P2C24_ARATH

Protein

Probable protein phosphatase 2C 24

Gene

At2g29380

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 98 (01 Oct 2014)
      Sequence version 1 (01 May 1999)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    [a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

    Cofactori

    Binds 2 magnesium or manganese ions per subunit.By similarity

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi117 – 1171Manganese 1By similarity
    Metal bindingi117 – 1171Manganese 2By similarity
    Metal bindingi118 – 1181Manganese 1; via carbonyl oxygenBy similarity
    Metal bindingi295 – 2951Manganese 2By similarity
    Metal bindingi351 – 3511Manganese 2By similarity

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. protein serine/threonine phosphatase activity Source: InterPro

    GO - Biological processi

    1. protein dephosphorylation Source: InterPro

    Keywords - Molecular functioni

    Hydrolase, Protein phosphatase

    Keywords - Ligandi

    Magnesium, Manganese, Metal-binding

    Enzyme and pathway databases

    BioCyciARA:AT2G29380-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable protein phosphatase 2C 24 (EC:3.1.3.16)
    Short name:
    AtPP2C24
    Gene namesi
    Ordered Locus Names:At2g29380
    ORF Names:F16P2.24
    OrganismiArabidopsis thaliana (Mouse-ear cress)
    Taxonomic identifieri3702 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
    ProteomesiUP000006548: Chromosome 2

    Organism-specific databases

    TAIRiAT2G29380.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 362362Probable protein phosphatase 2C 24PRO_0000367953Add
    BLAST

    Proteomic databases

    PRIDEiQ9ZW21.

    Expressioni

    Gene expression databases

    GenevestigatoriQ9ZW21.

    Interactioni

    Protein-protein interaction databases

    BioGridi2837. 6 interactions.
    DIPiDIP-48991N.
    IntActiQ9ZW21. 1 interaction.
    STRINGi3702.AT2G29380.1-P.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9ZW21.
    SMRiQ9ZW21. Positions 76-361.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini76 – 353278PP2C-likeAdd
    BLAST

    Sequence similaritiesi

    Belongs to the PP2C family.Curated
    Contains 1 PP2C-like domain.Curated

    Phylogenomic databases

    eggNOGiCOG0631.
    HOGENOMiHOG000233896.
    InParanoidiQ9ZW21.
    KOiK14497.
    OMAiRDEPACR.
    PhylomeDBiQ9ZW21.

    Family and domain databases

    Gene3Di3.60.40.10. 1 hit.
    InterProiIPR001932. PP2C-like_dom.
    IPR000222. PP2C_Mn2_Asp60_BS.
    IPR015655. Protein_Pase_2C.
    [Graphical view]
    PANTHERiPTHR13832. PTHR13832. 1 hit.
    PfamiPF00481. PP2C. 1 hit.
    [Graphical view]
    SMARTiSM00331. PP2C_SIG. 1 hit.
    SM00332. PP2Cc. 1 hit.
    [Graphical view]
    SUPFAMiSSF81606. SSF81606. 1 hit.
    PROSITEiPS01032. PP2C. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9ZW21-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAEICYEVVT DACPSSVYES TPAHSRRRPR FQTVMHEDWE KNCKRSKQEA    50
    LATRYSSIPR SSREDFSDQN VDVSSPRYGV SSVCGRRREM EDAVAIHPSF 100
    SSPKNSEFPQ HYFGVYDGHG CSHVAARCRE RLHKLVQEEL SSDMEDEEEW 150
    KTTMERSFTR MDKEVVSWGD SVVTANCKCD LQTPACDSVG STAVVSVITP 200
    DKIVVANCGD SRAVLCRNGK PVPLSTDHKP DRPDELDRIE GAGGRVIYWD 250
    CPRVLGVLAM SRAIGDNYLK PYVSCEPEVT ITDRRDDDCL ILASDGLWDV 300
    VSNETACSVA RMCLRGGGRR QDNEDPAISD KACTEASVLL TKLALARNSS 350
    DNVSVVVIDL RR 362
    Length:362
    Mass (Da):40,297
    Last modified:May 1, 1999 - v1
    Checksum:iD127B5057DA3E0D4
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC004561 Genomic DNA. Translation: AAC95200.1.
    CP002685 Genomic DNA. Translation: AEC08244.1.
    DQ056553 mRNA. Translation: AAY78704.1.
    BT022047 mRNA. Translation: AAY25459.1.
    BT023483 mRNA. Translation: AAY57322.1.
    PIRiF84695.
    RefSeqiNP_180499.1. NM_128492.2.
    UniGeneiAt.50109.

    Genome annotation databases

    EnsemblPlantsiAT2G29380.1; AT2G29380.1; AT2G29380.
    GeneIDi817487.
    KEGGiath:AT2G29380.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC004561 Genomic DNA. Translation: AAC95200.1 .
    CP002685 Genomic DNA. Translation: AEC08244.1 .
    DQ056553 mRNA. Translation: AAY78704.1 .
    BT022047 mRNA. Translation: AAY25459.1 .
    BT023483 mRNA. Translation: AAY57322.1 .
    PIRi F84695.
    RefSeqi NP_180499.1. NM_128492.2.
    UniGenei At.50109.

    3D structure databases

    ProteinModelPortali Q9ZW21.
    SMRi Q9ZW21. Positions 76-361.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 2837. 6 interactions.
    DIPi DIP-48991N.
    IntActi Q9ZW21. 1 interaction.
    STRINGi 3702.AT2G29380.1-P.

    Proteomic databases

    PRIDEi Q9ZW21.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi AT2G29380.1 ; AT2G29380.1 ; AT2G29380 .
    GeneIDi 817487.
    KEGGi ath:AT2G29380.

    Organism-specific databases

    TAIRi AT2G29380.

    Phylogenomic databases

    eggNOGi COG0631.
    HOGENOMi HOG000233896.
    InParanoidi Q9ZW21.
    KOi K14497.
    OMAi RDEPACR.
    PhylomeDBi Q9ZW21.

    Enzyme and pathway databases

    BioCyci ARA:AT2G29380-MONOMER.

    Gene expression databases

    Genevestigatori Q9ZW21.

    Family and domain databases

    Gene3Di 3.60.40.10. 1 hit.
    InterProi IPR001932. PP2C-like_dom.
    IPR000222. PP2C_Mn2_Asp60_BS.
    IPR015655. Protein_Pase_2C.
    [Graphical view ]
    PANTHERi PTHR13832. PTHR13832. 1 hit.
    Pfami PF00481. PP2C. 1 hit.
    [Graphical view ]
    SMARTi SM00331. PP2C_SIG. 1 hit.
    SM00332. PP2Cc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF81606. SSF81606. 1 hit.
    PROSITEi PS01032. PP2C. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Columbia.
    2. The Arabidopsis Information Resource (TAIR)
      Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: GENOME REANNOTATION.
      Strain: cv. Columbia.
    3. Underwood B.A., Xiao Y.-L., Moskal W.A. Jr., Monaghan E.L., Wang W., Redman J.C., Wu H.C., Utterback T., Town C.D.
      Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: cv. Columbia.
    4. "Arabidopsis ORF clones."
      Kim C.J., Chen H., Cheuk R.F., Shinn P., Ecker J.R.
      Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: cv. Columbia.
    5. "Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis."
      Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y.
      BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: GENE FAMILY, NOMENCLATURE.

    Entry informationi

    Entry nameiP2C24_ARATH
    AccessioniPrimary (citable) accession number: Q9ZW21
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 14, 2009
    Last sequence update: May 1, 1999
    Last modified: October 1, 2014
    This is version 98 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Arabidopsis thaliana
      Arabidopsis thaliana: entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3