Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q9ZVX1 (UBC23_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 95. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Web links·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable ubiquitin-conjugating enzyme E2 23

EC=6.3.2.19
Alternative name(s):
Ubiquitin carrier protein 23
Gene names
Name:UBC23
Ordered Locus Names:At2g16920
ORF Names:F12A24.10
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Protein attributes

Sequence length1102 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins By similarity.

Catalytic activity

ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine.

Pathway

Protein modification; protein ubiquitination.

Sequence similarities

Belongs to the ubiquitin-conjugating enzyme family.

Ontologies

Keywords
   Biological processUbl conjugation pathway
   LigandATP-binding
Nucleotide-binding
   Molecular functionLigase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentcytosol

Inferred from direct assay PubMed 21166475. Source: TAIR

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

ubiquitin-protein transferase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 11021102Probable ubiquitin-conjugating enzyme E2 23
PRO_0000345189

Regions

Compositional bias60 – 8627Asp-rich
Compositional bias262 – 2654Poly-Ser
Compositional bias658 – 6614Poly-Asp
Compositional bias747 – 7504Poly-Ser

Sites

Active site9361Glycyl thioester intermediate By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9ZVX1 [UniParc].

Last modified May 1, 1999. Version 1.
Checksum: DA2C11385355E8D9

FASTA1,102122,183
        10         20         30         40         50         60 
MEHEQDDPGT STNVGVDSSV DDSMASLSIC DSEHPNIYRQ DIVKNKKTGS VGVVSEVAGD 

        70         80         90        100        110        120 
SDSDSDISDE EEDDDDDEDN DDDDEDVEEG KKASEENVVN GDGEKKADGN YKCGALEGDQ 

       130        140        150        160        170        180 
IRVLWMDNTE PVQDINDVTV IDRGFLHGDY VASASEPTGQ VGVVVDVNIS VDLLAPDGSI 

       190        200        210        220        230        240 
HKDISTKNLK RVRDFAVGDY VVHGPWLGRI DDVLDNVTVL FDDGSMCKVL RVEPLRLKPI 

       250        260        270        280        290        300 
PKNNLEEDAN FPYYPGQRVK ASSSSVFKNS RWLSGLWKPN RLEGTVTKVT AGSIFVYWIA 

       310        320        330        340        350        360 
SAGFGPDSSV SPPEEQNPSN LTLLSCFTHA NWQVGDWCLL PSLNQSATIP LHKHVSKLRL 

       370        380        390        400        410        420 
YDSQADRQQK IGRDLEDVQD EVSGKVEPAG ITAEALPKVT SDDPPQRNPS VSKEPVHEPW 

       430        440        450        460        470        480 
PLHRKKIRKL VIRKDKKVKK KEESFEQALL VVNSRTRVDV SWQDGTIECR REAITLIPIE 

       490        500        510        520        530        540 
TPGDHEFVSE QYVVEKTSDD GDNTTEPRRA GVVKNVNAKD RTASVRWLNP LRRAEEPREF 

       550        560        570        580        590        600 
EKEEIVSVYE LEGHPDYDYC YGDVVVRLSP IAVALPASSP GNSFEEATQQ DNGYQDSESH 

       610        620        630        640        650        660 
QEAKILVDKE ENEPSTDLSK LSWVGNITGL KDGDIEVTWA DGTISTVGPH AVYVVGRDDD 

       670        680        690        700        710        720 
DESVAGESET SDAASWETLN DDDRGAPEIP EEDLGRSSSI EGNSDADIYA ENDSGRNGAL 

       730        740        750        760        770        780 
ALPLAAIEFV TRLASGIFSR ARKSVDSSSS DYTVENVYKQ AESTNPSDET DSLDDPSPSK 

       790        800        810        820        830        840 
VNVTDNCESK GTQANAKNIL SGETSTFLED EDKPVPSEGD SCSFRRFDIS QDPLDHHFLG 

       850        860        870        880        890        900 
VDGQKTKERQ WFKKVDQDWK ILQNNLPDGI FVRAYEDRMD LLRAVIVGAF GTPYQDGLFF 

       910        920        930        940        950        960 
FDFHLPSDYP SVPPSAYYHS GGWRLNPNLY EEGKVCLSLL NTWTGRGNEV WDPKSSSILQ 

       970        980        990       1000       1010       1020 
VLVSLQGLVL NSKPYFNEAG YDKQVGTAEG EKNSLGYNEN TFLLNCKTMM YLMRKPPKDF 

      1030       1040       1050       1060       1070       1080 
EELIKDHFRK RGYYILKACD AYMKGYLIGS LTKDASVIDE RSSANSTSVG FKLMLAKIAP 

      1090       1100 
KLFSALSEVG ADCNEFQHLQ QQ 

« Hide

References

« Hide 'large scale' references
[1]"Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana."
Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D., Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V., Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S., Cronin L.A. expand/collapse author list , Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J., Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M., Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O., Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.
Nature 402:761-768(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[2]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[3]"Phosphoproteomic analysis of nuclei-enriched fractions from Arabidopsis thaliana."
Jones A.M.E., MacLean D., Studholme D.J., Serna-Sanz A., Andreasson E., Rathjen J.P., Peck S.C.
J. Proteomics 72:439-451(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
Strain: cv. Columbia.
+Additional computationally mapped references.

Web resources

PlantsUBQ

A functional genomics database for the ubiquitin/26S proteasome proteolytic pathway in plants

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AC005167 Genomic DNA. Translation: AAC64223.1.
CP002685 Genomic DNA. Translation: AEC06554.1.
PIRH84545.
RefSeqNP_179284.1. NM_127245.2.
UniGeneAt.48482.

3D structure databases

ProteinModelPortalQ9ZVX1.
SMRQ9ZVX1. Positions 828-1091.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING3702.AT2G16920.1-P.

Proteomic databases

PaxDbQ9ZVX1.
PRIDEQ9ZVX1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT2G16920.1; AT2G16920.1; AT2G16920.
GeneID816195.
KEGGath:AT2G16920.

Organism-specific databases

TAIRAT2G16920.

Phylogenomic databases

eggNOGNOG238109.
HOGENOMHOG000237457.
InParanoidQ9ZVX1.
KOK10581.
OMAYELDGHP.
PhylomeDBQ9ZVX1.

Enzyme and pathway databases

BioCycARA:AT2G16920-MONOMER.
UniPathwayUPA00143.

Gene expression databases

GenevestigatorQ9ZVX1.

Family and domain databases

Gene3D3.10.110.10. 1 hit.
InterProIPR000608. UBQ-conjugat_E2.
IPR016135. UBQ-conjugating_enzyme/RWD.
[Graphical view]
PfamPF00179. UQ_con. 1 hit.
[Graphical view]
SUPFAMSSF54495. SSF54495. 1 hit.
PROSITEPS50127. UBIQUITIN_CONJUGAT_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

PROQ9ZVX1.

Entry information

Entry nameUBC23_ARATH
AccessionPrimary (citable) accession number: Q9ZVX1
Entry history
Integrated into UniProtKB/Swiss-Prot: July 22, 2008
Last sequence update: May 1, 1999
Last modified: May 14, 2014
This is version 95 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names