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Q9ZVQ4

- GSTZ2_ARATH

UniProt

Q9ZVQ4 - GSTZ2_ARATH

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Protein

Glutathione S-transferase Z2

Gene

GSTZ2

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

May be involved in the conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles and have a detoxification role against certain herbicides.By similarity

Catalytic activityi

RX + glutathione = HX + R-S-glutathione.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei49 – 491GlutathioneBy similarity
Binding sitei63 – 631Glutathione; via amide nitrogen and carbonyl oxygenBy similarity
Binding sitei115 – 1151GlutathioneBy similarity

GO - Molecular functioni

  1. glutathione transferase activity Source: UniProtKB-EC

GO - Biological processi

  1. aromatic amino acid family metabolic process Source: InterPro
  2. response to toxic substance Source: UniProtKB-KW
  3. toxin catabolic process Source: TAIR
Complete GO annotation...

Keywords - Molecular functioni

Transferase

Keywords - Biological processi

Detoxification

Enzyme and pathway databases

BioCyciARA:AT2G02380-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutathione S-transferase Z2 (EC:2.5.1.18)
Short name:
AtGSTZ2
Alternative name(s):
GST class-zeta member 2
Gene namesi
Name:GSTZ2
Ordered Locus Names:At2g02380
ORF Names:T16F16.17
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
ProteomesiUP000006548: Chromosome 2

Organism-specific databases

TAIRiAT2G02380.

Subcellular locationi

Cytoplasmcytosol By similarity

GO - Cellular componenti

  1. cytoplasm Source: TAIR
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 223223Glutathione S-transferase Z2PRO_0000186030Add
BLAST

Proteomic databases

PRIDEiQ9ZVQ4.

Expressioni

Gene expression databases

GenevestigatoriQ9ZVQ4.

Interactioni

Protein-protein interaction databases

STRINGi3702.AT2G02380.1-P.

Structurei

3D structure databases

ProteinModelPortaliQ9ZVQ4.
SMRiQ9ZVQ4. Positions 11-222.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini10 – 9182GST N-terminalAdd
BLAST
Domaini96 – 221126GST C-terminalAdd
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni20 – 256Glutathione bindingBy similarity
Regioni20 – 212Glutathione bindingBy similarity
Regioni49 – 502Glutathione bindingBy similarity
Regioni62 – 632Glutathione bindingBy similarity
Regioni75 – 762Glutathione bindingBy similarity
Regioni119 – 1213Glutathione bindingBy similarity

Sequence similaritiesi

Belongs to the GST superfamily. Zeta family.Curated
Contains 1 GST C-terminal domain.Curated
Contains 1 GST N-terminal domain.Curated

Phylogenomic databases

eggNOGiCOG0625.
HOGENOMiHOG000125758.
InParanoidiQ9ZVQ4.
KOiK01800.
OMAiRVRTFLM.
PhylomeDBiQ9ZVQ4.

Family and domain databases

Gene3Di1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProiIPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR004046. GST_C.
IPR005955. Mal_ac_isom.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamiPF00043. GST_C. 1 hit.
PF13417. GST_N_3. 1 hit.
[Graphical view]
SUPFAMiSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
TIGRFAMsiTIGR01262. maiA. 1 hit.
PROSITEiPS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9ZVQ4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSYVTDFYQA KLKLYSYWRS SCAHRVRIAL TLKGLDYEYI PVNLLKGDQS
60 70 80 90 100
DSDFKKINPM GTVPALVDGD VVINDSFAII MYLDDKYPEP PLLPSDYHKR
110 120 130 140 150
AVNYQATSIV MSGIQPHQNM ALFRYLEDKI NAEEKTAWIT NAITKGFTAL
160 170 180 190 200
EKLLVSCAGK YATGDEVYLA DLFLAPQIHA AFNRFHINME PFPTLARFYE
210 220
SYNELPAFQN AVPEKQPDTP STI
Length:223
Mass (Da):25,352
Last modified:May 1, 1999 - v1
Checksum:iAAE7E85746610512
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC005312 Genomic DNA. Translation: AAC78520.1.
CP002685 Genomic DNA. Translation: AEC05572.1.
PIRiA84436.
RefSeqiNP_178343.1. NM_126295.1.
UniGeneiAt.70421.

Genome annotation databases

EnsemblPlantsiAT2G02380.1; AT2G02380.1; AT2G02380.
GeneIDi814769.
KEGGiath:AT2G02380.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC005312 Genomic DNA. Translation: AAC78520.1 .
CP002685 Genomic DNA. Translation: AEC05572.1 .
PIRi A84436.
RefSeqi NP_178343.1. NM_126295.1.
UniGenei At.70421.

3D structure databases

ProteinModelPortali Q9ZVQ4.
SMRi Q9ZVQ4. Positions 11-222.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 3702.AT2G02380.1-P.

Proteomic databases

PRIDEi Q9ZVQ4.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi AT2G02380.1 ; AT2G02380.1 ; AT2G02380 .
GeneIDi 814769.
KEGGi ath:AT2G02380.

Organism-specific databases

TAIRi AT2G02380.

Phylogenomic databases

eggNOGi COG0625.
HOGENOMi HOG000125758.
InParanoidi Q9ZVQ4.
KOi K01800.
OMAi RVRTFLM.
PhylomeDBi Q9ZVQ4.

Enzyme and pathway databases

BioCyci ARA:AT2G02380-MONOMER.

Miscellaneous databases

PROi Q9ZVQ4.

Gene expression databases

Genevestigatori Q9ZVQ4.

Family and domain databases

Gene3Di 1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProi IPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR004046. GST_C.
IPR005955. Mal_ac_isom.
IPR012336. Thioredoxin-like_fold.
[Graphical view ]
Pfami PF00043. GST_C. 1 hit.
PF13417. GST_N_3. 1 hit.
[Graphical view ]
SUPFAMi SSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
TIGRFAMsi TIGR01262. maiA. 1 hit.
PROSITEi PS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  2. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  3. "Probing the diversity of the Arabidopsis glutathione S-transferase gene family."
    Wagner U., Edwards R., Dixon D.P., Mauch F.
    Plant Mol. Biol. 49:515-532(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY, NOMENCLATURE.

Entry informationi

Entry nameiGSTZ2_ARATH
AccessioniPrimary (citable) accession number: Q9ZVQ4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: May 1, 1999
Last modified: October 29, 2014
This is version 115 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3