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Q9ZVQ4

- GSTZ2_ARATH

UniProt

Q9ZVQ4 - GSTZ2_ARATH

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Protein

Glutathione S-transferase Z2

Gene
GSTZ2, At2g02380, T16F16.17
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

May be involved in the conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles and have a detoxification role against certain herbicides By similarity.

Catalytic activityi

RX + glutathione = HX + R-S-glutathione.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei49 – 491Glutathione By similarity
Binding sitei63 – 631Glutathione; via amide nitrogen and carbonyl oxygen By similarity
Binding sitei115 – 1151Glutathione By similarity

GO - Molecular functioni

  1. glutathione transferase activity Source: UniProtKB-EC

GO - Biological processi

  1. aromatic amino acid family metabolic process Source: InterPro
  2. response to toxic substance Source: UniProtKB-KW
  3. toxin catabolic process Source: TAIR
Complete GO annotation...

Keywords - Molecular functioni

Transferase

Keywords - Biological processi

Detoxification

Enzyme and pathway databases

BioCyciARA:AT2G02380-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutathione S-transferase Z2 (EC:2.5.1.18)
Short name:
AtGSTZ2
Alternative name(s):
GST class-zeta member 2
Gene namesi
Name:GSTZ2
Ordered Locus Names:At2g02380
ORF Names:T16F16.17
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
ProteomesiUP000006548: Chromosome 2

Organism-specific databases

TAIRiAT2G02380.

Subcellular locationi

Cytoplasmcytosol By similarity

GO - Cellular componenti

  1. cytoplasm Source: TAIR
  2. cytosol Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 223223Glutathione S-transferase Z2PRO_0000186030Add
BLAST

Proteomic databases

PRIDEiQ9ZVQ4.

Expressioni

Gene expression databases

GenevestigatoriQ9ZVQ4.

Interactioni

Protein-protein interaction databases

STRINGi3702.AT2G02380.1-P.

Structurei

3D structure databases

ProteinModelPortaliQ9ZVQ4.
SMRiQ9ZVQ4. Positions 11-222.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini10 – 9182GST N-terminalAdd
BLAST
Domaini96 – 221126GST C-terminalAdd
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni20 – 256Glutathione binding By similarity
Regioni20 – 212Glutathione binding By similarity
Regioni49 – 502Glutathione binding By similarity
Regioni62 – 632Glutathione binding By similarity
Regioni75 – 762Glutathione binding By similarity
Regioni119 – 1213Glutathione binding By similarity

Sequence similaritiesi

Belongs to the GST superfamily. Zeta family.

Phylogenomic databases

eggNOGiCOG0625.
HOGENOMiHOG000125758.
InParanoidiQ9ZVQ4.
KOiK01800.
OMAiRVRTFLM.
PhylomeDBiQ9ZVQ4.

Family and domain databases

Gene3Di1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProiIPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR004046. GST_C.
IPR005955. Mal_ac_isom.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamiPF00043. GST_C. 1 hit.
PF13417. GST_N_3. 1 hit.
[Graphical view]
SUPFAMiSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
TIGRFAMsiTIGR01262. maiA. 1 hit.
PROSITEiPS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9ZVQ4-1 [UniParc]FASTAAdd to Basket

« Hide

MSYVTDFYQA KLKLYSYWRS SCAHRVRIAL TLKGLDYEYI PVNLLKGDQS    50
DSDFKKINPM GTVPALVDGD VVINDSFAII MYLDDKYPEP PLLPSDYHKR 100
AVNYQATSIV MSGIQPHQNM ALFRYLEDKI NAEEKTAWIT NAITKGFTAL 150
EKLLVSCAGK YATGDEVYLA DLFLAPQIHA AFNRFHINME PFPTLARFYE 200
SYNELPAFQN AVPEKQPDTP STI 223
Length:223
Mass (Da):25,352
Last modified:May 1, 1999 - v1
Checksum:iAAE7E85746610512
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC005312 Genomic DNA. Translation: AAC78520.1.
CP002685 Genomic DNA. Translation: AEC05572.1.
PIRiA84436.
RefSeqiNP_178343.1. NM_126295.1.
UniGeneiAt.70421.

Genome annotation databases

EnsemblPlantsiAT2G02380.1; AT2G02380.1; AT2G02380.
GeneIDi814769.
KEGGiath:AT2G02380.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC005312 Genomic DNA. Translation: AAC78520.1 .
CP002685 Genomic DNA. Translation: AEC05572.1 .
PIRi A84436.
RefSeqi NP_178343.1. NM_126295.1.
UniGenei At.70421.

3D structure databases

ProteinModelPortali Q9ZVQ4.
SMRi Q9ZVQ4. Positions 11-222.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 3702.AT2G02380.1-P.

Proteomic databases

PRIDEi Q9ZVQ4.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi AT2G02380.1 ; AT2G02380.1 ; AT2G02380 .
GeneIDi 814769.
KEGGi ath:AT2G02380.

Organism-specific databases

TAIRi AT2G02380.

Phylogenomic databases

eggNOGi COG0625.
HOGENOMi HOG000125758.
InParanoidi Q9ZVQ4.
KOi K01800.
OMAi RVRTFLM.
PhylomeDBi Q9ZVQ4.

Enzyme and pathway databases

BioCyci ARA:AT2G02380-MONOMER.

Miscellaneous databases

PROi Q9ZVQ4.

Gene expression databases

Genevestigatori Q9ZVQ4.

Family and domain databases

Gene3Di 1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProi IPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR004046. GST_C.
IPR005955. Mal_ac_isom.
IPR012336. Thioredoxin-like_fold.
[Graphical view ]
Pfami PF00043. GST_C. 1 hit.
PF13417. GST_N_3. 1 hit.
[Graphical view ]
SUPFAMi SSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
TIGRFAMsi TIGR01262. maiA. 1 hit.
PROSITEi PS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  2. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  3. "Probing the diversity of the Arabidopsis glutathione S-transferase gene family."
    Wagner U., Edwards R., Dixon D.P., Mauch F.
    Plant Mol. Biol. 49:515-532(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY, NOMENCLATURE.

Entry informationi

Entry nameiGSTZ2_ARATH
AccessioniPrimary (citable) accession number: Q9ZVQ4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: May 1, 1999
Last modified: May 14, 2014
This is version 113 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi