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Protein

Probable tyrosine-protein phosphatase At1g05000

Gene

At1g05000

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.PROSITE-ProRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei150Phosphocysteine intermediatePROSITE-ProRule annotation1

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Names & Taxonomyi

Protein namesi
Recommended name:
Probable tyrosine-protein phosphatase At1g05000 (EC:3.1.3.48)
Gene namesi
Ordered Locus Names:At1g05000
ORF Names:T7A14.14
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

TAIRiAT1G05000.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000949231 – 215Probable tyrosine-protein phosphatase At1g05000Add BLAST215

Expressioni

Gene expression databases

ExpressionAtlasiQ9ZVN4. baseline and differential.
GenevisibleiQ9ZVN4. AT.

Interactioni

Subunit structurei

Homomultimer.Curated

Protein-protein interaction databases

BioGridi24583. 17 interactors.

Structurei

Secondary structure

1215
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi60 – 63Combined sources4
Beta strandi66 – 70Combined sources5
Helixi74 – 83Combined sources10
Beta strandi86 – 90Combined sources5
Helixi98 – 107Combined sources10
Beta strandi110 – 113Combined sources4
Helixi121 – 123Combined sources3
Helixi128 – 139Combined sources12
Helixi141 – 143Combined sources3
Beta strandi145 – 149Combined sources5
Beta strandi151 – 155Combined sources5
Helixi156 – 167Combined sources12
Helixi172 – 183Combined sources12
Helixi184 – 186Combined sources3
Helixi189 – 196Combined sources8

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1XRIX-ray3.30A/B52-202[»]
2Q47X-ray3.30A/B52-202[»]
ProteinModelPortaliQ9ZVN4.
SMRiQ9ZVN4.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ9ZVN4.

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi7 – 10Poly-Thr4

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000188365.
InParanoidiQ9ZVN4.
KOiK18045.
PhylomeDBiQ9ZVN4.

Family and domain databases

Gene3Di3.90.190.10. 1 hit.
InterProiIPR029021. Prot-tyrosine_phosphatase-like.
IPR016130. Tyr_Pase_AS.
IPR020428. Tyr_Pase_SIW14-lik_euk.
IPR004861. Tyr_Pase_SIW14-like.
[Graphical view]
PfamiPF03162. Y_phosphatase2. 1 hit.
[Graphical view]
PRINTSiPR01911. PFDSPHPHTASE.
SUPFAMiSSF52799. SSF52799. 1 hit.
PROSITEiPS00383. TYR_PHOSPHATASE_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

This entry describes 1 isoform i produced by alternative splicing. AlignAdd to basket

Note: A number of isoforms are produced. According to EST sequences.
Isoform 1 (identifier: Q9ZVN4-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MKLVEKTTTT EQDNGEDFCR TIIEVSEVNR NVFQAPGGEA DPFRVVSGEE
60 70 80 90 100
LHLIPPLNFS MVDNGIFRSG FPDSANFSFL QTLGLRSIIY LCPEPYPESN
110 120 130 140 150
LQFLKSNGIR LFQFGIEGNK EPFVNIPDHK IRMALKVLLD EKNHPVLIHC
160 170 180 190 200
KRGKHRTGCL VGCLRKLQKW CLTSIFDEYQ RFAAAKARVS DQRFMEIFDV
210
SSFSHIPMSF SCSIR
Length:215
Mass (Da):24,537
Last modified:May 1, 1999 - v1
Checksum:i24BCB3033CBCFA3A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC005322 Genomic DNA. Translation: AAC97999.1.
CP002684 Genomic DNA. Translation: AEE27777.1.
BT005210 mRNA. Translation: AAO63274.1.
PIRiG86183.
RefSeqiNP_171993.1. NM_100379.3. [Q9ZVN4-1]
UniGeneiAt.43231.

Genome annotation databases

EnsemblPlantsiAT1G05000.1; AT1G05000.1; AT1G05000. [Q9ZVN4-1]
GeneIDi839348.
GrameneiAT1G05000.1; AT1G05000.1; AT1G05000.
KEGGiath:AT1G05000.

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC005322 Genomic DNA. Translation: AAC97999.1.
CP002684 Genomic DNA. Translation: AEE27777.1.
BT005210 mRNA. Translation: AAO63274.1.
PIRiG86183.
RefSeqiNP_171993.1. NM_100379.3. [Q9ZVN4-1]
UniGeneiAt.43231.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1XRIX-ray3.30A/B52-202[»]
2Q47X-ray3.30A/B52-202[»]
ProteinModelPortaliQ9ZVN4.
SMRiQ9ZVN4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi24583. 17 interactors.

Protocols and materials databases

DNASUi839348.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT1G05000.1; AT1G05000.1; AT1G05000. [Q9ZVN4-1]
GeneIDi839348.
GrameneiAT1G05000.1; AT1G05000.1; AT1G05000.
KEGGiath:AT1G05000.

Organism-specific databases

TAIRiAT1G05000.

Phylogenomic databases

HOGENOMiHOG000188365.
InParanoidiQ9ZVN4.
KOiK18045.
PhylomeDBiQ9ZVN4.

Miscellaneous databases

EvolutionaryTraceiQ9ZVN4.
PROiQ9ZVN4.

Gene expression databases

ExpressionAtlasiQ9ZVN4. baseline and differential.
GenevisibleiQ9ZVN4. AT.

Family and domain databases

Gene3Di3.90.190.10. 1 hit.
InterProiIPR029021. Prot-tyrosine_phosphatase-like.
IPR016130. Tyr_Pase_AS.
IPR020428. Tyr_Pase_SIW14-lik_euk.
IPR004861. Tyr_Pase_SIW14-like.
[Graphical view]
PfamiPF03162. Y_phosphatase2. 1 hit.
[Graphical view]
PRINTSiPR01911. PFDSPHPHTASE.
SUPFAMiSSF52799. SSF52799. 1 hit.
PROSITEiPS00383. TYR_PHOSPHATASE_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiY1500_ARATH
AccessioniPrimary (citable) accession number: Q9ZVN4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 30, 2005
Last sequence update: May 1, 1999
Last modified: November 30, 2016
This is version 98 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.