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Q9ZV40 (XTH21_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 98. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable xyloglucan endotransglucosylase/hydrolase protein 21
Short name=At-XTH21
Short name=XTH-21
EC=2.4.1.207
Gene names
Name:XTH21
Synonyms:XTR17
Ordered Locus Names:At2g18800
ORF Names:MSF3.18
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis

Protein attributes

Sequence length305 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Catalyzes xyloglucan endohydrolysis (XEH) and/or endotransglycosylation (XET). Cleaves and religates xyloglucan polymers, an essential constituent of the primary cell wall, and thereby participates in cell wall construction of growing tissues By similarity.

Catalytic activity

Breaks a beta-(1->4) bond in the backbone of a xyloglucan and transfers the xyloglucanyl segment on to O-4 of the non-reducing terminal glucose residue of an acceptor, which can be a xyloglucan or an oligosaccharide of xyloglucan.

Subcellular location

Secreted › cell wall Probable. Secreted › extracellular space › apoplast Probable.

Tissue specificity

Predominantly expressed in green siliques. Ref.3

Induction

Down-regulated by auxin. Ref.3

Post-translational modification

Contains at least one intrachain disulfide bond essential for its enzymatic activity By similarity.

Sequence similarities

Belongs to the glycosyl hydrolase 16 family. XTH group 2 subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2525 Potential
Chain26 – 305280Probable xyloglucan endotransglucosylase/hydrolase protein 21
PRO_0000011821

Sites

Active site1021Nucleophile By similarity
Active site1061Proton donor By similarity

Amino acid modifications

Glycosylation461N-linked (GlcNAc...) Potential
Glycosylation1101N-linked (GlcNAc...) Potential
Glycosylation1461N-linked (GlcNAc...) Potential
Glycosylation2061N-linked (GlcNAc...) Potential
Glycosylation2311N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
Q9ZV40 [UniParc].

Last modified May 1, 1999. Version 1.
Checksum: 9B4BD59F25FA6DC7

FASTA30534,145
        10         20         30         40         50         60 
MVSSTLLVMS ISLFLGLSIL LVVHGKDFNQ DIDITWGDGR GNILNNGTLL NLGLDQSSGS 

        70         80         90        100        110        120 
GFQSKAEYLY GKVDMQIKLV PGNSAGTVTT FYLKSQGLTW DEIDFEFLGN VSGDPYIVHT 

       130        140        150        160        170        180 
NVYTQGKGDR EQQFYLWFDP TAAFHNYSIL WNPSHIVFYI DGKPIREFKN LEVLGVAYPK 

       190        200        210        220        230        240 
NQPMRMYGSL WNADDWATRG GLVKTNWSQG PFVASFMNYN SENACVWSIV NGTTTTSPCS 

       250        260        270        280        290        300 
PGDSTSSSSS STSEWFSQRG MDSSSKKVLR WVQRKFMVYN YCKDKKRFSN GLPVECTAKN 


KNTKS

« Hide

References

« Hide 'large scale' references
[1]"Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana."
Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D., Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V., Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S., Cronin L.A. expand/collapse author list , Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J., Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M., Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O., Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.
Nature 402:761-768(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[2]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[3]"A comprehensive expression analysis of all members of a gene family encoding cell-wall enzymes allowed us to predict cis-regulatory regions involved in cell-wall construction in specific organs of Arabidopsis."
Yokoyama R., Nishitani K.
Plant Cell Physiol. 42:1025-1033(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: TISSUE SPECIFICITY, INDUCTION.
[4]"The XTH family of enzymes involved in xyloglucan endotransglucosylation and endohydrolysis: current perspectives and a new unifying nomenclature."
Rose J.K.C., Braam J., Fry S.C., Nishitani K.
Plant Cell Physiol. 43:1421-1435(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NOMENCLATURE.
+Additional computationally mapped references.

Web resources

XTH-World

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AC005724 Genomic DNA. Translation: AAD08949.1.
CP002685 Genomic DNA. Translation: AEC06809.1.
IPIIPI00536986.
PIRG84568.
RefSeqNP_179470.1. NM_127436.1.
UniGeneAt.39941.

3D structure databases

ProteinModelPortalQ9ZV40.
SMRQ9ZV40. Positions 28-296.
ModBaseSearch...

Protein-protein interaction databases

STRING3702.AT2G18800.1-P.

Protein family/group databases

CAZyGH16. Glycoside Hydrolase Family 16.

Proteomic databases

PaxDbQ9ZV40.
PRIDEQ9ZV40.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT2G18800.1; AT2G18800.1; AT2G18800.
GeneID816395.
KEGGath:AT2G18800.

Organism-specific databases

TAIRAt2g18800.

Phylogenomic databases

eggNOGCOG2273.
HOGENOMHOG000236368.
InParanoidQ9ZV40.
KOK08235.
OMALWNPSHI.
PhylomeDBQ9ZV40.
ProtClustDBCLSN2912889.

Gene expression databases

GenevestigatorQ9ZV40.
GermOnlineAT2G18800. Arabidopsis thaliana.

Family and domain databases

Gene3D2.60.120.200. 1 hit.
InterProIPR008985. ConA-like_lec_gl_sf.
IPR013320. ConA-like_subgrp.
IPR000757. Glyco_hydro_16.
IPR008263. Glycoside_hydrolase_16_AS.
IPR016455. XET.
IPR010713. XET_C.
[Graphical view]
PfamPF00722. Glyco_hydro_16. 1 hit.
PF06955. XET_C. 1 hit.
[Graphical view]
PIRSFPIRSF005604. XET. 1 hit.
SUPFAMSSF49899. ConA_like_lec_gl. 1 hit.
PROSITEPS01034. GLYCOSYL_HYDROL_F16. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameXTH21_ARATH
AccessionPrimary (citable) accession number: Q9ZV40
Entry history
Integrated into UniProtKB/Swiss-Prot: November 28, 2003
Last sequence update: May 1, 1999
Last modified: May 1, 2013
This is version 98 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names

SIMILARITY comments

Index of protein domains and families

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