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Protein

Vesicle-associated membrane protein 721

Gene

VAMP721

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Involved in the targeting and/or fusion of transport vesicles to their target membrane.1 Publication

GO - Molecular functioni

GO - Biological processi

  • cell plate formation involved in plant-type cell wall biogenesis Source: TAIR
  • exocytosis Source: GO_Central
  • protein targeting to plasma membrane Source: TAIR
  • vesicle fusion Source: GO_Central
Complete GO annotation...

Keywords - Biological processi

Protein transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Vesicle-associated membrane protein 7211 Publication
Short name:
AtVAMP7211 Publication
Alternative name(s):
v-SNARE synaptobrevin 7B1 Publication
Short name:
AtVAMP7B1 Publication
Gene namesi
Name:VAMP7211 Publication
Synonyms:VAMP7B1 Publication
Ordered Locus Names:At1g04750Imported
ORF Names:F13M7.26Imported, F13M7_23, T1G11.1Imported
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

TAIRiAT1G04750.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 196196CytoplasmicSequence analysisAdd
BLAST
Transmembranei197 – 21721Helical; Anchor for type IV membrane proteinSequence analysisAdd
BLAST
Topological domaini218 – 2192VesicularSequence analysis

GO - Cellular componenti

  • cell plate Source: TAIR
  • early endosome membrane Source: UniProtKB-SubCell
  • endosome Source: TAIR
  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: TAIR
  • plasmodesma Source: TAIR
  • SNARE complex Source: GO_Central
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Endosome, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 219219Vesicle-associated membrane protein 721PRO_0000206754Add
BLAST

Post-translational modificationi

Ubiquitinated.1 Publication

Keywords - PTMi

Ubl conjugation

Proteomic databases

PaxDbiQ9ZTW3.
PRIDEiQ9ZTW3.

PTM databases

iPTMnetiQ9ZTW3.

Expressioni

Tissue specificityi

Expressed in flowers, leaves, stems and roots.1 Publication

Gene expression databases

ExpressionAtlasiQ9ZTW3. baseline and differential.
GenevisibleiQ9ZTW3. AT.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

BioGridi24654. 15 interactions.
IntActiQ9ZTW3. 7 interactions.
STRINGi3702.AT1G04750.1.

Structurei

3D structure databases

ProteinModelPortaliQ9ZTW3.
SMRiQ9ZTW3. Positions 5-188.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini10 – 114105LonginPROSITE-ProRule annotationAdd
BLAST
Domaini130 – 19061v-SNARE coiled-coil homologyPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the synaptobrevin family.Curated
Contains 1 longin domain.PROSITE-ProRule annotation
Contains 1 v-SNARE coiled-coil homology domain.PROSITE-ProRule annotation

Keywords - Domaini

Coiled coil, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0859. Eukaryota.
COG5143. LUCA.
HOGENOMiHOG000042712.
InParanoidiQ9ZTW3.
OMAiPMACLER.
PhylomeDBiQ9ZTW3.

Family and domain databases

Gene3Di1.10.3840.10. 1 hit.
3.30.450.50. 1 hit.
InterProiIPR011012. Longin-like_dom.
IPR010908. Longin_dom.
IPR001388. Synaptobrevin.
[Graphical view]
PfamiPF13774. Longin. 1 hit.
PF00957. Synaptobrevin. 1 hit.
[Graphical view]
PRINTSiPR00219. SYNAPTOBREVN.
SMARTiSM01270. Longin. 1 hit.
[Graphical view]
SUPFAMiSSF64356. SSF64356. 1 hit.
PROSITEiPS50859. LONGIN. 1 hit.
PS00417. SYNAPTOBREVIN. 1 hit.
PS50892. V_SNARE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

This entry describes 1 isoform i produced by alternative splicing. AlignAdd to basket

Note: A number of isoforms are produced. According to EST sequences.

Isoform 1 (identifier: Q9ZTW3-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MAQQSLIYSF VARGTVILVE FTDFKGNFTS IAAQCLQKLP SSNNKFTYNC
60 70 80 90 100
DGHTFNYLVE DGFTYCVVAV DSAGRQIPMS FLERVKEDFN KRYGGGKAAT
110 120 130 140 150
AQANSLNKEF GSKLKEHMQY CMDHPDEISK LAKVKAQVSE VKGVMMENIE
160 170 180 190 200
KVLDRGEKIE LLVDKTENLR SQAQDFRTTG TQMRRKMWLQ NMKIKLIVLA
210
IIIALILIIV LSVCHGFKC
Length:219
Mass (Da):24,765
Last modified:May 1, 1999 - v1
Checksum:i7F234F6DB5138082
GO

Sequence cautioni

The sequence AAB80624.1 differs from that shown. Reason: Erroneous gene model prediction. Curated
The sequence AAF40468.1 differs from that shown. Reason: Erroneous gene model prediction. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF025333 mRNA. Translation: AAC98905.1.
AC002376 Genomic DNA. Translation: AAB80624.1. Sequence problems.
AC004809 Genomic DNA. Translation: AAF40468.1. Sequence problems.
CP002684 Genomic DNA. Translation: AEE27738.1.
AY079164 mRNA. Translation: AAL85003.1.
AY133661 mRNA. Translation: AAM91491.1.
PIRiD86180.
E86180.
RefSeqiNP_171967.1. NM_100353.3. [Q9ZTW3-1]
UniGeneiAt.20250.
At.67689.

Genome annotation databases

EnsemblPlantsiAT1G04750.1; AT1G04750.1; AT1G04750. [Q9ZTW3-1]
GeneIDi839419.
KEGGiath:AT1G04750.

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF025333 mRNA. Translation: AAC98905.1.
AC002376 Genomic DNA. Translation: AAB80624.1. Sequence problems.
AC004809 Genomic DNA. Translation: AAF40468.1. Sequence problems.
CP002684 Genomic DNA. Translation: AEE27738.1.
AY079164 mRNA. Translation: AAL85003.1.
AY133661 mRNA. Translation: AAM91491.1.
PIRiD86180.
E86180.
RefSeqiNP_171967.1. NM_100353.3. [Q9ZTW3-1]
UniGeneiAt.20250.
At.67689.

3D structure databases

ProteinModelPortaliQ9ZTW3.
SMRiQ9ZTW3. Positions 5-188.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi24654. 15 interactions.
IntActiQ9ZTW3. 7 interactions.
STRINGi3702.AT1G04750.1.

PTM databases

iPTMnetiQ9ZTW3.

Proteomic databases

PaxDbiQ9ZTW3.
PRIDEiQ9ZTW3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT1G04750.1; AT1G04750.1; AT1G04750. [Q9ZTW3-1]
GeneIDi839419.
KEGGiath:AT1G04750.

Organism-specific databases

TAIRiAT1G04750.

Phylogenomic databases

eggNOGiKOG0859. Eukaryota.
COG5143. LUCA.
HOGENOMiHOG000042712.
InParanoidiQ9ZTW3.
OMAiPMACLER.
PhylomeDBiQ9ZTW3.

Miscellaneous databases

PROiQ9ZTW3.

Gene expression databases

ExpressionAtlasiQ9ZTW3. baseline and differential.
GenevisibleiQ9ZTW3. AT.

Family and domain databases

Gene3Di1.10.3840.10. 1 hit.
3.30.450.50. 1 hit.
InterProiIPR011012. Longin-like_dom.
IPR010908. Longin_dom.
IPR001388. Synaptobrevin.
[Graphical view]
PfamiPF13774. Longin. 1 hit.
PF00957. Synaptobrevin. 1 hit.
[Graphical view]
PRINTSiPR00219. SYNAPTOBREVN.
SMARTiSM01270. Longin. 1 hit.
[Graphical view]
SUPFAMiSSF64356. SSF64356. 1 hit.
PROSITEiPS50859. LONGIN. 1 hit.
PS00417. SYNAPTOBREVIN. 1 hit.
PS50892. V_SNARE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Nikoloff D.M., Somerville C.R.
    Submitted (SEP-1997) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Tissue: Flower, Rosette leaf, Seedling, Silique and Stem.
  2. "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana."
    Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K.
    , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.
    Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  3. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  4. "Empirical analysis of transcriptional activity in the Arabidopsis genome."
    Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.
    , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
    Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Columbia.
  5. "The Arabidopsis genome. An abundance of soluble N-ethylmaleimide-sensitive factor adaptor protein receptors."
    Sanderfoot A.A., Assaad F.F., Raikhel N.V.
    Plant Physiol. 124:1558-1569(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY, NOMENCLATURE.
  6. "Systematic analysis of SNARE molecules in Arabidopsis: dissection of the post-Golgi network in plant cells."
    Uemura T., Ueda T., Ohniwa R.L., Nakano A., Takeyasu K., Sato M.H.
    Cell Struct. Funct. 29:49-65(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: TISSUE SPECIFICITY, SUBCELLULAR LOCATION.
  7. "Tandem affinity purification and mass spectrometric analysis of ubiquitylated proteins in Arabidopsis."
    Saracco S.A., Hansson M., Scalf M., Walker J.M., Smith L.M., Vierstra R.D.
    Plant J. 59:344-358(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: UBIQUITINATION [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiVA721_ARATH
AccessioniPrimary (citable) accession number: Q9ZTW3
Secondary accession number(s): O23011, Q9MAS4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 17, 2003
Last sequence update: May 1, 1999
Last modified: June 8, 2016
This is version 123 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.