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Q9ZTU2

- Q9ZTU2_LOLPR

UniProt

Q9ZTU2 - Q9ZTU2_LOLPR

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Protein
Submitted name:

Caffeic acid O-methyltransferase

Gene

OMT1

Organism
Lolium perenne (Perennial ryegrass)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei160 – 1601S-adenosyl-L-homocysteine 1Imported
Binding sitei181 – 1811S-adenosyl-L-homocysteine 1Imported
Binding sitei205 – 2051S-adenosyl-L-homocysteine 1; via carbonyl oxygenImported
Binding sitei228 – 2281S-adenosyl-L-homocysteine 1Imported
Binding sitei228 – 2281S-adenosyl-L-homocysteine 2
Binding sitei262 – 2621S-adenosyl-L-homocysteine 1Imported
Binding sitei262 – 2621S-adenosyl-L-homocysteine 2
Active sitei266 – 2661Proton acceptorUniRule annotation

GO - Molecular functioni

  1. catechol O-methyltransferase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

MethyltransferaseSAAS annotationImported, Transferase

Keywords - Ligandi

S-adenosyl-L-methionineSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Caffeic acid O-methyltransferaseImported (EC:2.1.1.6Imported)
Gene namesi
Name:OMT1Imported
OrganismiLolium perenne (Perennial ryegrass)Imported
Taxonomic identifieri4522 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladePooideaePoeaeLoliinaeLolium

Organism-specific databases

GrameneiQ9ZTU2.

Structurei

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3P9CX-ray1.80A1-360[»]
3P9IX-ray1.85A/B/C/D1-360[»]
3P9KX-ray2.25A/B/C/D1-360[»]
ProteinModelPortaliQ9ZTU2.
SMRiQ9ZTU2. Positions 2-360.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ9ZTU2.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni205 – 2062S-adenosyl-L-homocysteine 2 binding
Regioni248 – 2492S-adenosyl-L-homocysteine 1 bindingImported
Regioni248 – 2492S-adenosyl-L-homocysteine 2 binding

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
3.40.50.150. 1 hit.
InterProiIPR016461. COMT.
IPR001077. O_MeTrfase_2.
IPR012967. Plant_MeTrfase_dimerisation.
IPR029063. SAM-dependent_MTases-like.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF08100. Dimerisation. 1 hit.
PF00891. Methyltransf_2. 1 hit.
[Graphical view]
PIRSFiPIRSF005739. O-mtase. 1 hit.
SUPFAMiSSF53335. SSF53335. 1 hit.
PROSITEiPS51588. SAM_MT_COMT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9ZTU2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MGSTAADMAA SADEDACMFA LQLASSSVLP MTLKNAIELG LLEILVAAGG
60 70 80 90 100
KSLTPTEVAA KLPSAANPEA PDMVDRILRL LASYNVVTCL VEEGKDGRLS
110 120 130 140 150
RSYGAAPVCK FLTPNEDGVS MAALALMNQD KVLMESWYYL KDAVLDGGIP
160 170 180 190 200
FNKAYGMSAF EYHGTDPRFN RVFNEGMKNH SIIITKKLLE LYHGFEGLGT
210 220 230 240 250
LVDVGGGVGA TVAAIAAHYP TIKGVNFDLP HVISEAPQFP GVTHVGGDMF
260 270 280 290 300
KEVPSGDTIL MKWILHDWSD QHCATLLKNC YDALPAHGKV VLVQCILPVN
310 320 330 340 350
PEANPSSQGV FHVDMIMLAH NPGGRERYER EFQALARGAG FTGVKSTYIY
360
ANAWAIEFTK
Length:360
Mass (Da):38,769
Last modified:May 1, 1999 - v1
Checksum:iB018C8300962FA14
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF033538 mRNA. Translation: AAD10253.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF033538 mRNA. Translation: AAD10253.1 .

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
3P9C X-ray 1.80 A 1-360 [» ]
3P9I X-ray 1.85 A/B/C/D 1-360 [» ]
3P9K X-ray 2.25 A/B/C/D 1-360 [» ]
ProteinModelPortali Q9ZTU2.
SMRi Q9ZTU2. Positions 2-360.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

Gramenei Q9ZTU2.

Miscellaneous databases

EvolutionaryTracei Q9ZTU2.

Family and domain databases

Gene3Di 1.10.10.10. 1 hit.
3.40.50.150. 1 hit.
InterProi IPR016461. COMT.
IPR001077. O_MeTrfase_2.
IPR012967. Plant_MeTrfase_dimerisation.
IPR029063. SAM-dependent_MTases-like.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view ]
Pfami PF08100. Dimerisation. 1 hit.
PF00891. Methyltransf_2. 1 hit.
[Graphical view ]
PIRSFi PIRSF005739. O-mtase. 1 hit.
SUPFAMi SSF53335. SSF53335. 1 hit.
PROSITEi PS51588. SAM_MT_COMT. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "cDNA cloning and differential expression of three caffeic acid O-methyltransferase homologues from Lolium perenne."
    Heath R.L., Huxley H., Stone B.A., Spangenberg G.
    Submitted (NOV-1997) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "Structure-function analyses of a caffeic acid O-methyltransferase from perennial ryegrass reveal the molecular basis for substrate preference."
    Louie G.V., Bowman M.E., Tu Y., Mouradov A., Spangenberg G., Noel J.P.
    Plant Cell 22:4114-4127(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.80 ANGSTROMS) IN COMPLEX WITH S-ADENOSYL-L-HOMOCYSTEINE.

Entry informationi

Entry nameiQ9ZTU2_LOLPR
AccessioniPrimary (citable) accession number: Q9ZTU2
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 1999
Last sequence update: May 1, 1999
Last modified: October 29, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported

External Data

Dasty 3