Q9ZT48 (ATE1_ARATH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Arginyl-tRNA--protein transferase 1
Short name=Arginyltransferase 1
Short name=R-transferase 1
EC=2.3.2.8

Alternative name(s):
Arginine-tRNA--protein transferase 1

Gene names

Name:	ATE1
Ordered Locus Names:	At5g05700
ORF Names:	MJJ3.10

Organism

Arabidopsis thaliana (Mouse-ear cress)

Taxonomic identifier

3702 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis

Protein attributes

Sequence length	632 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein. This arginylation is required for degradation of the protein via the ubiquitin pathway. Does not arginylate cysteine residues By similarity.
Catalytic activity	L-arginyl-tRNA + protein = tRNA + L-arginyl-protein.
Sequence similarities	Belongs to the R-transferase family.

Ontologies

Keywords
Biological process	Ubl conjugation pathway
Molecular function	Acyltransferase Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	leaf senescence Inferred from mutant phenotype. Source: TAIR protein arginylation Inferred from electronic annotation. Source: InterPro regulation of lipid catabolic process Inferred from genetic interaction. Source: TAIR regulation of seed germination Inferred from genetic interaction. Source: TAIR response to abscisic acid stimulus Inferred from genetic interaction. Source: TAIR
Molecular function	arginyltransferase activity Inferred from mutant phenotype. Source: TAIR
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 632	632	Arginyl-tRNA--protein transferase 1		PRO_0000195091
Experimental info
	Sequence conflict	546 – 548	3	Missing in AAD12368. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	Q9ZT48 [UniParc]. Last modified February 21, 2001. Version 2. Checksum: F955FFD7C30182E9	FASTA	632	71,541
	10 20 30 40 50 60 MSLKNDASSS HDGGSNRESV IDDHGRRKST CGYCKSPARS SISHGLSAQT LTVYDYQALI 70 80 90 100 110 120 DRGWRRSGTY LYKHEMDKTC CPPYTIRLKA SDFVPTKEQQ RVSRRLERFL DGKLDVQPRE 130 140 150 160 170 180 QRGASSSGDV SDTRRKTLGA AKSEENKKVE AVMDDLSKNI DQAVQLCIRS GEFPSNMQIP 190 200 210 220 230 240 KASVKKVFCA RRKKLAEGTE QILYTSNIAF PIAAAIKRIQ TSEKEGINSA EGNRLSPETI 250 260 270 280 290 300 SEMLLSAMHK VGETPDVSIK VCKGHINFLS SAKDSFSDRD VVPNGNISRG ANSLDGSETL 310 320 330 340 350 360 HAKKDSENHQ ARKRKLEIHL KRSSFDPEEH ELYKRYQLKV HNDKPGHVVE SSYRRFLVDS 370 380 390 400 410 420 PLIDVQPSGD EKVPPCGFGS FHQQYRIDGR LIAVGVVDIL PKCLSSVYLF WDPDYAFLSL 430 440 450 460 470 480 GKYSAIQEIN WVIENQARCP SLQYYYLGYY IHSCSKMRYK AAYRPSELLC PLRFQWVPFE 490 500 510 520 530 540 VARPMLDKKP YVILSDIAIS HNQCSLLAGA SETLVEPAAS EHEDMEQGET NDNFMGCSDE 550 560 570 580 590 600 DEDEDEDDDD DDDDDEEMYE TESEDSHIES DPGSKDNDIN NILIGLYGSQ YRYKEMRQII 610 620 630 TPVGRKQLEP MLQSYRKVVG AELSERMVYE IN

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Alternative splicing results in differential expression, activity, and localization of the two forms of arginyl-tRNA-protein transferase, a component of the N-end rule pathway." Kwon Y.T., Kashina A.S., Varshavsky A. Mol. Cell. Biol. 19:182-193(1999) [PubMed: 9858543] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[2]	"Structural analysis of Arabidopsis thaliana chromosome 5. I. Sequence features of the 1.6 Mb regions covered by twenty physically assigned P1 clones." Sato S., Kotani H., Nakamura Y., Kaneko T., Asamizu E., Fukami M., Miyajima N., Tabata S. DNA Res. 4:215-230(1997) [PubMed: 9330910] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Columbia.
[3]	The Arabidopsis Information Resource (TAIR) Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: cv. Columbia.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF079100 mRNA. Translation: AAD12368.1. AB005237 Genomic DNA. Translation: BAB09664.1. CP002688 Genomic DNA. Translation: AED90912.1.
IPI	IPI00536580.
PIR	T51729.
RefSeq	NP_196189.1. NM_120652.4.
UniGene	At.20652.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q9ZT48.
Proteomic databases
PRIDE	Q9ZT48.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblPlants	AT5G05700.1; AT5G05700.1; AT5G05700.
GeneID	830454.
GenomeReviews	Gene locus AT5G05700 in contig BA000015_GR.
KEGG	ath:AT5G05700.
NMPDR	fig|3702.1.peg.22683.
Organism-specific databases
TAIR	At5g05700.
Phylogenomic databases
GeneTree	EPGT00050000017964.
HOGENOM	HBG714174.
InParanoid	Q9ZT48.
OMA	HNDNPAR.
PhylomeDB	Q9ZT48.
ProtClustDB	CLSN2684396.
Gene expression databases
Genevestigator	Q9ZT48.
GermOnline	AT5G05700. Arabidopsis thaliana.
Family and domain databases
InterPro	IPR016181. Acyl_CoA_acyltransferase. IPR017137. Arg-tRNA-P_Trfase_1_euk. IPR007472. Arg-tRNA-P_Trfase_C. IPR007471. Arg_tRNA_PTrfase_N. [Graphical view]
KO	K00685.
Pfam	PF04377. ATE_C. 1 hit. PF04376. ATE_N. 1 hit. [Graphical view]
PIRSF	PIRSF037207. ATE1_euk. 1 hit.
SUPFAM	SSF55729. Acyl_CoA_acyltransferase. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ATE1_ARATH

Accession

Primary (citable) accession number: Q9ZT48

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 21, 2001
Last sequence update:	February 21, 2001
Last modified:	November 16, 2011
This is version 69 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program