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Q9ZSE4

- PP2A_HEVBR

UniProt

Q9ZSE4 - PP2A_HEVBR

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Protein

Serine/threonine-protein phosphatase PP2A catalytic subunit

Gene
PP2A
Organism
Hevea brasiliensis (Para rubber tree) (Siphonia brasiliensis)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Binds 2 manganese ions per subunit By similarity.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi54 – 541Manganese 1 By similarity
Metal bindingi56 – 561Manganese 1 By similarity
Metal bindingi82 – 821Manganese 1 By similarity
Metal bindingi82 – 821Manganese 2 By similarity
Metal bindingi114 – 1141Manganese 2 By similarity
Active sitei115 – 1151Proton donor By similarity
Metal bindingi164 – 1641Manganese 2 By similarity
Metal bindingi238 – 2381Manganese 2 By similarity

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. phosphoprotein phosphatase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Ligandi

Manganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Serine/threonine-protein phosphatase PP2A catalytic subunit (EC:3.1.3.16)
Gene namesi
Name:PP2A
OrganismiHevea brasiliensis (Para rubber tree) (Siphonia brasiliensis)
Taxonomic identifieri3981 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsMalpighialesEuphorbiaceaeCrotonoideaeMicrandreaeHevea

Subcellular locationi

Cytoplasm By similarity

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 306306Serine/threonine-protein phosphatase PP2A catalytic subunitPRO_0000058859Add
BLAST

Proteomic databases

PRIDEiQ9ZSE4.

Expressioni

Tissue specificityi

Expressed at the same level in latex as in leaves.

Structurei

3D structure databases

ProteinModelPortaliQ9ZSE4.
SMRiQ9ZSE4. Positions 6-306.

Family & Domainsi

Sequence similaritiesi

Family and domain databases

Gene3Di3.60.21.10. 1 hit.
InterProiIPR004843. Calcineurin-like_PHP_apaH.
IPR029052. Metallo-depent_PP-like.
IPR006186. Ser/Thr-sp_prot-phosphatase.
[Graphical view]
PfamiPF00149. Metallophos. 1 hit.
[Graphical view]
PRINTSiPR00114. STPHPHTASE.
SMARTiSM00156. PP2Ac. 1 hit.
[Graphical view]
SUPFAMiSSF56300. SSF56300. 1 hit.
PROSITEiPS00125. SER_THR_PHOSPHATASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9ZSE4-1 [UniParc]FASTAAdd to Basket

« Hide

MPSHGDLDRQ IEHLMECKPL PEARGQTLCD QARAILVEEW NVQPVKCPVT    50
VCGDIHGQFY DLIELFRIGG NAPDTNYLFM GDYVDRGYYS VETVTLLVAL 100
KVRYRDRITI LRGNHESRQI TQVYGFYDEC LRKYGNANVW KYFTDLFDYL 150
PLTALIESQI FCLHGGLSPS LDTLDNIRAL DRIQEVPHEG PMCDLLWSDP 200
DDRCGWGISP RGAGYTFGQD IAAQFNHTNG LTLISRAHQL VMEGYNWCQE 250
KNVVTVFSAP NYCYRCGIMA AILEIGENMA QNFLQFDPAP RQIEPDTTRK 300
TPDYFL 306
Length:306
Mass (Da):34,969
Last modified:May 1, 1999 - v1
Checksum:iEFBE7F9DF4EB4A61
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF107464 mRNA. Translation: AAD09953.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF107464 mRNA. Translation: AAD09953.1 .

3D structure databases

ProteinModelPortali Q9ZSE4.
SMRi Q9ZSE4. Positions 6-306.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi Q9ZSE4.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

Gene3Di 3.60.21.10. 1 hit.
InterProi IPR004843. Calcineurin-like_PHP_apaH.
IPR029052. Metallo-depent_PP-like.
IPR006186. Ser/Thr-sp_prot-phosphatase.
[Graphical view ]
Pfami PF00149. Metallophos. 1 hit.
[Graphical view ]
PRINTSi PR00114. STPHPHTASE.
SMARTi SM00156. PP2Ac. 1 hit.
[Graphical view ]
SUPFAMi SSF56300. SSF56300. 1 hit.
PROSITEi PS00125. SER_THR_PHOSPHATASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Isolation of a cDNA encoding a type 2A serine/threonine protein phosphatase (PP2A) from Hevea brasiliensis."
    Shin D.H., Han K.-H.
    Plant Gene Register PGR99-011
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Entry informationi

Entry nameiPP2A_HEVBR
AccessioniPrimary (citable) accession number: Q9ZSE4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: May 1, 1999
Last modified: June 11, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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