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Q9ZRR8

- CHS1_CASGL

UniProt

Q9ZRR8 - CHS1_CASGL

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Protein
Chalcone synthase
Gene
CHS1
Organism
Casuarina glauca (Swamp oak)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at transcript leveli

Functioni

The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.

Catalytic activityi

3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei164 – 1641 By similarity

GO - Molecular functioni

  1. naringenin-chalcone synthase activity Source: UniProtKB-EC

GO - Biological processi

  1. flavonoid biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Acyltransferase, Transferase

Keywords - Biological processi

Flavonoid biosynthesis

Enzyme and pathway databases

UniPathwayiUPA00154.

Names & Taxonomyi

Protein namesi
Recommended name:
Chalcone synthase (EC:2.3.1.74)
Alternative name(s):
Naringenin-chalcone synthase
Gene namesi
Name:CHS1
OrganismiCasuarina glauca (Swamp oak)
Taxonomic identifieri3522 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFagalesCasuarinaceaeCasuarina

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 389389Chalcone synthase
PRO_0000215964Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ9ZRR8.
SMRiQ9ZRR8. Positions 3-387.

Family & Domainsi

Sequence similaritiesi

Family and domain databases

Gene3Di3.40.47.10. 2 hits.
InterProiIPR012328. Chalcone/stilbene_synth_C.
IPR018088. Chalcone/stilbene_synthase_AS.
IPR001099. Chalcone/stilbene_synthase_N.
IPR011141. Polyketide_synthase_type-III.
IPR016039. Thiolase-like.
IPR016038. Thiolase-like_subgr.
[Graphical view]
PfamiPF02797. Chal_sti_synt_C. 1 hit.
PF00195. Chal_sti_synt_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000451. PKS_III. 1 hit.
SUPFAMiSSF53901. SSF53901. 2 hits.
PROSITEiPS00441. CHALCONE_SYNTH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9ZRR8-1 [UniParc]FASTAAdd to Basket

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MVTVEEVRKA QRAEGPATVL AIGTATPPNC LDQSTYPDYY FRITNSEHKT    50
ELKEKFQRMC DKSMIKKRYM YLTEEILKEH PNMCAYMAPS LDARQDMVVV 100
EIPKLGKEAA VKAIKEWGQP KSKITHLVFC TTSGVDMPGA DYQLTKLLGL 150
RPSVKRLMMY QQGCFAGGTV LRLAKDLAEN NRGARVLVVC SEITAVTFRG 200
PSDTHLDSLV GQALFGDGAA AIIVGADPLP EVEKPLFEVV STAQTILPDS 250
DGAIDGHLRE VGVTFHLLKD VPGLISKNIE KSLVEAFQPL GISDWNSLFW 300
IAHPGGPAIL DQVEEKLALK PEKLGATRHV LSEYGNMSSA CVLFILDEMR 350
RKSAEKGLKT TGEGLDWGVL FGFGPGLTVE TVVLHSLTT 389
Length:389
Mass (Da):42,603
Last modified:May 1, 1999 - v1
Checksum:i185BE6F345EFA7DD
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ132323 mRNA. Translation: CAA10641.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ132323 mRNA. Translation: CAA10641.1 .

3D structure databases

ProteinModelPortali Q9ZRR8.
SMRi Q9ZRR8. Positions 3-387.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Enzyme and pathway databases

UniPathwayi UPA00154 .

Family and domain databases

Gene3Di 3.40.47.10. 2 hits.
InterProi IPR012328. Chalcone/stilbene_synth_C.
IPR018088. Chalcone/stilbene_synthase_AS.
IPR001099. Chalcone/stilbene_synthase_N.
IPR011141. Polyketide_synthase_type-III.
IPR016039. Thiolase-like.
IPR016038. Thiolase-like_subgr.
[Graphical view ]
Pfami PF02797. Chal_sti_synt_C. 1 hit.
PF00195. Chal_sti_synt_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF000451. PKS_III. 1 hit.
SUPFAMi SSF53901. SSF53901. 2 hits.
PROSITEi PS00441. CHALCONE_SYNTH. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Flavan-containing cells delimit Frankia infected compartments in Casuarina glauca nodules."
    Laplaze L., Gherbi H., Frutz T., Pawlowski K., Franche C., Macheix J.J., Auguy F., Bogusz D., Duhoux E.
    Plant Physiol. 121:113-122(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Tissue: Root nodule.

Entry informationi

Entry nameiCHS1_CASGL
AccessioniPrimary (citable) accession number: Q9ZRR8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 8, 2000
Last sequence update: May 1, 1999
Last modified: February 19, 2014
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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