Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Putative peroxisomal acyl-coenzyme A oxidase 1.2

Gene

ACX1.2

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs.By similarity

Catalytic activityi

Acyl-CoA + O2 = trans-2,3-dehydroacyl-CoA + H2O2.

Cofactori

FADBy similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi399 – 4046FADBy similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Fatty acid metabolism, Lipid metabolism

Keywords - Ligandi

FAD, Flavoprotein

Enzyme and pathway databases

BRENDAi1.3.3.6. 399.
ReactomeiR-ATH-193368. Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol.
R-ATH-2046106. alpha-linolenic acid (ALA) metabolism.
R-ATH-389887. Beta-oxidation of pristanoyl-CoA.
R-ATH-390247. Beta-oxidation of very long chain fatty acids.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative peroxisomal acyl-coenzyme A oxidase 1.2 (EC:1.3.3.6)
Gene namesi
Name:ACX1.2
Ordered Locus Names:At2g35690
ORF Names:T20F21.12
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 2

Organism-specific databases

TAIRiAT2G35690.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Peroxisome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 664664Putative peroxisomal acyl-coenzyme A oxidase 1.2PRO_0000204690Add
BLAST

Proteomic databases

PaxDbiQ9ZQP2.
PRIDEiQ9ZQP2.

Expressioni

Inductioni

Not induced by wounding.1 Publication

Gene expression databases

GenevisibleiQ9ZQP2. AT.

Interactioni

Protein-protein interaction databases

BioGridi3483. 1 interaction.
STRINGi3702.AT2G35690.1.

Structurei

3D structure databases

ProteinModelPortaliQ9ZQP2.
SMRiQ9ZQP2. Positions 2-659.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi662 – 6643Microbody targeting signalSequence analysis

Sequence similaritiesi

Belongs to the acyl-CoA oxidase family.Curated

Phylogenomic databases

eggNOGiKOG0136. Eukaryota.
COG1960. LUCA.
HOGENOMiHOG000181256.
InParanoidiQ9ZQP2.
KOiK00232.
OMAiNTGIEVC.
OrthoDBiEOG093603O2.
PhylomeDBiQ9ZQP2.

Family and domain databases

Gene3Di1.10.540.10. 1 hit.
InterProiIPR029320. Acyl-CoA_ox_N.
IPR006091. Acyl-CoA_Oxase/DH_cen-dom.
IPR012258. Acyl-CoA_oxidase.
IPR002655. Acyl-CoA_oxidase_C.
IPR009075. AcylCo_DH/oxidase_C.
IPR013786. AcylCoA_DH/ox_N.
IPR009100. AcylCoA_DH/oxidase_NM_dom.
[Graphical view]
PfamiPF01756. ACOX. 1 hit.
PF02770. Acyl-CoA_dh_M. 1 hit.
PF14749. Acyl-CoA_ox_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000168. Acyl-CoA_oxidase. 1 hit.
SUPFAMiSSF47203. SSF47203. 2 hits.
SSF56645. SSF56645. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9ZQP2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MERVDHLADE RNKAEFNVDD MKIVWAGSRH AFDVSNRMSR LVANDPVFEK
60 70 80 90 100
SKRAVMSRKE LFKNTLRKSV HAWKLINELR LSDEEGLKLR SFMDQPGFLD
110 120 130 140 150
LHWGMFVPAI KGQGTEQQQQ KWLSLATKMQ IIGCYAQTEL GHGSNVQGLE
160 170 180 190 200
TTATFDPKTD QFIIHSPTQT SSKWWPGGLG KVSTHAVIYA RLITNGKDHG
210 220 230 240 250
VHGFIVQLRS LDDHSPLPGI TVGDIGMKFG NGAYNSMDNG FLMFDHFRIP
260 270 280 290 300
RDQMLMRLSK VTREGKYVAS DVPRQLVYGT MVYVRQSIVS NASTALARAV
310 320 330 340 350
CIATRYSAVR RQFGSHDGGI ETQVINYKTQ QNRLFPLLAS AYAFRFVGEW
360 370 380 390 400
LKWLYTDVTK RLEASDFATL PEAHACTAGL KSMTTSATSD GIEECRKLCG
410 420 430 440 450
GHGYLWCSGL PELFAVYVPA CTYEGDNVVL QLQVARFLMK TVSQLGSGKA
460 470 480 490 500
PSGTTAYMGR AKHLLQCSSG VRNARDWLNP GMVLEAFEAR ALRMAVTCAN
510 520 530 540 550
NLSKFENQEQ GFSELLADLV EAATAHCQLI VVSKFIAKVE GDIEGKGVKK
560 570 580 590 600
QLKNLCYIYA LYLLHKHLGD FLSTNSVTPE QASLANQQLR SLYSQVRPNA
610 620 630 640 650
VALVDAFDYT DQYLGSVLGR YDGNVYPKLF EEALKDPLND SVVPDGYREY
660
IRPLIKQRFR SAKL
Length:664
Mass (Da):74,298
Last modified:May 1, 1999 - v1
Checksum:iE523BC625944A7AA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC006068 Genomic DNA. Translation: AAD15446.1.
CP002685 Genomic DNA. Translation: AEC09145.1.
AY074357 mRNA. Translation: AAL67053.1.
AY096691 mRNA. Translation: AAM20325.1.
PIRiG84771.
RefSeqiNP_181112.1. NM_129124.3.
UniGeneiAt.37640.

Genome annotation databases

EnsemblPlantsiAT2G35690.1; AT2G35690.1; AT2G35690.
GeneIDi818138.
GrameneiAT2G35690.1; AT2G35690.1; AT2G35690.
KEGGiath:AT2G35690.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC006068 Genomic DNA. Translation: AAD15446.1.
CP002685 Genomic DNA. Translation: AEC09145.1.
AY074357 mRNA. Translation: AAL67053.1.
AY096691 mRNA. Translation: AAM20325.1.
PIRiG84771.
RefSeqiNP_181112.1. NM_129124.3.
UniGeneiAt.37640.

3D structure databases

ProteinModelPortaliQ9ZQP2.
SMRiQ9ZQP2. Positions 2-659.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi3483. 1 interaction.
STRINGi3702.AT2G35690.1.

Proteomic databases

PaxDbiQ9ZQP2.
PRIDEiQ9ZQP2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT2G35690.1; AT2G35690.1; AT2G35690.
GeneIDi818138.
GrameneiAT2G35690.1; AT2G35690.1; AT2G35690.
KEGGiath:AT2G35690.

Organism-specific databases

TAIRiAT2G35690.

Phylogenomic databases

eggNOGiKOG0136. Eukaryota.
COG1960. LUCA.
HOGENOMiHOG000181256.
InParanoidiQ9ZQP2.
KOiK00232.
OMAiNTGIEVC.
OrthoDBiEOG093603O2.
PhylomeDBiQ9ZQP2.

Enzyme and pathway databases

BRENDAi1.3.3.6. 399.
ReactomeiR-ATH-193368. Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol.
R-ATH-2046106. alpha-linolenic acid (ALA) metabolism.
R-ATH-389887. Beta-oxidation of pristanoyl-CoA.
R-ATH-390247. Beta-oxidation of very long chain fatty acids.

Miscellaneous databases

PROiQ9ZQP2.

Gene expression databases

GenevisibleiQ9ZQP2. AT.

Family and domain databases

Gene3Di1.10.540.10. 1 hit.
InterProiIPR029320. Acyl-CoA_ox_N.
IPR006091. Acyl-CoA_Oxase/DH_cen-dom.
IPR012258. Acyl-CoA_oxidase.
IPR002655. Acyl-CoA_oxidase_C.
IPR009075. AcylCo_DH/oxidase_C.
IPR013786. AcylCoA_DH/ox_N.
IPR009100. AcylCoA_DH/oxidase_NM_dom.
[Graphical view]
PfamiPF01756. ACOX. 1 hit.
PF02770. Acyl-CoA_dh_M. 1 hit.
PF14749. Acyl-CoA_ox_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000168. Acyl-CoA_oxidase. 1 hit.
SUPFAMiSSF47203. SSF47203. 2 hits.
SSF56645. SSF56645. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiACO12_ARATH
AccessioniPrimary (citable) accession number: Q9ZQP2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 29, 2005
Last sequence update: May 1, 1999
Last modified: September 7, 2016
This is version 112 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.