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Protein

Putative peroxisomal acyl-coenzyme A oxidase 1.2

Gene

ACX1.2

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs.By similarity

Catalytic activityi

Acyl-CoA + O2 = trans-2,3-dehydroacyl-CoA + H2O2.

Cofactori

FADBy similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi399 – 404FADBy similarity6

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
Biological processFatty acid metabolism, Lipid metabolism
LigandFAD, Flavoprotein

Enzyme and pathway databases

BRENDAi1.3.3.6 399
ReactomeiR-ATH-193368 Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
R-ATH-2046106 alpha-linolenic acid (ALA) metabolism
R-ATH-389887 Beta-oxidation of pristanoyl-CoA
R-ATH-390247 Beta-oxidation of very long chain fatty acids

Names & Taxonomyi

Protein namesi
Recommended name:
Putative peroxisomal acyl-coenzyme A oxidase 1.2 (EC:1.3.3.6)
Gene namesi
Name:ACX1.2
Ordered Locus Names:At2g35690
ORF Names:T20F21.12
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 2

Organism-specific databases

AraportiAT2G35690
TAIRilocus:2058779 AT2G35690

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Peroxisome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002046901 – 664Putative peroxisomal acyl-coenzyme A oxidase 1.2Add BLAST664

Proteomic databases

PaxDbiQ9ZQP2
PRIDEiQ9ZQP2

Expressioni

Inductioni

Not induced by wounding.1 Publication

Gene expression databases

ExpressionAtlasiQ9ZQP2 baseline and differential
GenevisibleiQ9ZQP2 AT

Interactioni

Protein-protein interaction databases

BioGridi3483, 1 interactor
STRINGi3702.AT2G35690.1

Structurei

3D structure databases

ProteinModelPortaliQ9ZQP2
SMRiQ9ZQP2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi662 – 664Microbody targeting signalSequence analysis3

Sequence similaritiesi

Belongs to the acyl-CoA oxidase family.Curated

Phylogenomic databases

eggNOGiKOG0136 Eukaryota
COG1960 LUCA
HOGENOMiHOG000181256
InParanoidiQ9ZQP2
KOiK00232
OMAiMASVNQG
OrthoDBiEOG093603O2
PhylomeDBiQ9ZQP2

Family and domain databases

Gene3Di1.10.540.10, 1 hit
InterProiView protein in InterPro
IPR029320 Acyl-CoA_ox_N
IPR006091 Acyl-CoA_Oxase/DH_cen-dom
IPR012258 Acyl-CoA_oxidase
IPR002655 Acyl-CoA_oxidase_C
IPR036250 AcylCo_DH-like_C
IPR037069 AcylCoA_DH/ox_N_sf
IPR009100 AcylCoA_DH/oxidase_NM_dom
PfamiView protein in Pfam
PF01756 ACOX, 1 hit
PF02770 Acyl-CoA_dh_M, 1 hit
PF14749 Acyl-CoA_ox_N, 1 hit
PIRSFiPIRSF000168 Acyl-CoA_oxidase, 1 hit
SUPFAMiSSF47203 SSF47203, 2 hits
SSF56645 SSF56645, 1 hit

Sequencei

Sequence statusi: Complete.

Q9ZQP2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MERVDHLADE RNKAEFNVDD MKIVWAGSRH AFDVSNRMSR LVANDPVFEK
60 70 80 90 100
SKRAVMSRKE LFKNTLRKSV HAWKLINELR LSDEEGLKLR SFMDQPGFLD
110 120 130 140 150
LHWGMFVPAI KGQGTEQQQQ KWLSLATKMQ IIGCYAQTEL GHGSNVQGLE
160 170 180 190 200
TTATFDPKTD QFIIHSPTQT SSKWWPGGLG KVSTHAVIYA RLITNGKDHG
210 220 230 240 250
VHGFIVQLRS LDDHSPLPGI TVGDIGMKFG NGAYNSMDNG FLMFDHFRIP
260 270 280 290 300
RDQMLMRLSK VTREGKYVAS DVPRQLVYGT MVYVRQSIVS NASTALARAV
310 320 330 340 350
CIATRYSAVR RQFGSHDGGI ETQVINYKTQ QNRLFPLLAS AYAFRFVGEW
360 370 380 390 400
LKWLYTDVTK RLEASDFATL PEAHACTAGL KSMTTSATSD GIEECRKLCG
410 420 430 440 450
GHGYLWCSGL PELFAVYVPA CTYEGDNVVL QLQVARFLMK TVSQLGSGKA
460 470 480 490 500
PSGTTAYMGR AKHLLQCSSG VRNARDWLNP GMVLEAFEAR ALRMAVTCAN
510 520 530 540 550
NLSKFENQEQ GFSELLADLV EAATAHCQLI VVSKFIAKVE GDIEGKGVKK
560 570 580 590 600
QLKNLCYIYA LYLLHKHLGD FLSTNSVTPE QASLANQQLR SLYSQVRPNA
610 620 630 640 650
VALVDAFDYT DQYLGSVLGR YDGNVYPKLF EEALKDPLND SVVPDGYREY
660
IRPLIKQRFR SAKL
Length:664
Mass (Da):74,298
Last modified:May 1, 1999 - v1
Checksum:iE523BC625944A7AA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC006068 Genomic DNA Translation: AAD15446.1
CP002685 Genomic DNA Translation: AEC09145.1
AY074357 mRNA Translation: AAL67053.1
AY096691 mRNA Translation: AAM20325.1
PIRiG84771
RefSeqiNP_181112.1, NM_129124.4
UniGeneiAt.37640

Genome annotation databases

EnsemblPlantsiAT2G35690.1; AT2G35690.1; AT2G35690
GeneIDi818138
GrameneiAT2G35690.1; AT2G35690.1; AT2G35690
KEGGiath:AT2G35690

Similar proteinsi

Entry informationi

Entry nameiACO12_ARATH
AccessioniPrimary (citable) accession number: Q9ZQP2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 29, 2005
Last sequence update: May 1, 1999
Last modified: April 25, 2018
This is version 124 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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