Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

UDP-glycosyltransferase 73B5

Gene

UGT73B5

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at transcript leveli

Functioni

Possesses quercetin 3-O-glucosyltransferase activity in vitro. Involved in stress or defense responses.2 Publications

Catalytic activityi

UDP-glucose + a flavonol = UDP + a flavonol 3-O-D-glucoside.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei297 – 2971UDP-glucoseBy similarity

GO - Molecular functioni

GO - Biological processi

  • defense response Source: UniProtKB-KW
  • flavonoid biosynthetic process Source: GO_Central
  • flavonoid glucuronidation Source: GO_Central
  • response to other organism Source: TAIR
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Keywords - Biological processi

Plant defense

Enzyme and pathway databases

BioCyciARA:GQT-2822-MONOMER.

Protein family/group databases

CAZyiGT1. Glycosyltransferase Family 1.

Names & Taxonomyi

Protein namesi
Recommended name:
UDP-glycosyltransferase 73B5 (EC:2.4.1.-)
Alternative name(s):
Flavonol 3-O-glucosyltransferase UGT73B5 (EC:2.4.1.91)
Gene namesi
Name:UGT73B5
Ordered Locus Names:At2g15480
ORF Names:F9O13.3
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
ProteomesiUP000006548 Componenti: Chromosome 2

Organism-specific databases

TAIRiAT2G15480.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Disruption phenotypei

Decreased resistance to avirulent strains of P.syringae.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 484484UDP-glycosyltransferase 73B5PRO_0000409080Add
BLAST

Proteomic databases

PaxDbiQ9ZQG4.
PRIDEiQ9ZQG4.

Expressioni

Tissue specificityi

Expressed in roots and senescent leaves.1 Publication

Inductioni

Induced by pathogen infection, H2O2 and salicylic acid.1 Publication

Gene expression databases

ExpressionAtlasiQ9ZQG4. baseline and differential.
GenevestigatoriQ9ZQG4.

Interactioni

Protein-protein interaction databases

STRINGi3702.AT2G15480.1-P.

Structurei

3D structure databases

ProteinModelPortaliQ9ZQG4.
SMRiQ9ZQG4. Positions 9-478.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni356 – 3583UDP-glucose bindingBy similarity
Regioni373 – 3819UDP-glucose bindingBy similarity
Regioni395 – 3984UDP-glucose bindingBy similarity

Sequence similaritiesi

Belongs to the UDP-glycosyltransferase family.Curated

Phylogenomic databases

eggNOGiNOG244246.
HOGENOMiHOG000237565.
InParanoidiQ9ZQG4.
PhylomeDBiQ9ZQG4.

Family and domain databases

InterProiIPR002213. UDP_glucos_trans.
[Graphical view]
PANTHERiPTHR11926. PTHR11926. 1 hit.
PfamiPF00201. UDPGT. 1 hit.
[Graphical view]
PROSITEiPS00375. UDPGT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

This entry describes 1 isoform i produced by alternative splicing. AlignAdd to basket

Note: A number of isoforms are produced. According to EST sequences.

Isoform 1 (identifier: Q9ZQG4-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MNREVSERIH ILFFPFMAQG HMIPILDMAK LFSRRGAKST LLTTPINAKI
60 70 80 90 100
FEKPIEAFKN QNPDLEIGIK IFNFPCVELG LPEGCENADF INSYQKSDSG
110 120 130 140 150
DLFLKFLFST KYMKQQLESF IETTKPSALV ADMFFPWATE SAEKLGVPRL
160 170 180 190 200
VFHGTSFFSL CCSYNMRIHK PHKKVATSST PFVIPGLPGD IVITEDQANV
210 220 230 240 250
AKEETPMGKF MKEVRESETN SFGVLVNSFY ELESAYADFY RSFVAKRAWH
260 270 280 290 300
IGPLSLSNRE LGEKARRGKK ANIDEQECLK WLDSKTPGSV VYLSFGSGTN
310 320 330 340 350
FTNDQLLEIA FGLEGSGQSF IWVVRKNENQ GDNEEWLPEG FKERTTGKGL
360 370 380 390 400
IIPGWAPQVL ILDHKAIGGF VTHCGWNSAI EGIAAGLPMV TWPMGAEQFY
410 420 430 440 450
NEKLLTKVLR IGVNVGATEL VKKGKLISRA QVEKAVREVI GGEKAEERRL
460 470 480
WAKKLGEMAK AAVEEGGSSY NDVNKFMEEL NGRK
Length:484
Mass (Da):54,184
Last modified:May 1, 1999 - v1
Checksum:iB94342034C3394A6
GO

Sequence cautioni

The sequence AAM91525.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC006248 Genomic DNA. Translation: AAD17392.1.
CP002685 Genomic DNA. Translation: AEC06405.1.
AY128322 mRNA. Translation: AAM91525.1. Different initiation.
BT015865 mRNA. Translation: AAU94428.1.
PIRiE84529.
RefSeqiNP_179150.3. NM_127108.3. [Q9ZQG4-1]
UniGeneiAt.40404.

Genome annotation databases

EnsemblPlantsiAT2G15480.1; AT2G15480.1; AT2G15480. [Q9ZQG4-1]
GeneIDi816040.
KEGGiath:AT2G15480.

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC006248 Genomic DNA. Translation: AAD17392.1.
CP002685 Genomic DNA. Translation: AEC06405.1.
AY128322 mRNA. Translation: AAM91525.1. Different initiation.
BT015865 mRNA. Translation: AAU94428.1.
PIRiE84529.
RefSeqiNP_179150.3. NM_127108.3. [Q9ZQG4-1]
UniGeneiAt.40404.

3D structure databases

ProteinModelPortaliQ9ZQG4.
SMRiQ9ZQG4. Positions 9-478.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi3702.AT2G15480.1-P.

Protein family/group databases

CAZyiGT1. Glycosyltransferase Family 1.

Proteomic databases

PaxDbiQ9ZQG4.
PRIDEiQ9ZQG4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT2G15480.1; AT2G15480.1; AT2G15480. [Q9ZQG4-1]
GeneIDi816040.
KEGGiath:AT2G15480.

Organism-specific databases

TAIRiAT2G15480.

Phylogenomic databases

eggNOGiNOG244246.
HOGENOMiHOG000237565.
InParanoidiQ9ZQG4.
PhylomeDBiQ9ZQG4.

Enzyme and pathway databases

BioCyciARA:GQT-2822-MONOMER.

Miscellaneous databases

PROiQ9ZQG4.

Gene expression databases

ExpressionAtlasiQ9ZQG4. baseline and differential.
GenevestigatoriQ9ZQG4.

Family and domain databases

InterProiIPR002213. UDP_glucos_trans.
[Graphical view]
PANTHERiPTHR11926. PTHR11926. 1 hit.
PfamiPF00201. UDPGT. 1 hit.
[Graphical view]
PROSITEiPS00375. UDPGT. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  2. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  3. "Empirical analysis of transcriptional activity in the Arabidopsis genome."
    Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.
    , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
    Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 35-484.
    Strain: cv. Columbia.
  4. "Arabidopsis ORF clones."
    Kim C.J., Chen H., Cheuk R.F., Shinn P., Ecker J.R.
    Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 113-484.
    Strain: cv. Columbia.
  5. "Phylogenetic analysis of the UDP-glycosyltransferase multigene family of Arabidopsis thaliana."
    Li Y., Baldauf S., Lim E.K., Bowles D.J.
    J. Biol. Chem. 276:4338-4343(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY.
  6. "Arabidopsis glycosyltransferases as biocatalysts in fermentation for regioselective synthesis of diverse quercetin glucosides."
    Lim E.K., Ashford D.A., Hou B., Jackson R.G., Bowles D.J.
    Biotechnol. Bioeng. 87:623-631(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.
  7. "Pathogen-responsive expression of glycosyltransferase genes UGT73B3 and UGT73B5 is necessary for resistance to Pseudomonas syringae pv tomato in Arabidopsis."
    Langlois-Meurinne M., Gachon C.M., Saindrenan P.
    Plant Physiol. 139:1890-1901(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, TISSUE SPECIFICITY, DISRUPTION PHENOTYPE, INDUCTION BY PATHOGEN AND SALICYLIC ACID.

Entry informationi

Entry nameiU73B5_ARATH
AccessioniPrimary (citable) accession number: Q9ZQG4
Secondary accession number(s): Q8L7Q5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 31, 2011
Last sequence update: May 1, 1999
Last modified: April 29, 2015
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.