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Q9ZPB7

- AL7A1_MALDO

UniProt

Q9ZPB7 - AL7A1_MALDO

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Protein
Aldehyde dehydrogenase family 7 member A1
Gene
N/A
Organism
Malus domestica (Apple) (Pyrus malus)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at protein leveli

Functioni

May play a role in fruit development.1 Publication

Catalytic activityi

An aldehyde + NAD+ + H2O = a carboxylate + NADH.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sitei165 – 1651Transition state stabilizer By similarity
Active sitei266 – 2661Proton acceptor By similarityBy similarity
Active sitei300 – 3001Nucleophile By similarityBy similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi244 – 2496NAD By similarityBy similarity

GO - Molecular functioni

  1. aldehyde dehydrogenase (NAD) activity Source: UniProtKB
Complete GO annotation...

GO - Biological processi

  1. cellular aldehyde metabolic process Source: UniProtKB
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

NAD

Names & Taxonomyi

Protein namesi
Recommended name:
Aldehyde dehydrogenase family 7 member A1 (EC:1.2.1.3)
Alternative name(s):
Antiquitin-1
Matured fruit 60 kDa protein
Short name:
MF-60
OrganismiMalus domestica (Apple) (Pyrus malus)
Taxonomic identifieri3750 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsRosalesRosaceaeMaloideaeMaleaeMalus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11Removed1 Publication
Chaini2 – 508507Aldehyde dehydrogenase family 7 member A1
PRO_0000056497Add
BLAST

Expressioni

Developmental stagei

Expressed in developing fruit during the enlargement stage.1 Publication

Inductioni

By osmotic pressure changes Reviewed prediction.1 Publication

Interactioni

Subunit structurei

Homotetramer By similarity.By similarity

Structurei

3D structure databases

ProteinModelPortaliQ9ZPB7.
SMRiQ9ZPB7. Positions 5-507.

Family & Domainsi

Sequence similaritiesi

Family and domain databases

Gene3Di3.40.309.10. 1 hit.
3.40.605.10. 1 hit.
InterProiIPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR029510. Ald_DH_CS_GLU.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
[Graphical view]
PfamiPF00171. Aldedh. 1 hit.
[Graphical view]
SUPFAMiSSF53720. SSF53720. 1 hit.
PROSITEiPS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9ZPB7-1 [UniParc]FASTAAdd to Basket

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MGFAKKEHEF LSAIGLAPEN PGGFINGKWK ASGPVISTVS PSNNQEIAKV    50
TEVSMEEYEE GLRSCNDAAK TWKSLPAPKR GEIVRQIGDA LREKLQHLGK 100
LVSLEMGKIL AEGIGEVQEV IYMCDFAVGL SRQLNGSIIP SERPDHMMFE 150
VWNPLGIVGV ITAFNFPCAV LGWNACIALV CGNCVVWKGA PTTPLVTIAV 200
TKLIAEVLEK NNLPAAIFTA FCGGAEIGEA IAKDTRIPLV SFTGSSKVGA 250
KVQQIVTERF GKCLLELSGN NALIVMDDAD VGLAVRSIFF AAVGTAGQRC 300
TTCRRLYLHE SIYQNVLDKL VGLYNQVKIG DPLEEGTLVG PVHTKASREN 350
FEKGISTIKS QGGKILTGGS VIESDGNFVQ PTIVEIASNA SVVKEELFGP 400
VLYVMKFKTL EEAIALNNSV PQGLSSSIFT SKPNTIFKWI GPHGSDCGIV 450
NVNIPTNGAE IGGAFGGEKA TGGGREAGSD SWKQYMRRST CTINYGTELP 500
LAQGINFG 508
Length:508
Mass (Da):54,244
Last modified:January 23, 2007 - v3
Checksum:iFCE5487F10DEDABA
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
D88434 mRNA. Translation: BAA75633.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
D88434 mRNA. Translation: BAA75633.1 .

3D structure databases

ProteinModelPortali Q9ZPB7.
SMRi Q9ZPB7. Positions 5-507.
ModBasei Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

Gene3Di 3.40.309.10. 1 hit.
3.40.605.10. 1 hit.
InterProi IPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR029510. Ald_DH_CS_GLU.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
[Graphical view ]
Pfami PF00171. Aldedh. 1 hit.
[Graphical view ]
SUPFAMi SSF53720. SSF53720. 1 hit.
PROSITEi PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Identification and cDNA cloning of a protein abundantly expressed during apple fruit development."
    Yamada K., Mori H., Yamaki S.
    Plant Cell Physiol. 40:198-204(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA], PROTEIN SEQUENCE OF 2-31 AND 386-404, INDUCTION.
    Strain: cv. Fuji.
    Tissue: Fruit.

Entry informationi

Entry nameiAL7A1_MALDO
AccessioniPrimary (citable) accession number: Q9ZPB7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 15, 2002
Last sequence update: January 23, 2007
Last modified: July 9, 2014
This is version 73 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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