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Q9ZPB7

- AL7A1_MALDO

UniProt

Q9ZPB7 - AL7A1_MALDO

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Protein

Aldehyde dehydrogenase family 7 member A1

Gene
N/A
Organism
Malus domestica (Apple) (Pyrus malus)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli

Functioni

May play a role in fruit development.1 Publication

Catalytic activityi

An aldehyde + NAD+ + H2O = a carboxylate + NADH.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sitei165 – 1651Transition state stabilizerBy similarity
Active sitei266 – 2661Proton acceptorPROSITE-ProRule annotation
Active sitei300 – 3001NucleophilePROSITE-ProRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi244 – 2496NADBy similarity

GO - Molecular functioni

  1. aldehyde dehydrogenase (NAD) activity Source: UniProtKB

GO - Biological processi

  1. cellular aldehyde metabolic process Source: UniProtKB
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

NAD

Names & Taxonomyi

Protein namesi
Recommended name:
Aldehyde dehydrogenase family 7 member A1 (EC:1.2.1.3)
Alternative name(s):
Antiquitin-1
Matured fruit 60 kDa protein
Short name:
MF-60
OrganismiMalus domestica (Apple) (Pyrus malus)Imported
Taxonomic identifieri3750 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsRosalesRosaceaeMaloideaeMaleaeMalus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11Removed1 Publication
Chaini2 – 508507Aldehyde dehydrogenase family 7 member A1PRO_0000056497Add
BLAST

Expressioni

Developmental stagei

Expressed in developing fruit during the enlargement stage.1 Publication

Inductioni

By osmotic pressure changes.1 PublicationCurated

Interactioni

Subunit structurei

Homotetramer.By similarity

Structurei

3D structure databases

ProteinModelPortaliQ9ZPB7.
SMRiQ9ZPB7. Positions 5-507.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the aldehyde dehydrogenase family.Curated

Family and domain databases

Gene3Di3.40.309.10. 1 hit.
3.40.605.10. 1 hit.
InterProiIPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR029510. Ald_DH_CS_GLU.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
[Graphical view]
PfamiPF00171. Aldedh. 1 hit.
[Graphical view]
SUPFAMiSSF53720. SSF53720. 1 hit.
PROSITEiPS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9ZPB7 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MGFAKKEHEF LSAIGLAPEN PGGFINGKWK ASGPVISTVS PSNNQEIAKV
60 70 80 90 100
TEVSMEEYEE GLRSCNDAAK TWKSLPAPKR GEIVRQIGDA LREKLQHLGK
110 120 130 140 150
LVSLEMGKIL AEGIGEVQEV IYMCDFAVGL SRQLNGSIIP SERPDHMMFE
160 170 180 190 200
VWNPLGIVGV ITAFNFPCAV LGWNACIALV CGNCVVWKGA PTTPLVTIAV
210 220 230 240 250
TKLIAEVLEK NNLPAAIFTA FCGGAEIGEA IAKDTRIPLV SFTGSSKVGA
260 270 280 290 300
KVQQIVTERF GKCLLELSGN NALIVMDDAD VGLAVRSIFF AAVGTAGQRC
310 320 330 340 350
TTCRRLYLHE SIYQNVLDKL VGLYNQVKIG DPLEEGTLVG PVHTKASREN
360 370 380 390 400
FEKGISTIKS QGGKILTGGS VIESDGNFVQ PTIVEIASNA SVVKEELFGP
410 420 430 440 450
VLYVMKFKTL EEAIALNNSV PQGLSSSIFT SKPNTIFKWI GPHGSDCGIV
460 470 480 490 500
NVNIPTNGAE IGGAFGGEKA TGGGREAGSD SWKQYMRRST CTINYGTELP

LAQGINFG
Length:508
Mass (Da):54,244
Last modified:January 23, 2007 - v3
Checksum:iFCE5487F10DEDABA
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
D88434 mRNA. Translation: BAA75633.1.
RefSeqiNP_001281025.1. NM_001294096.1.
UniGeneiMdo.2975.

Genome annotation databases

GeneIDi103400922.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
D88434 mRNA. Translation: BAA75633.1 .
RefSeqi NP_001281025.1. NM_001294096.1.
UniGenei Mdo.2975.

3D structure databases

ProteinModelPortali Q9ZPB7.
SMRi Q9ZPB7. Positions 5-507.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 103400922.

Family and domain databases

Gene3Di 3.40.309.10. 1 hit.
3.40.605.10. 1 hit.
InterProi IPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR029510. Ald_DH_CS_GLU.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
[Graphical view ]
Pfami PF00171. Aldedh. 1 hit.
[Graphical view ]
SUPFAMi SSF53720. SSF53720. 1 hit.
PROSITEi PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Identification and cDNA cloning of a protein abundantly expressed during apple fruit development."
    Yamada K., Mori H., Yamaki S.
    Plant Cell Physiol. 40:198-204(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA], PROTEIN SEQUENCE OF 2-31 AND 386-404, INDUCTION.
    Strain: cv. Fuji.
    Tissue: Fruit.

Entry informationi

Entry nameiAL7A1_MALDO
AccessioniPrimary (citable) accession number: Q9ZPB7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 15, 2002
Last sequence update: January 23, 2007
Last modified: October 29, 2014
This is version 75 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3