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Protein

Aldehyde dehydrogenase family 7 member A1

Gene
N/A
Organism
Malus domestica (Apple) (Pyrus malus)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

May play a role in fruit development.1 Publication

Catalytic activityi

An aldehyde + NAD+ + H2O = a carboxylate + NADH.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sitei165Transition state stabilizerBy similarity1
Active sitei266Proton acceptorPROSITE-ProRule annotation1
Active sitei300NucleophilePROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi244 – 249NADBy similarity6

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
LigandNAD

Names & Taxonomyi

Protein namesi
Recommended name:
Aldehyde dehydrogenase family 7 member A1 (EC:1.2.1.3)
Alternative name(s):
Antiquitin-1
Matured fruit 60 kDa protein
Short name:
MF-60
OrganismiMalus domestica (Apple) (Pyrus malus)Imported
Taxonomic identifieri3750 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsRosalesRosaceaeAmygdaloideaeMaleaeMalus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemoved1 Publication
ChainiPRO_00000564972 – 508Aldehyde dehydrogenase family 7 member A1Add BLAST507

Proteomic databases

PRIDEiQ9ZPB7

Expressioni

Developmental stagei

Expressed in developing fruit during the enlargement stage.1 Publication

Inductioni

By osmotic pressure changes.1 PublicationCurated

Interactioni

Subunit structurei

Homotetramer.By similarity

Structurei

3D structure databases

ProteinModelPortaliQ9ZPB7
SMRiQ9ZPB7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the aldehyde dehydrogenase family.Curated

Phylogenomic databases

KOiK14085

Family and domain databases

Gene3Di3.40.309.10, 1 hit
3.40.605.10, 2 hits
InterProiView protein in InterPro
IPR016161 Ald_DH/histidinol_DH
IPR016163 Ald_DH_C
IPR029510 Ald_DH_CS_GLU
IPR016162 Ald_DH_N
IPR015590 Aldehyde_DH_dom
PfamiView protein in Pfam
PF00171 Aldedh, 1 hit
SUPFAMiSSF53720 SSF53720, 1 hit
PROSITEiView protein in PROSITE
PS00687 ALDEHYDE_DEHYDR_GLU, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9ZPB7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGFAKKEHEF LSAIGLAPEN PGGFINGKWK ASGPVISTVS PSNNQEIAKV
60 70 80 90 100
TEVSMEEYEE GLRSCNDAAK TWKSLPAPKR GEIVRQIGDA LREKLQHLGK
110 120 130 140 150
LVSLEMGKIL AEGIGEVQEV IYMCDFAVGL SRQLNGSIIP SERPDHMMFE
160 170 180 190 200
VWNPLGIVGV ITAFNFPCAV LGWNACIALV CGNCVVWKGA PTTPLVTIAV
210 220 230 240 250
TKLIAEVLEK NNLPAAIFTA FCGGAEIGEA IAKDTRIPLV SFTGSSKVGA
260 270 280 290 300
KVQQIVTERF GKCLLELSGN NALIVMDDAD VGLAVRSIFF AAVGTAGQRC
310 320 330 340 350
TTCRRLYLHE SIYQNVLDKL VGLYNQVKIG DPLEEGTLVG PVHTKASREN
360 370 380 390 400
FEKGISTIKS QGGKILTGGS VIESDGNFVQ PTIVEIASNA SVVKEELFGP
410 420 430 440 450
VLYVMKFKTL EEAIALNNSV PQGLSSSIFT SKPNTIFKWI GPHGSDCGIV
460 470 480 490 500
NVNIPTNGAE IGGAFGGEKA TGGGREAGSD SWKQYMRRST CTINYGTELP

LAQGINFG
Length:508
Mass (Da):54,244
Last modified:January 23, 2007 - v3
Checksum:iFCE5487F10DEDABA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D88434 mRNA Translation: BAA75633.1
RefSeqiNP_001281025.1, NM_001294096.1
UniGeneiMdo.2975

Genome annotation databases

GeneIDi103400922
KEGGimdm:103400922

Similar proteinsi

Entry informationi

Entry nameiAL7A1_MALDO
AccessioniPrimary (citable) accession number: Q9ZPB7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 15, 2002
Last sequence update: January 23, 2007
Last modified: May 23, 2018
This is version 83 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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