Q9ZNJ9 (MSRB_CLOHI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Peptide methionine sulfoxide reductase MsrB
EC=1.8.4.12

Alternative name(s):
Peptide-methionine (R)-S-oxide reductase

Gene names

Name:

msrB

Organism

Clostridium histolyticum

Taxonomic identifier

1498 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium

Protein attributes

Sequence length	159 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (R)-S-oxide + thioredoxin. HAMAP-Rule MF_01400
Sequence similarities	Belongs to the MsrB Met sulfoxide reductase family.

Ontologies

Keywords
Molecular function	Oxidoreductase
Gene Ontology (GO)
Molecular_function	peptide-methionine (R)-S-oxide reductase activity Inferred from electronic annotation. Source: EC peptide-methionine (S)-S-oxide reductase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 159	159	Peptide methionine sulfoxide reductase MsrB HAMAP-Rule MF_01400		PRO_0000140268
Sites
	Active site	126	1	Nucleophile By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q9ZNJ9 [UniParc]. Last modified May 1, 1999. Version 1. Checksum: FF50ACEEA1871231	FASTA	159	18,531
	10 20 30 40 50 60 MNHKKEKEYK KLDTEKLKEN LTELQYNVTQ RNATEKPFLN KYDKHFEDGI YVDIVSGEPL 70 80 90 100 110 120 FLSIDKFNSG CGWPAFSKPI SRKYIKERAD FSHGMSRIEV RSKNADSHLG HVFNDGPIEN 130 140 150 GGMRYCINSA SLKFIAKDKL KEEGYEEFLP LFEKDKQEL

References

[1]

"Gene duplication and multiplicity of collagenases in Clostridium histolyticum." Matsushita O., Jung C.-M., Katayama S., Minami J., Takahashi Y., Okabe A. J. Bacteriol. 181:923-933(1999) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 19401 / DSM 2158 / JCM 1403 / NCIB 503.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AB014075 Genomic DNA. Translation: BAA34541.1.
PIR	T44354.
3D structure databases
ProteinModelPortal	Q9ZNJ9.
SMR	Q9ZNJ9. Positions 15-154.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
Gene3D	2.170.150.20. 1 hit.
HAMAP	MF_01400. MsrB.
InterPro	IPR002579. Met_Sox_Rdtase_MsrB. IPR011057. Mss4-like. [Graphical view]
Pfam	PF01641. SelR. 1 hit. [Graphical view]
SUPFAM	SSF51316. Mss4_like. 1 hit.
TIGRFAMs	TIGR00357. TIGR00357. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MSRB_CLOHI

Accession

Primary (citable) accession number: Q9ZNJ9

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 6, 2003
Last sequence update:	May 1, 1999
Last modified:	April 3, 2013
This is version 59 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program