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Q9ZNJ9 (MSRB_CLOHI) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 63. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Peptide methionine sulfoxide reductase MsrB

EC=1.8.4.12
Alternative name(s):
Peptide-methionine (R)-S-oxide reductase
Gene names
Name:msrB
OrganismClostridium histolyticum
Taxonomic identifier1498 [NCBI]
Taxonomic lineageBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium

Protein attributes

Sequence length159 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (R)-S-oxide + thioredoxin. HAMAP-Rule MF_01400

Sequence similarities

Belongs to the MsrB Met sulfoxide reductase family.

Ontologies

Keywords
   Molecular functionOxidoreductase
Gene Ontology (GO)
   Biological_processprotein repair

Inferred from electronic annotation. Source: InterPro

response to oxidative stress

Inferred from electronic annotation. Source: InterPro

   Molecular_functionpeptide-methionine (R)-S-oxide reductase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 159159Peptide methionine sulfoxide reductase MsrB HAMAP-Rule MF_01400
PRO_0000140268

Sites

Active site1261Nucleophile By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9ZNJ9 [UniParc].

Last modified May 1, 1999. Version 1.
Checksum: FF50ACEEA1871231

FASTA15918,531
        10         20         30         40         50         60 
MNHKKEKEYK KLDTEKLKEN LTELQYNVTQ RNATEKPFLN KYDKHFEDGI YVDIVSGEPL 

        70         80         90        100        110        120 
FLSIDKFNSG CGWPAFSKPI SRKYIKERAD FSHGMSRIEV RSKNADSHLG HVFNDGPIEN 

       130        140        150 
GGMRYCINSA SLKFIAKDKL KEEGYEEFLP LFEKDKQEL 

« Hide

References

[1]"Gene duplication and multiplicity of collagenases in Clostridium histolyticum."
Matsushita O., Jung C.-M., Katayama S., Minami J., Takahashi Y., Okabe A.
J. Bacteriol. 181:923-933(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 19401 / DSM 2158 / JCM 1403 / NCIB 503.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AB014075 Genomic DNA. Translation: BAA34541.1.
PIRT44354.

3D structure databases

ProteinModelPortalQ9ZNJ9.
SMRQ9ZNJ9. Positions 15-154.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D2.170.150.20. 1 hit.
HAMAPMF_01400. MsrB.
InterProIPR028427. Met_Sox_Rdtase.
IPR002579. Met_Sox_Rdtase_MsrB.
IPR011057. Mss4-like.
[Graphical view]
PANTHERPTHR10173. PTHR10173. 1 hit.
PfamPF01641. SelR. 1 hit.
[Graphical view]
SUPFAMSSF51316. SSF51316. 1 hit.
TIGRFAMsTIGR00357. TIGR00357. 1 hit.
ProtoNetSearch...

Entry information

Entry nameMSRB_CLOHI
AccessionPrimary (citable) accession number: Q9ZNJ9
Entry history
Integrated into UniProtKB/Swiss-Prot: June 6, 2003
Last sequence update: May 1, 1999
Last modified: February 19, 2014
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families