Q9ZNJ8 (DCD_CLOHI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Deoxycytidine triphosphate deaminase
Short name=dCTP deaminase
EC=3.5.4.13

Gene names

Name:

dcd

Organism

Clostridium histolyticum

Taxonomic identifier

1498 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium

Protein attributes

Sequence length	172 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	dCTP + H2O = dUTP + NH3. HAMAP-Rule MF_00146
Pathway	Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP-Rule MF_00146
Sequence similarities	Belongs to the dCTP deaminase family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Hydrolase
Gene Ontology (GO)
Biological_process	dUMP biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway dUTP biosynthetic process Inferred from electronic annotation. Source: InterPro pyrimidine ribonucleotide biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular_function	dCTP deaminase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 172	172	Deoxycytidine triphosphate deaminase HAMAP-Rule MF_00146		PRO_0000155980

Sequences

	Sequence		Length	Mass (Da)
	Q9ZNJ8 [UniParc]. Last modified May 1, 1999. Version 1. Checksum: 520A07EF3ED0C7E3	FASTA	172	19,919
	10 20 30 40 50 60 MILSGKEIKN RLNKDIFIEP FSDNQLNPNS YNLRLHNELL VYENNVLDMK KENKAKKITI 70 80 90 100 110 120 PEEGLLLEPG KLYLGRTIEH TRTEKLVPML EGRSSVGRLG LFIHITAGFG DIGFSGFWTL 130 140 150 160 170 EIFCVQPIRI YPNIEICQIY YHNIEGEYEK YTSGKYQNNT GVQPSLLFKD FE

References

[1]

"Gene duplication and multiplicity of collagenases in Clostridium histolyticum." Matsushita O., Jung C.-M., Katayama S., Minami J., Takahashi Y., Okabe A. J. Bacteriol. 181:923-933(1999) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 19401 / DSM 2158 / JCM 1403 / NCIB 503.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AB014075 Genomic DNA. Translation: BAA34543.1.
PIR	T44356.
3D structure databases
ProteinModelPortal	Q9ZNJ8.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Enzyme and pathway databases
UniPathway	UPA00610; UER00665.
Family and domain databases
HAMAP	MF_00146. dCTP_deaminase.
InterPro	IPR011962. dCTP_deam. [Graphical view]
TIGRFAMs	TIGR02274. dCTP_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DCD_CLOHI

Accession

Primary (citable) accession number: Q9ZNJ8

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 1, 2000
Last sequence update:	May 1, 1999
Last modified:	April 3, 2013
This is version 50 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program