Reviewed, UniProtKB/Swiss-Prot Q9ZNB7 (ALGL_HALMR)

Names and origin

Protein names

Recommended name:
    Alginate lyase
    EC=4.2.2.3
Alternative name(s):
    Poly(beta-D-mannuronate) lyase
    Poly(mana) alginate lyase

Gene names

Name:	algL
Synonyms:	alg

Organism

Halomonas marina (Deleya marina)

Taxonomic identifier

28258 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Oceanospirillales › Halomonadaceae › Cobetia

Protein attributes

Sequence length	374 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Depolymerizes alginate by cleaving the beta-1,4 glycosidic bond By similarity.
Catalytic activity	Eliminative cleavage of polysaccharides containing beta-D-mannuronate residues to give oligosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enopyranuronosyl groups at their ends. HAMAP MF_00557
Subcellular location	Periplasm By similarity.
Sequence similarities	Belongs to the polysaccharide lyase 5 family.

Ontologies

Keywords
Cellular component	Periplasm
Domain	Signal
Molecular function	Lyase
Gene Ontology (GO)
Biological process	alginic acid catabolic process Inferred from electronic annotation. Source: HAMAP
Cellular component	periplasmic space Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	poly(beta-D-mannuronate) lyase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 26	26	Potential
	Chain	27 – 374	348	Alginate lyase HAMAP MF_00557		PRO_0000024917

Sequences

	Sequence		Length	Mass (Da)
	Q9ZNB7-1 [UniParc]. Last modified May 1, 1999. Version 1. Checksum: 416616B1D8A2E0FA	FASTA	374	42,219
	10 20 30 40 50 60 MRNPKLKNLL APTLLSLAMF AGATQAAAPL RPPQGYFAPV DKFKTGDKSD GCDAMPAPYT 70 80 90 100 110 120 GPLQFRSKYE GSDKARATLN VQSEKAFRDT TKDITTLERG TAKRVMQFMR DGRPEQLECT 130 140 150 160 170 180 LNWLTAWAKA DALMSKDFNH TGKSMRKWAL GSMASSYIRL KFSDSHPLAQ HQQEAQLIEA 190 200 210 220 230 240 WFSKMADQVV SDWDNLPLEK TNNHSYWAAW SVMATAVATN RRDLFDWAVK EYKVGVNQVD 250 260 270 280 290 300 ADGFLPNELK RQQRALAYHN YALPPLAMIA SFAQINGVDL RQENNGALKR LGDRVLAGVK 310 320 330 340 350 360 DPDEFEEKNG KKQDMTDLKE DMKFAWLEPF CTLYTCAPDV IEKKRDMQPF KTFRLGGDLT 370 KVYDPSHEKG NKGS

References

[1]	"Alginate lyase gene from Deleya marina." Kraiwattanapong J., Ooi T., Kinoshita S. Submitted (OCT-1998) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: N-1.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AB018795 Genomic DNA. Translation: BAA33966.1.
3D structure databases
ModBase	Search...
Protein family/group databases
CAZy	PL5. Polysaccharide Lyase Family 5.
Enzyme and pathway databases
BRENDA	4.2.2.3. 275445.
Family and domain databases
HAMAP	MF_00557. [Tree]
InterPro	IPR008397. Alginate_lyase. [Graphical view]
Gene3D	G3DSA:1.50.10.110. Alginate_lyase. 1 hit.
Pfam	PF05426. Alginate_lyase. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ALGL_HALMR

Accession

Primary (citable) accession number: Q9ZNB7

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 27, 2002
Last sequence update:	May 1, 1999
Last modified:	June 16, 2009
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)