Reviewed, UniProtKB/Swiss-Prot Q9ZN99 (CATA_DESVM)

Names and origin

Protein names

Recommended name:
    Catalase
    EC=1.11.1.6

Gene names

Name:	katA
Synonyms:	kat

Organism

Desulfovibrio vulgaris (strain Miyazaki)

Taxonomic identifier

883 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Deltaproteobacteria › Desulfovibrionales › Desulfovibrionaceae › Desulfovibrio

Protein attributes

Sequence length	479 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide.
Catalytic activity	2 H(2)O(2) = O(2) + 2 H(2)O.
Cofactor	Heme group.
Sequence similarities	Belongs to the catalase family.

Ontologies

Keywords
Biological process	Hydrogen peroxide
Ligand	Heme Iron Metal-binding
Molecular function	Oxidoreductase Peroxidase
Gene Ontology (GO)
Biological process	hydrogen peroxide catabolic process Inferred from electronic annotation. Source: UniProtKB-KW oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	iron ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 479	479	Catalase		PRO_0000084985
Sites
	Active site	54	1	By similarity
	Active site	127	1	By similarity
	Metal binding	337	1	Iron (heme axial ligand) By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q9ZN99-1 [UniParc]. Last modified May 1, 1999. Version 1. Checksum: 4CD97480AB6FD475	FASTA	479	54,549
	10 20 30 40 50 60 MTKHKLTTNA GAPVPDNQNA MTAGPRGPML LQDVWFLEKL AHFDREVIPE RRMHAKGSGA 70 80 90 100 110 120 YGTFTVTHDI TSYTKAALFS KIGKKTDLFV RFSTVAGERG AATAERDIRG FAIKFYTEQG 130 140 150 160 170 180 NWDLVGNNTP VFFLRDPLKF PDLNHAVKRD PRTNMRSAKN NWDFWTSLPE ALHQVTVVMS 190 200 210 220 230 240 DRGIPASYRH MHGFGSHTFS FISPDNQRYW VKFHLRTQQG IKNLTDAEAE AIVARDRESH 250 260 270 280 290 300 QRDLYDSIER GDFPRWTMYV QVMPEKDAEK LPYHPFDLTK VWFHKDCPLI EVGVLELNRN 310 320 330 340 350 360 PENYFAEVEQ AAFNPANVVP GISFSPDKML QGRLFSYGDA HRYRLGVNHH LIPVNAARCP 370 380 390 400 410 420 VHSYHRDGAM RVDGNHGSTL AYEPNSYGEW QEQPDFAEPP LAIRGDAAHW NFREDADYYD 430 440 450 460 470 QPGRLFRLMT PQQQDELFQN TARAMGDAPE EIKRRHVGNC AKADPAYGAG VARALGLKM

References

[1]	"Catalase from strictly anaerobic bacteria, Desulfovibrio vulgaris (Miyazaki F)." Kitamura M., Kojima S., Akutsu H., Kumagai I., Nakaya T. Submitted (NOV-1998) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AB020341 Genomic DNA. Translation: BAA34670.1.
3D structure databases
HSSP	HSSP built from PDB template 1M85 based on UniProtKB P42321.
SMR	Q9ZN99. Positions 5-479.
ModBase	Search...
Family and domain databases
InterPro	IPR002226. Catalase. IPR011614. Catalase_N. [Graphical view]
Gene3D	G3DSA:2.40.180.10. Catalase_N. 1 hit.
PANTHER	PTHR11465. Catalase. 1 hit.
Pfam	PF00199. Catalase. 1 hit. [Graphical view]
PRINTS	PR00067. CATALASE.
ProDom	PD000510. Catalase. 1 hit. [Graphical view] [Entries sharing at least one domain]
PROSITE	PS00437. CATALASE_1. 1 hit. PS00438. CATALASE_2. 1 hit. PS51402. CATALASE_3. 1 hit. [Graphical view]
BLOCKS	Search...
ProtoNet	Search...

Entry information

Entry name

CATA_DESVM

Accession

Primary (citable) accession number: Q9ZN99

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	May 1, 1999
Last modified:	November 4, 2008
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)