Q9ZN99 (CATA_DESVM) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Catalase
EC=1.11.1.6

Gene names

Name:	katA
Synonyms:	kat
Ordered Locus Names:	DvMF_1242

Organism

Desulfovibrio vulgaris (strain Miyazaki F / DSM 19637) [Complete proteome] [HAMAP]

Taxonomic identifier

883 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Deltaproteobacteria › Desulfovibrionales › Desulfovibrionaceae › Desulfovibrio

Protein attributes

Sequence length	480 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide.
Catalytic activity	2 H2O2 = O2 + 2 H2O.
Cofactor	Heme group.
Sequence similarities	Belongs to the catalase family.

Ontologies

Keywords
Biological process	Hydrogen peroxide
Ligand	Heme Iron Metal-binding
Molecular function	Oxidoreductase Peroxidase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	hydrogen peroxide catabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	catalase activity Inferred from electronic annotation. Source: EC heme binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 480	480	Catalase		PRO_0000084985
Sites
	Active site	54	1	By similarity
	Active site	127	1	By similarity
	Metal binding	337	1	Iron (heme axial ligand) By similarity
Experimental info
	Sequence conflict	103	1	D → T in BAA34670. Ref.1
	Sequence conflict	416	1	Missing in BAA34670. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	Q9ZN99 [UniParc]. Last modified April 14, 2009. Version 2. Checksum: EAE7540616B77AE4	FASTA	480	54,678
	10 20 30 40 50 60 MTKHKLTTNA GAPVPDNQNA MTAGPRGPML LQDVWFLEKL AHFDREVIPE RRMHAKGSGA 70 80 90 100 110 120 YGTFTVTHDI TSYTKAALFS KIGKKTDLFV RFSTVAGERG AADAERDIRG FAIKFYTEQG 130 140 150 160 170 180 NWDLVGNNTP VFFLRDPLKF PDLNHAVKRD PRTNMRSAKN NWDFWTSLPE ALHQVTVVMS 190 200 210 220 230 240 DRGIPASYRH MHGFGSHTFS FISPDNQRYW VKFHLRTQQG IKNLTDAEAE AIVARDRESH 250 260 270 280 290 300 QRDLYDSIER GDFPRWTMYV QVMPEKDAEK LPYHPFDLTK VWFHKDCPLI EVGVLELNRN 310 320 330 340 350 360 PENYFAEVEQ AAFNPANVVP GISFSPDKML QGRLFSYGDA HRYRLGVNHH LIPVNAARCP 370 380 390 400 410 420 VHSYHRDGAM RVDGNHGSTL AYEPNSYGEW QEQPDFAEPP LAIRGDAAHW NFREDDADYY 430 440 450 460 470 480 DQPGRLFRLM TPQQQDELFQ NTARAMGDAP EEIKRRHVGN CAKADPAYGA GVARALGLKM

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Catalase from strictly anaerobic bacteria, Desulfovibrio vulgaris (Miyazaki F)." Kitamura M., Kojima S., Akutsu H., Kumagai I., Nakaya T. Submitted (NOV-1998) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"Complete sequence of Desulfovibrio vulgaris str. 'Miyazaki F'." Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Hazen T.C., Richardson P. Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Miyazaki F / DSM 19637.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AB020341 Genomic DNA. Translation: BAA34670.1. CP001197 Genomic DNA. Translation: ACL08192.1.
RefSeq	YP_002435660.1. NC_011769.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q9ZN99.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7173145.
GenomeReviews	Gene locus DvMF_1242 in contig CP001197_GR.
KEGG	dvm:DvMF_1242.
PATRIC	21772573. VBIDesVul86729_1322.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG339355.
OMA	HSYHRDG.
ProtClustDB	CLSK704268.
Family and domain databases
InterPro	IPR018028. Catalase. IPR020835. Catalase-like_dom. IPR024708. Catalase_AS. IPR024711. Catalase_clade1/3. IPR011614. Catalase_core. IPR002226. Catalase_haem_BS. IPR010582. Catalase_immune_responsive. [Graphical view]
Gene3D	G3DSA:2.40.180.10. Catalase_N. 1 hit.
KO	K03781.
PANTHER	PTHR11465. Catalase. 1 hit.
Pfam	PF00199. Catalase. 1 hit. PF06628. Catalase-rel. 1 hit. [Graphical view]
PIRSF	PIRSF038928. Catalase_clade1-3. 1 hit.
PRINTS	PR00067. CATALASE.
SMART	SM01060. Catalase. 1 hit. [Graphical view]
SUPFAM	SSF56634. Catalase_N. 1 hit.
PROSITE	PS00437. CATALASE_1. 1 hit. PS00438. CATALASE_2. 1 hit. PS51402. CATALASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CATA_DESVM

Accession

Primary (citable) accession number: Q9ZN99
Secondary accession number(s): B8DLD0

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	April 14, 2009
Last modified:	January 25, 2012
This is version 60 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program