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Q9ZN70

- PPX_PSEAE

UniProt

Q9ZN70 - PPX_PSEAE

Protein

Exopolyphosphatase

Gene

ppx

Organism
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
Status
Reviewed - Annotation score: 4 out of 5- Protein inferred from homologyi
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    • History
      Entry version 76 (01 Oct 2014)
      Sequence version 1 (01 May 1999)
      Previous versions | rss
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    Functioni

    Degradation of inorganic polyphosphates. Orthophosphate is released progressively from the ends of polyphosphate By similarity.By similarity

    Catalytic activityi

    (Polyphosphate)(n) + H2O = (polyphosphate)(n-1) + phosphate.

    Cofactori

    Magnesium.By similarity

    GO - Molecular functioni

    1. exopolyphosphatase activity Source: PseudoCAP
    2. magnesium ion binding Source: InterPro

    GO - Biological processi

    1. bacterial-type flagellum-dependent swarming motility Source: PseudoCAP
    2. bacterial-type flagellum-dependent swimming motility Source: PseudoCAP
    3. cellular response to nitrogen starvation Source: PseudoCAP
    4. cellular response to phosphate starvation Source: PseudoCAP
    5. glycolipid biosynthetic process Source: PseudoCAP
    6. pathogenesis Source: PseudoCAP
    7. polyphosphate catabolic process Source: InterPro
    8. quorum sensing Source: PseudoCAP
    9. single-species biofilm formation Source: PseudoCAP

    Keywords - Molecular functioni

    Hydrolase

    Keywords - Ligandi

    Magnesium

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Exopolyphosphatase (EC:3.6.1.11)
    Short name:
    ExopolyPase
    Alternative name(s):
    Metaphosphatase
    Gene namesi
    Name:ppx
    Ordered Locus Names:PA5241
    OrganismiPseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
    Taxonomic identifieri208964 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
    ProteomesiUP000002438: Chromosome

    Organism-specific databases

    PseudoCAPiPA5241.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 506506ExopolyphosphatasePRO_0000194303Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi208964.PA5241.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9ZN70.
    SMRiQ9ZN70. Positions 18-505.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GppA/Ppx family.Curated

    Phylogenomic databases

    eggNOGiCOG0248.
    HOGENOMiHOG000258672.
    KOiK01524.
    OMAiENNKLLH.
    OrthoDBiEOG6M6JN6.
    PhylomeDBiQ9ZN70.

    Family and domain databases

    InterProiIPR022371. Exopolyphosphatase.
    IPR003695. Ppx_GppA.
    [Graphical view]
    PfamiPF02541. Ppx-GppA. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR03706. exo_poly_only. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q9ZN70-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDLQSMPQKP AEAFPLIAAL DLGSNSFHLC LAKANIHGEV RILERLGEKV    50
    QLAAGLDEER NLSEEATQRG LDCLRRFAQF ISGMPQGSVR VVATNALREA 100
    RNRSDFIRRA EEVLGHPVEV ISGREEARLI YLGVANSMPD SGGRRLVSDI 150
    GGGSTEFIIG QGFESELRES LQMGCVSYTQ RYFRDGKITP ARYAQAYTAA 200
    RLELMGIENS LRRLGWQQAV GASGTIRAVA LAIKAGGHGN GEISPDGLAW 250
    LKRKVLKLGD VEKLDLEGIK PDRRTIFPAG LAILEAIFDA LELEQMVHSE 300
    GALREGVLYD LVGRHQHEDV RERTISSLMQ RYHVDPEQAS RVEAKALKVL 350
    AEVGDAWELN GELHRDLLSW GARVHEIGLD IAHYHYHKHG AYLIEHSDLA 400
    GFSRQDQQML SLLVRGHRRN IPADKLAEFA EEGDKLVRLC IVLRFAILFH 450
    HIRGTQEMPS VRLKAEPKSL SVTFPEGWLE ANPLTQADFA QEAEWLKRVG 500
    YSLNVR 506
    Length:506
    Mass (Da):56,419
    Last modified:May 1, 1999 - v1
    Checksum:i91FDA10CFA04E1D4
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB022715 Genomic DNA. Translation: BAA74460.1.
    AE004091 Genomic DNA. Translation: AAG08626.1.
    PIRiH82991.
    RefSeqiNP_253928.1. NC_002516.2.

    Genome annotation databases

    EnsemblBacteriaiAAG08626; AAG08626; PA5241.
    GeneIDi877947.
    KEGGipae:PA5241.
    PATRICi19845333. VBIPseAer58763_5493.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB022715 Genomic DNA. Translation: BAA74460.1 .
    AE004091 Genomic DNA. Translation: AAG08626.1 .
    PIRi H82991.
    RefSeqi NP_253928.1. NC_002516.2.

    3D structure databases

    ProteinModelPortali Q9ZN70.
    SMRi Q9ZN70. Positions 18-505.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 208964.PA5241.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAG08626 ; AAG08626 ; PA5241 .
    GeneIDi 877947.
    KEGGi pae:PA5241.
    PATRICi 19845333. VBIPseAer58763_5493.

    Organism-specific databases

    PseudoCAPi PA5241.

    Phylogenomic databases

    eggNOGi COG0248.
    HOGENOMi HOG000258672.
    KOi K01524.
    OMAi ENNKLLH.
    OrthoDBi EOG6M6JN6.
    PhylomeDBi Q9ZN70.

    Family and domain databases

    InterProi IPR022371. Exopolyphosphatase.
    IPR003695. Ppx_GppA.
    [Graphical view ]
    Pfami PF02541. Ppx-GppA. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR03706. exo_poly_only. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The gene for an exopolyphosphatase of Pseudomonas aeruginosa."
      Miyake T., Shiba T., Kameda A., Ihara Y., Munekata M., Ishige K., Noguchi T.
      DNA Res. 6:103-108(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228.

    Entry informationi

    Entry nameiPPX_PSEAE
    AccessioniPrimary (citable) accession number: Q9ZN70
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 27, 2001
    Last sequence update: May 1, 1999
    Last modified: October 1, 2014
    This is version 76 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3