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Q9ZML7

- CDSA_HELPJ

UniProt

Q9ZML7 - CDSA_HELPJ

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Protein

Phosphatidate cytidylyltransferase

Gene

cdsA

Organism
Helicobacter pylori (strain J99 / ATCC 700824) (Campylobacter pylori J99)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

CTP + phosphatidate = diphosphate + CDP-diacylglycerol.

Pathwayi

GO - Molecular functioni

  1. phosphatidate cytidylyltransferase activity Source: UniProtKB-EC

GO - Biological processi

  1. CDP-diacylglycerol biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Biological processi

Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism

Enzyme and pathway databases

BioCyciHPYL85963:GJB9-208-MONOMER.
UniPathwayiUPA00557; UER00614.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphatidate cytidylyltransferase (EC:2.7.7.41)
Alternative name(s):
CDP-DAG synthase
CDP-DG synthase
CDP-diacylglycerol synthase
Short name:
CDS
CDP-diglyceride pyrophosphorylase
CDP-diglyceride synthase
CTP:phosphatidate cytidylyltransferase
Gene namesi
Name:cdsA
Ordered Locus Names:jhp_0201
OrganismiHelicobacter pylori (strain J99 / ATCC 700824) (Campylobacter pylori J99)
Taxonomic identifieri85963 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter
ProteomesiUP000000804: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei16 – 3621HelicalSequence AnalysisAdd
BLAST
Transmembranei52 – 7221HelicalSequence AnalysisAdd
BLAST
Transmembranei78 – 9821HelicalSequence AnalysisAdd
BLAST
Transmembranei101 – 12121HelicalSequence AnalysisAdd
BLAST
Transmembranei125 – 14521HelicalSequence AnalysisAdd
BLAST
Transmembranei164 – 18421HelicalSequence AnalysisAdd
BLAST
Transmembranei186 – 20621HelicalSequence AnalysisAdd
BLAST
Transmembranei237 – 25721HelicalSequence AnalysisAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 266266Phosphatidate cytidylyltransferasePRO_0000090738Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi85963.jhp0201.

Family & Domainsi

Sequence similaritiesi

Belongs to the CDS family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0575.
KOiK00981.
OMAiVWHISLM.
OrthoDBiEOG6TBHJT.

Family and domain databases

InterProiIPR000374. PC_trans.
[Graphical view]
PfamiPF01148. CTP_transf_1. 1 hit.
[Graphical view]
PROSITEiPS01315. CDS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9ZML7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKEELFKEKS RYITGVVLIV VAGLILYADN LLLFWAVLGG IYAVGFFEAL
60 70 80 90 100
RLFQVKASFS LYLILVLSWV AAYFNGHPVE CALISAMVMA SVIAYQKAHH
110 120 130 140 150
SEAILPFLYP GVGFFALFGV YKDFGAVAII WLLVVVVASD VGAFFGGKLL
160 170 180 190 200
GKTPFTATSP NKTLEGALIG VVLASVLGSF VGMGKLSGGF LMALLFSFLI
210 220 230 240 250
ALMAVFGDLY ESYLKRKVGV KDSGKILPGH GGVLDRLDSM LFGALSLHVL
260
LYFLEIWKET AVFLGD
Length:266
Mass (Da):28,788
Last modified:May 1, 1999 - v1
Checksum:i99C48ED30B45AF45
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE001439 Genomic DNA. Translation: AAD05785.1.
PIRiF71961.
RefSeqiNP_222922.1. NC_000921.1.

Genome annotation databases

EnsemblBacteriaiAAD05785; AAD05785; jhp_0201.
GeneIDi889289.
KEGGihpj:jhp0201.
PATRICi20605028. VBIHelPyl98156_0226.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE001439 Genomic DNA. Translation: AAD05785.1 .
PIRi F71961.
RefSeqi NP_222922.1. NC_000921.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 85963.jhp0201.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAD05785 ; AAD05785 ; jhp_0201 .
GeneIDi 889289.
KEGGi hpj:jhp0201.
PATRICi 20605028. VBIHelPyl98156_0226.

Phylogenomic databases

eggNOGi COG0575.
KOi K00981.
OMAi VWHISLM.
OrthoDBi EOG6TBHJT.

Enzyme and pathway databases

UniPathwayi UPA00557 ; UER00614 .
BioCyci HPYL85963:GJB9-208-MONOMER.

Family and domain databases

InterProi IPR000374. PC_trans.
[Graphical view ]
Pfami PF01148. CTP_transf_1. 1 hit.
[Graphical view ]
PROSITEi PS01315. CDS. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: J99 / ATCC 700824.

Entry informationi

Entry nameiCDSA_HELPJ
AccessioniPrimary (citable) accession number: Q9ZML7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: May 1, 1999
Last modified: November 26, 2014
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3