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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Helicobacter pylori (strain J99 / ATCC 700824) (Campylobacter pylori J99)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciHPYL85963:G1G1A-328-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligase (EC:6.1.1.19)
Alternative name(s):
Arginyl-tRNA synthetase
Short name:
ArgRS
Gene namesi
Name:argS
Ordered Locus Names:jhp_0302
OrganismiHelicobacter pylori (strain J99 / ATCC 700824) (Campylobacter pylori J99)
Taxonomic identifieri85963 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter
Proteomesi
  • UP000000804 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001515661 – 541Arginine--tRNA ligaseAdd BLAST541

Interactioni

Subunit structurei

Monomer.By similarity

Protein-protein interaction databases

STRINGi85963.jhp0302

Structurei

3D structure databases

ProteinModelPortaliQ9ZMB9
SMRiQ9ZMB9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi119 – 129"HIGH" regionAdd BLAST11

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4105C75 Bacteria
COG0018 LUCA
KOiK01887
OMAiNKPLHLG
OrthoDBiPOG091H01RF

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.701 hit
3.40.50.6201 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

Q9ZMB9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHTLIKGVLE EILEAEVIIE YPKDREHGHY ATPIAFNLAK VFKKSPLAIA
60 70 80 90 100
EELALKIGSH EKTQGFFDRV VACKGYINFT LSLDFLERFT QKALELKEQF
110 120 130 140 150
GSQVKSERSQ KIFLEFVSAN PTGPLHIGHA RGAVFGDSLA KIARFLGHEV
160 170 180 190 200
LCEYYVNDMG SQIRLLGVSV WLAYKEHVLK ESVTYPEVFY KGEYIIEIAK
210 220 230 240 250
KAHNDLEPSL FKENEETIIE VLSDYAKDLM LLEIKGNLDA LDIHFDSYAS
260 270 280 290 300
EKEVFKHKDA VFDRLEKANA LYEKDSKTWL KSSLYQDESD RVLIKEDKSY
310 320 330 340 350
TYLAGDIVYH DEKFQQNYTK YINIWGADHH GYIARVKASL EFLGYDSSKL
360 370 380 390 400
EVLLAQMVRL LKDNEPYKMS KRAGNFILIK DVIDDVGKDA LRFIFLSKRL
410 420 430 440 450
DTHLEFDVNT LKKQDSSNPI YYIHYANSRI HTMLEKSPFS KEEILQTPLK
460 470 480 490 500
NLNAEEKYLL FSALSLPKAV ESSFEEYGLQ KMCEYAKTLA SEFHRFYNAG
510 520 530 540
KILDTPKAKE LLKICLMVSL SLTNAFKLLG IEIKTKISSK D
Length:541
Mass (Da):62,158
Last modified:May 1, 1999 - v1
Checksum:i81524A78BC125281
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE001439 Genomic DNA Translation: AAD05887.1
PIRiH71947
RefSeqiWP_000557128.1, NZ_CP011330.1

Genome annotation databases

EnsemblBacteriaiAAD05887; AAD05887; jhp_0302
KEGGihpj:jhp_0302
PATRICifig|85963.30.peg.711

Similar proteinsi

Entry informationi

Entry nameiSYR_HELPJ
AccessioniPrimary (citable) accession number: Q9ZMB9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: May 1, 1999
Last modified: February 28, 2018
This is version 118 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome