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Q9ZLW5

- GLNA_HELPJ

UniProt

Q9ZLW5 - GLNA_HELPJ

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Protein

Glutamine synthetase

Gene

glnA

Organism
Helicobacter pylori (strain J99 / ATCC 700824) (Campylobacter pylori J99)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine.

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. glutamate-ammonia ligase activity Source: UniProtKB-EC

GO - Biological processi

  1. glutamine biosynthetic process Source: InterPro
  2. nitrogen fixation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciHPYL85963:GJB9-473-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamine synthetase (EC:6.3.1.2)
Alternative name(s):
Glutamate--ammonia ligase
Gene namesi
Name:glnA
Ordered Locus Names:jhp_0461
OrganismiHelicobacter pylori (strain J99 / ATCC 700824) (Campylobacter pylori J99)
Taxonomic identifieri85963 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter
ProteomesiUP000000804: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 481481Glutamine synthetasePRO_0000153240Add
BLAST

Interactioni

Subunit structurei

Oligomer of 12 subunits arranged in the form of two hexagons.By similarity

Protein-protein interaction databases

STRINGi85963.jhp0461.

Structurei

3D structure databases

ProteinModelPortaliQ9ZLW5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glutamine synthetase family.Curated

Phylogenomic databases

eggNOGiCOG0174.
KOiK01915.
OMAiDMLLMPI.
OrthoDBiEOG6B360N.

Family and domain databases

Gene3Di3.10.20.70. 1 hit.
3.30.590.10. 1 hit.
InterProiIPR008147. Gln_synt_beta.
IPR014746. Gln_synth/guanido_kin_cat_dom.
IPR008146. Gln_synth_cat_dom.
IPR027303. Gln_synth_gly_rich_site.
IPR004809. Gln_synth_I.
[Graphical view]
PfamiPF00120. Gln-synt_C. 1 hit.
PF03951. Gln-synt_N. 1 hit.
[Graphical view]
SUPFAMiSSF54368. SSF54368. 1 hit.
TIGRFAMsiTIGR00653. GlnA. 1 hit.
PROSITEiPS00181. GLNA_ATP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9ZLW5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MVVRTQNSES KIKEFFEFCK ENEVEFVDFR FSDIKGTWNH IAYSFGALTH
60 70 80 90 100
DMFKEGIPFD ASSFKGWQGI EHSDMILTPD LVRYFIDPFS ADVSAVVFCD
110 120 130 140 150
VYDVYKNQPY EKCPRSIAKK ALKHLRDLGL GDVAYFGAEN EFFIFDSIKI
160 170 180 190 200
KDASNSQYYE VDSEEGEWNR DKSFENGVNF GHRPGKQGGY MPVPPTDTMM
210 220 230 240 250
DIRTEIVKVL NQVGLETFVV HHEVAQAQGE VGVKFGDLVE AADNVQKLKY
260 270 280 290 300
VVKMVAHLNG KTATFMPKPL YGDNGSGMHT HVSIWKNNEN LFGGETYKGL
310 320 330 340 350
SEFALYFLGG VLRHARGLAA FTNASTNSYK RLIPGYEAPS ILTYSASNRS
360 370 380 390 400
ASVRIPYGIS KNSARFEFRF PDSSSNPYLA FGAILMAGID GIKNKMDPGE
410 420 430 440 450
AMDINLFKLT LDEIREKGIK QMPHTLRRSL EEMLADKQYL KEGQVFSEEF
460 470 480
IQAYQSLKFH SEVFPWESKP HPFEFITTYS C
Length:481
Mass (Da):54,566
Last modified:May 1, 1999 - v1
Checksum:i1F7233D870B27299
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE001439 Genomic DNA. Translation: AAD06042.1.
PIRiB71929.
RefSeqiNP_223179.1. NC_000921.1.

Genome annotation databases

EnsemblBacteriaiAAD06042; AAD06042; jhp_0461.
GeneIDi889208.
KEGGihpj:jhp0461.
PATRICi20605602. VBIHelPyl98156_0507.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE001439 Genomic DNA. Translation: AAD06042.1 .
PIRi B71929.
RefSeqi NP_223179.1. NC_000921.1.

3D structure databases

ProteinModelPortali Q9ZLW5.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 85963.jhp0461.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAD06042 ; AAD06042 ; jhp_0461 .
GeneIDi 889208.
KEGGi hpj:jhp0461.
PATRICi 20605602. VBIHelPyl98156_0507.

Phylogenomic databases

eggNOGi COG0174.
KOi K01915.
OMAi DMLLMPI.
OrthoDBi EOG6B360N.

Enzyme and pathway databases

BioCyci HPYL85963:GJB9-473-MONOMER.

Family and domain databases

Gene3Di 3.10.20.70. 1 hit.
3.30.590.10. 1 hit.
InterProi IPR008147. Gln_synt_beta.
IPR014746. Gln_synth/guanido_kin_cat_dom.
IPR008146. Gln_synth_cat_dom.
IPR027303. Gln_synth_gly_rich_site.
IPR004809. Gln_synth_I.
[Graphical view ]
Pfami PF00120. Gln-synt_C. 1 hit.
PF03951. Gln-synt_N. 1 hit.
[Graphical view ]
SUPFAMi SSF54368. SSF54368. 1 hit.
TIGRFAMsi TIGR00653. GlnA. 1 hit.
PROSITEi PS00181. GLNA_ATP. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: J99 / ATCC 700824.

Entry informationi

Entry nameiGLNA_HELPJ
AccessioniPrimary (citable) accession number: Q9ZLW5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: May 1, 1999
Last modified: October 29, 2014
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3