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Q9ZLE0

- KDGL_HELPJ

UniProt

Q9ZLE0 - KDGL_HELPJ

Protein

Diacylglycerol kinase

Gene

dgkA

Organism
Helicobacter pylori (strain J99 / ATCC 700824) (Campylobacter pylori J99)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
  1. Functioni

    Recycling of diacylglycerol produced during the turnover of membrane phospholipid.By similarity

    Catalytic activityi

    ATP + 1,2-diacyl-sn-glycerol = ADP + 1,2-diacyl-sn-glycerol 3-phosphate.

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. diacylglycerol kinase activity Source: UniProtKB-EC

    GO - Biological processi

    1. phospholipid biosynthetic process Source: UniProtKB-KW

    Keywords - Molecular functioni

    Kinase, Transferase

    Keywords - Biological processi

    Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciHPYL85963:GJB9-651-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Diacylglycerol kinase (EC:2.7.1.107)
    Short name:
    DAGK
    Alternative name(s):
    Diglyceride kinase
    Short name:
    DGK
    Gene namesi
    Name:dgkA
    Ordered Locus Names:jhp_0640
    OrganismiHelicobacter pylori (strain J99 / ATCC 700824) (Campylobacter pylori J99)
    Taxonomic identifieri85963 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter
    ProteomesiUP000000804: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell inner membrane, Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 128128Diacylglycerol kinasePRO_0000195265Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi85963.jhp0640.

    Structurei

    Topological domain

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Topological domaini1 – 3434CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini56 – 572PeriplasmicSequence Analysis
    Topological domaini79 – 10628CytoplasmicSequence AnalysisAdd
    BLAST

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei35 – 5521HelicalSequence AnalysisAdd
    BLAST
    Transmembranei58 – 7821HelicalSequence AnalysisAdd
    BLAST
    Transmembranei107 – 12721HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG0818.
    KOiK00901.
    OMAiDGLKCAW.
    OrthoDBiEOG60W7XM.

    Family and domain databases

    InterProiIPR000829. Diacylglycerol_kinase_prok.
    [Graphical view]
    PfamiPF01219. DAGK_prokar. 1 hit.
    [Graphical view]
    PROSITEiPS01069. DAGK_PROKAR. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9ZLE0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSDFKVPPKA KGFKRLFKAL FYSKDGLKCA WAEESAFRQI VILALFCIVL    50
    ASYLTKDFLE WGLLILPCFL SVVIELINSS IEKAVDFTGT EFHPLAKKAK 100
    DMASSAQLIG LIFWAFIWGR YLLTLYFN 128
    Length:128
    Mass (Da):14,598
    Last modified:May 1, 1999 - v1
    Checksum:iAC96B8630A8B1B7D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE001439 Genomic DNA. Translation: AAD06218.1.
    PIRiD71906.
    RefSeqiNP_223358.1. NC_000921.1.
    WP_001279229.1. NC_000921.1.

    Genome annotation databases

    EnsemblBacteriaiAAD06218; AAD06218; jhp_0640.
    GeneIDi890264.
    KEGGihpj:jhp0640.
    PATRICi20605991. VBIHelPyl98156_0701.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE001439 Genomic DNA. Translation: AAD06218.1 .
    PIRi D71906.
    RefSeqi NP_223358.1. NC_000921.1.
    WP_001279229.1. NC_000921.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 85963.jhp0640.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAD06218 ; AAD06218 ; jhp_0640 .
    GeneIDi 890264.
    KEGGi hpj:jhp0640.
    PATRICi 20605991. VBIHelPyl98156_0701.

    Phylogenomic databases

    eggNOGi COG0818.
    KOi K00901.
    OMAi DGLKCAW.
    OrthoDBi EOG60W7XM.

    Enzyme and pathway databases

    BioCyci HPYL85963:GJB9-651-MONOMER.

    Family and domain databases

    InterProi IPR000829. Diacylglycerol_kinase_prok.
    [Graphical view ]
    Pfami PF01219. DAGK_prokar. 1 hit.
    [Graphical view ]
    PROSITEi PS01069. DAGK_PROKAR. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: J99 / ATCC 700824.

    Entry informationi

    Entry nameiKDGL_HELPJ
    AccessioniPrimary (citable) accession number: Q9ZLE0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 1, 2000
    Last sequence update: May 1, 1999
    Last modified: October 1, 2014
    This is version 85 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3