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Q9ZL96

- TRMB_HELPJ

UniProt

Q9ZL96 - TRMB_HELPJ

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Protein

tRNA (guanine-N(7)-)-methyltransferase

Gene
trmB, jhp_0684
Organism
Helicobacter pylori (strain J99 / ATCC 700824) (Campylobacter pylori J99)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA By similarity.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + guanine(46) in tRNA = S-adenosyl-L-homocysteine + N(7)-methylguanine(46) in tRNA.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei124 – 1241S-adenosyl-L-methionine By similarity
Binding sitei149 – 1491S-adenosyl-L-methionine By similarity
Binding sitei176 – 1761S-adenosyl-L-methionine By similarity
Binding sitei232 – 2321Substrate By similarity

GO - Molecular functioni

  1. tRNA (guanine-N7-)-methyltransferase activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Biological processi

tRNA processing

Keywords - Ligandi

S-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciHPYL85963:GJB9-696-MONOMER.
UniPathwayiUPA00989.

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA (guanine-N(7)-)-methyltransferase (EC:2.1.1.33)
Alternative name(s):
tRNA (guanine(46)-N(7))-methyltransferase
tRNA(m7G46)-methyltransferase
Gene namesi
Name:trmB
Ordered Locus Names:jhp_0684
OrganismiHelicobacter pylori (strain J99 / ATCC 700824) (Campylobacter pylori J99)
Taxonomic identifieri85963 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter
ProteomesiUP000000804: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 400400tRNA (guanine-N(7)-)-methyltransferaseUniRule annotationPRO_0000171336Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi85963.jhp0684.

Structurei

3D structure databases

ProteinModelPortaliQ9ZL96.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0220.
KOiK03439.
OMAiSKYEARW.
OrthoDBiEOG6K6VBC.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_01057. tRNA_methyltr_TrmB.
InterProiIPR029063. SAM-dependent_MTases-like.
IPR003358. tRNA_(Gua-N-7)_MeTrfase.
[Graphical view]
PfamiPF02390. Methyltransf_4. 1 hit.
[Graphical view]
SUPFAMiSSF53335. SSF53335. 1 hit.
TIGRFAMsiTIGR00091. TIGR00091. 1 hit.
PROSITEiPS51625. SAM_MT_TRMB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9ZL96-1 [UniParc]FASTAAdd to Basket

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MPHFLAKLDS KPLEYPLIRG DFCFHREFLS LKHPTKSCVH ASFKNDVFLL    50
QKIRRAGDFL IKSEKATPLK REILKQALRI YSQSFEVISH NLQENSKHAS 100
QKKALDLETF EDFIQKNQAP ILIEIGFGSG RHLIELAKNN PTTTCLGIEI 150
HTPSIAQALK QIELLDLKNL HILQGDGRLV LESMPNHRCE KIFVHFPVPW 200
NEKKHRRVLS EKFLNEALRV LKPRGFLELR TDDSLCFEDS LKLALKNFQC 250
EIEIKKNAQI PVVSKYEARW NKLKKDIYDL KIYSLGLDEN PTQNHALDFS 300
FDTITIDKES VGAILKTPKI IKEGYFVHVC NIYENKGDFL VELSMGDFDW 350
PVRLFVLLAE NQVFYLNKSP LKTLNNHKAH LLLQNILSQK ELDERDHRSE 400
Length:400
Mass (Da):46,403
Last modified:May 1, 1999 - v1
Checksum:i8B92B929183D3573
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE001439 Genomic DNA. Translation: AAD06272.1.
PIRiD71900.
RefSeqiNP_223402.1. NC_000921.1.
WP_001119966.1. NC_000921.1.

Genome annotation databases

EnsemblBacteriaiAAD06272; AAD06272; jhp_0684.
GeneIDi890215.
KEGGihpj:jhp0684.
PATRICi20606087. VBIHelPyl98156_0749.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE001439 Genomic DNA. Translation: AAD06272.1 .
PIRi D71900.
RefSeqi NP_223402.1. NC_000921.1.
WP_001119966.1. NC_000921.1.

3D structure databases

ProteinModelPortali Q9ZL96.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 85963.jhp0684.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAD06272 ; AAD06272 ; jhp_0684 .
GeneIDi 890215.
KEGGi hpj:jhp0684.
PATRICi 20606087. VBIHelPyl98156_0749.

Phylogenomic databases

eggNOGi COG0220.
KOi K03439.
OMAi SKYEARW.
OrthoDBi EOG6K6VBC.

Enzyme and pathway databases

UniPathwayi UPA00989 .
BioCyci HPYL85963:GJB9-696-MONOMER.

Family and domain databases

Gene3Di 3.40.50.150. 1 hit.
HAMAPi MF_01057. tRNA_methyltr_TrmB.
InterProi IPR029063. SAM-dependent_MTases-like.
IPR003358. tRNA_(Gua-N-7)_MeTrfase.
[Graphical view ]
Pfami PF02390. Methyltransf_4. 1 hit.
[Graphical view ]
SUPFAMi SSF53335. SSF53335. 1 hit.
TIGRFAMsi TIGR00091. TIGR00091. 1 hit.
PROSITEi PS51625. SAM_MT_TRMB. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: J99 / ATCC 700824.

Entry informationi

Entry nameiTRMB_HELPJ
AccessioniPrimary (citable) accession number: Q9ZL96
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 1, 2001
Last sequence update: May 1, 1999
Last modified: September 3, 2014
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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