Q9ZL73 (FLHB_HELPJ) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Flagellar biosynthetic protein FlhB

Gene names

Name:	flhB
Ordered Locus Names:	jhp_0707

Organism

Helicobacter pylori (strain J99) (Campylobacter pylori J99) [Complete proteome] [HAMAP]

Taxonomic identifier

85963 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › delta/epsilon subdivisions › Epsilonproteobacteria › Campylobacterales › Helicobacteraceae › Helicobacter › Helicobacter pylori

Protein attributes

Sequence length	358 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin By similarity.
Subcellular location	Cell inner membrane; Multi-pass membrane protein Potential.
Sequence similarities	Belongs to the type III secretion exporter family.

Ontologies

Keywords
Biological process	Bacterial flagellum biogenesis Bacterial flagellum protein export Protein transport Transport
Cellular component	Cell inner membrane Cell membrane Membrane
Domain	Transmembrane Transmembrane helix
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	flagellum organization Inferred from electronic annotation. Source: UniProtKB-KW protein secretion Inferred from electronic annotation. Source: InterPro
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 358	358	Flagellar biosynthetic protein FlhB		PRO_0000180952
Regions
	Transmembrane	31 – 51	21	Helical; Potential
	Transmembrane	86 – 106	21	Helical; Potential
	Transmembrane	144 – 164	21	Helical; Potential
	Transmembrane	187 – 207	21	Helical; Potential
	Transmembrane	323 – 343	21	Helical; Potential

Sequences

	Sequence		Length	Mass (Da)
	Q9ZL73 [UniParc]. Last modified May 1, 1999. Version 1. Checksum: 97746E6B5CA0BD38	FASTA	358	41,132
	10 20 30 40 50 60 MAEEEKTELP SAKKIQKARE EGNVPKSMEV VGFLGLLAGL MSIFVFFIWW VDGFSEMYRH 70 80 90 100 110 120 VLKDFSLDFS KESVQELFNQ LAKDTFLLLL PVLIILMVVA FLSNVLQFGW LFAPKVIEPK 130 140 150 160 170 180 FSKINPINGV KNLFSLKKIL DGSLITLKVF LAFFLGFFIF SLFLGELNHA ALLNLQGQLL 190 200 210 220 230 240 WFKSKALWLI SSLLFLFFVL AFVDLIIKRR QYTNSLKMTK QEVKDEYKQQ EGNPEIKAKI 250 260 270 280 290 300 RQMMVKNATN KMMQEIPKSN VVVTNPTHYA VALKFDEEHP VPVVVAKGTD YLAIRIKGIA 310 320 330 340 350 REHDIEIIEN KTLARELYRD VKLNATIPEE LFEAVAIVFA QVAKLEQERQ KQKIIKPL

References

[1]

"Genomic sequence comparison of two unrelated isolates of the human gastric pathogen Helicobacter pylori." Alm R.A., Ling L.-S.L., Moir D.T., King B.L., Brown E.D., Doig P.C., Smith D.R., Noonan B., Guild B.C., deJonge B.L., Carmel G., Tummino P.J., Caruso A., Uria-Nickelsen M., Mills D.M., Ives C., Gibson R., Merberg D. , Mills S.D., Jiang Q., Taylor D.E., Vovis G.F., Trust T.J. Nature 397:176-180(1999) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: J99.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE001439 Genomic DNA. Translation: AAD06292.1.
PIR	F71897.
RefSeq	NP_223425.1. NC_000921.1.
3D structure databases
ProteinModelPortal	Q9ZL73.
ModBase	Search...
Protein-protein interaction databases
STRING	85963.jhp0707.
Protein family/group databases
MEROPS	N06.A01.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAD06292; AAD06292; jhp_0707.
GeneID	890192.
KEGG	hpj:jhp0707.
PATRIC	20606137. VBIHelPyl98156_0774.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1377.
KO	K02401.
OMA	DGFSEMY.
ProtClustDB	PRK05702.
Enzyme and pathway databases
BioCyc	HPYL85963:GJB9-719-MONOMER.
Family and domain databases
InterPro	IPR006136. T3SS_FlhB. IPR006135. T3SS_substrate_exporter. [Graphical view]
Pfam	PF01312. Bac_export_2. 1 hit. [Graphical view]
PRINTS	PR00950. TYPE3IMSPROT.
TIGRFAMs	TIGR00328. flhB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

FLHB_HELPJ

Accession

Primary (citable) accession number: Q9ZL73

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 11, 2001
Last sequence update:	May 1, 1999
Last modified:	May 1, 2013
This is version 85 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program