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Protein

Phosphate acetyltransferase

Gene

pta

Organism
Helicobacter pylori (strain J99 / ATCC 700824) (Campylobacter pylori J99)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

Acetyl-CoA + phosphate = CoA + acetyl phosphate.

Pathwayi: acetyl-CoA biosynthesis

This protein is involved in step 2 of the subpathway that synthesizes acetyl-CoA from acetate.
Proteins known to be involved in the 2 steps of the subpathway in this organism are:
  1. Acetate kinase (ackA)
  2. Phosphate acetyltransferase (pta)
This subpathway is part of the pathway acetyl-CoA biosynthesis, which is itself part of Metabolic intermediate biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes acetyl-CoA from acetate, the pathway acetyl-CoA biosynthesis and in Metabolic intermediate biosynthesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAcyltransferase, Transferase

Enzyme and pathway databases

BioCyciHPYL85963:G1G1A-899-MONOMER
UniPathwayiUPA00340; UER00459

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphate acetyltransferase (EC:2.3.1.8)
Alternative name(s):
Phosphotransacetylase
Gene namesi
Name:pta
Ordered Locus Names:jhp_0841
OrganismiHelicobacter pylori (strain J99 / ATCC 700824) (Campylobacter pylori J99)
Taxonomic identifieri85963 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter
Proteomesi
  • UP000000804 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001791311 – 519Phosphate acetyltransferaseAdd BLAST519

Proteomic databases

PRIDEiQ9ZKU4

Interactioni

Protein-protein interaction databases

STRINGi85963.jhp0841

Structurei

3D structure databases

ProteinModelPortaliQ9ZKU4
SMRiQ9ZKU4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni196 – 519Phosphate acetyltransferaseAdd BLAST324

Sequence similaritiesi

In the N-terminal section; belongs to the CobB/CobQ family.Curated
In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.Curated

Phylogenomic databases

eggNOGiENOG4105C6K Bacteria
COG0280 LUCA
COG0857 LUCA
KOiK13788
OMAiKPHFLSA
OrthoDBiPOG091H01MW

Family and domain databases

InterProiView protein in InterPro
IPR004614 P_AcTrfase
IPR002505 PTA_PTB
PfamiView protein in Pfam
PF01515 PTA_PTB, 1 hit
TIGRFAMsiTIGR00651 pta, 1 hit

Sequencei

Sequence statusi: Complete.

Q9ZKU4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQSLWIYPED TEVLGAACKS LLKALKPRYQ KIALFSPISG GCEGFGECES
60 70 80 90 100
LSSLEVHSAI DKQKALELVS TAQEELLFET ILKRYDELQS THDFVINLGY
110 120 130 140 150
APKFFLNALL DLNTILAKHL NAPVVAVAQT SLDHLKAMHS HILKKEAPFA
160 170 180 190 200
IGLFVGETLE KPHFLSASLC KQQCELEASA IENLLQTKSE IITPLAFQRS
210 220 230 240 250
LEKKAKKQIK KVVLPESEDE RILKAAHRLN LMGAVGLILL GDKEAINSQA
260 270 280 290 300
KNLNLNLENV EIINPNTSHY REEFAKSLYE LRKSKGLSEQ EAERLALDKT
310 320 330 340 350
YFATMLVHLG YAHAMVSGVN HTTAETIRPA LQIIKTKPGV SLVSSVFLMC
360 370 380 390 400
LDTQVFVFGD CAIIPNPSPK ELAEIATTSA QTAKQFNIAP KVALLSYATG
410 420 430 440 450
NSAQGEMIDK INEALTIVQK LDPQLEIDGP LQFDASIDKG VAKKKMPNSQ
460 470 480 490 500
VAGQASVFIF PDLNAGNIAY KAVQRSAKAV AIGPILQGLN KPINDLSRGA
510
LVEDIVNTVL ISAIQAQDY
Length:519
Mass (Da):56,738
Last modified:May 1, 1999 - v1
Checksum:i3E5A71FC8BBBAD37
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE001439 Genomic DNA Translation: AAD06419.1
PIRiD71881
RefSeqiWP_001191463.1, NZ_CP011330.1

Genome annotation databases

EnsemblBacteriaiAAD06419; AAD06419; jhp_0841
KEGGihpj:jhp_0841
PATRICifig|85963.30.peg.126

Similar proteinsi

Entry informationi

Entry nameiPTAS_HELPJ
AccessioniPrimary (citable) accession number: Q9ZKU4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: May 1, 1999
Last modified: May 23, 2018
This is version 107 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

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