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Protein

50S ribosomal protein L1

Gene

rplA

Organism
Helicobacter pylori (strain J99 / ATCC 700824) (Campylobacter pylori J99)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.UniRule annotation
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Repressor, Ribonucleoprotein, Ribosomal protein

Keywords - Biological processi

Translation regulation

Keywords - Ligandi

RNA-binding, rRNA-binding, tRNA-binding

Enzyme and pathway databases

BioCyciHPYL85963:GJB9-1153-MONOMER.

Protein family/group databases

TCDBi1.C.82.1.1. the pore-forming amphipathic helical peptide hp(2-20) (hp2-20) family.

Names & Taxonomyi

Protein namesi
Recommended name:
50S ribosomal protein L1UniRule annotation
Gene namesi
Name:rplAUniRule annotation
Ordered Locus Names:jhp_1124
OrganismiHelicobacter pylori (strain J99 / ATCC 700824) (Campylobacter pylori J99)
Taxonomic identifieri85963 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter
Proteomesi
  • UP000000804 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 23423450S ribosomal protein L1PRO_0000125668Add
BLAST

Interactioni

Subunit structurei

Part of the 50S ribosomal subunit.UniRule annotation

Protein-protein interaction databases

STRINGi85963.jhp1124.

Structurei

3D structure databases

ProteinModelPortaliQ9ZK21.
SMRiQ9ZK21. Positions 7-227.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein L1P family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0081. LUCA.
KOiK02863.
OMAiKIQNDKV.
OrthoDBiEOG6FBX2G.

Family and domain databases

Gene3Di3.30.190.20. 2 hits.
3.40.50.790. 1 hit.
HAMAPiMF_01318_B. Ribosomal_L1_B.
InterProiIPR005878. Ribosom_L1_bac-type.
IPR002143. Ribosomal_L1.
IPR023674. Ribosomal_L1-like.
IPR028364. Ribosomal_L1/biogenesis.
IPR016094. Ribosomal_L1_2-a/b-sand.
IPR016095. Ribosomal_L1_3-a/b-sand.
IPR023673. Ribosomal_L1_CS.
[Graphical view]
PfamiPF00687. Ribosomal_L1. 1 hit.
[Graphical view]
PIRSFiPIRSF002155. Ribosomal_L1. 1 hit.
SUPFAMiSSF56808. SSF56808. 1 hit.
TIGRFAMsiTIGR01169. rplA_bact. 1 hit.
PROSITEiPS01199. RIBOSOMAL_L1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9ZK21-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKKVFKRLE KLFSKIQNDK VYGVEHGVEV VKSLASAKFD ETVEVALRLG
60 70 80 90 100
VDPRHADQMV RGAVVLLHGT GKKVRVAVFA KDIKQDEAKN AGADVVGGDD
110 120 130 140 150
LAEEIKNGRI DFDMVIATPD MMAVVGKVGR ILGPKGLMPN PKTGTVTMDI
160 170 180 190 200
AKAVTNAKSG QVNFRVDKKG NVHAPIGKAS FPEEKIKENM LELVKTINRL
210 220 230
KPSSAKGKYI RNAALSLTMS PSVNLDAQEL MDIK
Length:234
Mass (Da):25,361
Last modified:May 1, 1999 - v1
Checksum:i14C77CFC1483A2A4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE001439 Genomic DNA. Translation: AAD06702.1.
PIRiE71846.
RefSeqiWP_001085856.1. NC_000921.1.

Genome annotation databases

EnsemblBacteriaiAAD06702; AAD06702; jhp_1124.
KEGGihpj:jhp_1124.
PATRICi20607066. VBIHelPyl98156_1221.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE001439 Genomic DNA. Translation: AAD06702.1.
PIRiE71846.
RefSeqiWP_001085856.1. NC_000921.1.

3D structure databases

ProteinModelPortaliQ9ZK21.
SMRiQ9ZK21. Positions 7-227.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi85963.jhp1124.

Protein family/group databases

TCDBi1.C.82.1.1. the pore-forming amphipathic helical peptide hp(2-20) (hp2-20) family.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAD06702; AAD06702; jhp_1124.
KEGGihpj:jhp_1124.
PATRICi20607066. VBIHelPyl98156_1221.

Phylogenomic databases

eggNOGiCOG0081. LUCA.
KOiK02863.
OMAiKIQNDKV.
OrthoDBiEOG6FBX2G.

Enzyme and pathway databases

BioCyciHPYL85963:GJB9-1153-MONOMER.

Family and domain databases

Gene3Di3.30.190.20. 2 hits.
3.40.50.790. 1 hit.
HAMAPiMF_01318_B. Ribosomal_L1_B.
InterProiIPR005878. Ribosom_L1_bac-type.
IPR002143. Ribosomal_L1.
IPR023674. Ribosomal_L1-like.
IPR028364. Ribosomal_L1/biogenesis.
IPR016094. Ribosomal_L1_2-a/b-sand.
IPR016095. Ribosomal_L1_3-a/b-sand.
IPR023673. Ribosomal_L1_CS.
[Graphical view]
PfamiPF00687. Ribosomal_L1. 1 hit.
[Graphical view]
PIRSFiPIRSF002155. Ribosomal_L1. 1 hit.
SUPFAMiSSF56808. SSF56808. 1 hit.
TIGRFAMsiTIGR01169. rplA_bact. 1 hit.
PROSITEiPS01199. RIBOSOMAL_L1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: J99 / ATCC 700824.

Entry informationi

Entry nameiRL1_HELPJ
AccessioniPrimary (citable) accession number: Q9ZK21
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: May 1, 1999
Last modified: December 9, 2015
This is version 94 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.