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Protein

50S ribosomal protein L1

Gene

rplA

Organism
Helicobacter pylori (strain J99 / ATCC 700824) (Campylobacter pylori J99)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.UniRule annotation
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRepressor, Ribonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding, tRNA-binding
Biological processTranslation regulation

Enzyme and pathway databases

BioCyciHPYL85963:G1G1A-1205-MONOMER

Protein family/group databases

TCDBi1.C.82.1.1 the pore-forming amphipathic helical peptide hp(2-20) (hp2-20) family

Names & Taxonomyi

Protein namesi
Recommended name:
50S ribosomal protein L1UniRule annotation
Gene namesi
Name:rplAUniRule annotation
Ordered Locus Names:jhp_1124
OrganismiHelicobacter pylori (strain J99 / ATCC 700824) (Campylobacter pylori J99)
Taxonomic identifieri85963 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter
Proteomesi
  • UP000000804 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001256681 – 23450S ribosomal protein L1Add BLAST234

Proteomic databases

PRIDEiQ9ZK21

Interactioni

Subunit structurei

Part of the 50S ribosomal subunit.UniRule annotation

Protein-protein interaction databases

STRINGi85963.jhp1124

Structurei

3D structure databases

ProteinModelPortaliQ9ZK21
SMRiQ9ZK21
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the universal ribosomal protein uL1 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0081 LUCA
KOiK02863
OMAiGWTDVDV
OrthoDBiPOG091H023J

Family and domain databases

CDDicd00403 Ribosomal_L1, 1 hit
Gene3Di3.40.50.790, 1 hit
HAMAPiMF_01318_B Ribosomal_L1_B, 1 hit
InterProiView protein in InterPro
IPR005878 Ribosom_L1_bac-type
IPR002143 Ribosomal_L1
IPR023674 Ribosomal_L1-like
IPR028364 Ribosomal_L1/biogenesis
IPR016095 Ribosomal_L1_3-a/b-sand
IPR023673 Ribosomal_L1_CS
PfamiView protein in Pfam
PF00687 Ribosomal_L1, 1 hit
PIRSFiPIRSF002155 Ribosomal_L1, 1 hit
SUPFAMiSSF56808 SSF56808, 1 hit
TIGRFAMsiTIGR01169 rplA_bact, 1 hit
PROSITEiView protein in PROSITE
PS01199 RIBOSOMAL_L1, 1 hit

Sequencei

Sequence statusi: Complete.

Q9ZK21-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKKVFKRLE KLFSKIQNDK VYGVEHGVEV VKSLASAKFD ETVEVALRLG
60 70 80 90 100
VDPRHADQMV RGAVVLLHGT GKKVRVAVFA KDIKQDEAKN AGADVVGGDD
110 120 130 140 150
LAEEIKNGRI DFDMVIATPD MMAVVGKVGR ILGPKGLMPN PKTGTVTMDI
160 170 180 190 200
AKAVTNAKSG QVNFRVDKKG NVHAPIGKAS FPEEKIKENM LELVKTINRL
210 220 230
KPSSAKGKYI RNAALSLTMS PSVNLDAQEL MDIK
Length:234
Mass (Da):25,361
Last modified:May 1, 1999 - v1
Checksum:i14C77CFC1483A2A4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE001439 Genomic DNA Translation: AAD06702.1
PIRiE71846
RefSeqiWP_001085856.1, NC_000921.1

Genome annotation databases

EnsemblBacteriaiAAD06702; AAD06702; jhp_1124
KEGGihpj:jhp_1124

Similar proteinsi

Entry informationi

Entry nameiRL1_HELPJ
AccessioniPrimary (citable) accession number: Q9ZK21
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: May 1, 1999
Last modified: May 23, 2018
This is version 104 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families
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