Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q9ZJ94

- GLMS_HELPJ

UniProt

Q9ZJ94 - GLMS_HELPJ

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

Gene

glmS

Organism
Helicobacter pylori (strain J99 / ATCC 700824) (Campylobacter pylori J99)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.UniRule annotation

Catalytic activityi

L-glutamine + D-fructose 6-phosphate = L-glutamate + D-glucosamine 6-phosphate.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei2 – 21Nucleophile; for GATase activityUniRule annotation
Active sitei592 – 5921For Fru-6P isomerization activityUniRule annotation

GO - Molecular functioni

  1. carbohydrate binding Source: InterPro
  2. glutamine-fructose-6-phosphate transaminase (isomerizing) activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbohydrate biosynthetic process Source: InterPro
  2. glutamine metabolic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminotransferase, Transferase

Enzyme and pathway databases

BioCyciHPYL85963:GJB9-1460-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]UniRule annotation (EC:2.6.1.16UniRule annotation)
Alternative name(s):
D-fructose-6-phosphate amidotransferaseUniRule annotation
GFATUniRule annotation
Glucosamine-6-phosphate synthaseUniRule annotation
Hexosephosphate aminotransferaseUniRule annotation
L-glutamine--D-fructose-6-phosphate amidotransferaseUniRule annotation
Gene namesi
Name:glmSUniRule annotation
Ordered Locus Names:jhp_1420
OrganismiHelicobacter pylori (strain J99 / ATCC 700824) (Campylobacter pylori J99)
Taxonomic identifieri85963 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter
ProteomesiUP000000804: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11RemovedUniRule annotation
Chaini2 – 597596Glutamine--fructose-6-phosphate aminotransferase [isomerizing]PRO_0000135341Add
BLAST

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Protein-protein interaction databases

STRINGi85963.jhp1420.

Structurei

3D structure databases

ProteinModelPortaliQ9ZJ94.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini2 – 218217Glutamine amidotransferase type-2UniRule annotationAdd
BLAST
Domaini276 – 416141SIS 1UniRule annotationAdd
BLAST
Domaini449 – 587139SIS 2UniRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 glutamine amidotransferase type-2 domain.UniRule annotation
Contains 2 SIS domains.UniRule annotation

Keywords - Domaini

Glutamine amidotransferase, Repeat

Phylogenomic databases

eggNOGiCOG0449.
KOiK00820.
OMAiGHKHTLA.
OrthoDBiEOG6KT2Q1.

Family and domain databases

Gene3Di3.60.20.10. 1 hit.
HAMAPiMF_00164. GlmS.
InterProiIPR017932. GATase_2_dom.
IPR005855. GlmS_trans.
IPR029055. Ntn_hydrolases_N.
IPR001347. SIS.
[Graphical view]
PANTHERiPTHR10937:SF0. PTHR10937:SF0. 1 hit.
PfamiPF01380. SIS. 2 hits.
[Graphical view]
SUPFAMiSSF56235. SSF56235. 1 hit.
TIGRFAMsiTIGR01135. glmS. 1 hit.
PROSITEiPS51278. GATASE_TYPE_2. 1 hit.
PS51464. SIS. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9ZJ94-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MCGIVGYIGD SEKKSILLEG LKELEYRGYD SAGLAVLSAN RLEVFKTQGK
60 70 80 90 100
LENLRTELKN KEFLNFGVSI AHTRWATHGK PSSANAHPHF TENLALVHNG
110 120 130 140 150
IIENYASLKK ELENKGHAFL SQTDTEVIAH LLEETLKSEG DLLKAFEKSI
160 170 180 190 200
SLLKGSYAIL MLHKRAKESL FYAKSSSPLI VGKGKEGVFF ASSLSVLAPK
210 220 230 240 250
VDQFVILEEN SVGQISLENF KDLNNIENMK DYAFENKDYS KGNFRNYLEK
260 270 280 290 300
EIYEQHSSLL ECLEGRLEAL SVYCEIDPEF LENVSEITLC SCGSSYHASL
310 320 330 340 350
ASVYLFERLA KIRARAILAS EYRYAHFKSN PNELFIAISQ SGETADTLEA
360 370 380 390 400
LKLAKAQGLK TISLCNAPFS MMSRISDHTL LIRAGVERSV ASTKAFSSQV
410 420 430 440 450
MLLWLLSVYL GKQLGTISKE EERIQAKNML NSVKAMKVEP KLHEKIKRLS
460 470 480 490 500
KRYLHGHGFF YIGRDVFYPL ALEGALKLKE ISYLHAEGYA SAEMKHGPIA
510 520 530 540 550
LVDSNLFTIA LLSKHLLFDK TKSNIEELSA RDSTICVLSS EILEIADDFI
560 570 580 590
QLEESESYME EFFRMNLAMQ LLALEIAMRL NHDVDHPRNL AKSVTVE
Length:597
Mass (Da):67,058
Last modified:January 23, 2007 - v3
Checksum:i663A81AC03C78C10
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE001439 Genomic DNA. Translation: AAD06999.1.
PIRiH71809.
RefSeqiNP_224138.1. NC_000921.1.
WP_000334347.1. NC_000921.1.

Genome annotation databases

EnsemblBacteriaiAAD06999; AAD06999; jhp_1420.
GeneIDi889462.
KEGGihpj:jhp1420.
PATRICi20607730. VBIHelPyl98156_1543.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE001439 Genomic DNA. Translation: AAD06999.1 .
PIRi H71809.
RefSeqi NP_224138.1. NC_000921.1.
WP_000334347.1. NC_000921.1.

3D structure databases

ProteinModelPortali Q9ZJ94.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 85963.jhp1420.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAD06999 ; AAD06999 ; jhp_1420 .
GeneIDi 889462.
KEGGi hpj:jhp1420.
PATRICi 20607730. VBIHelPyl98156_1543.

Phylogenomic databases

eggNOGi COG0449.
KOi K00820.
OMAi GHKHTLA.
OrthoDBi EOG6KT2Q1.

Enzyme and pathway databases

BioCyci HPYL85963:GJB9-1460-MONOMER.

Family and domain databases

Gene3Di 3.60.20.10. 1 hit.
HAMAPi MF_00164. GlmS.
InterProi IPR017932. GATase_2_dom.
IPR005855. GlmS_trans.
IPR029055. Ntn_hydrolases_N.
IPR001347. SIS.
[Graphical view ]
PANTHERi PTHR10937:SF0. PTHR10937:SF0. 1 hit.
Pfami PF01380. SIS. 2 hits.
[Graphical view ]
SUPFAMi SSF56235. SSF56235. 1 hit.
TIGRFAMsi TIGR01135. glmS. 1 hit.
PROSITEi PS51278. GATASE_TYPE_2. 1 hit.
PS51464. SIS. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: J99 / ATCC 700824.

Entry informationi

Entry nameiGLMS_HELPJ
AccessioniPrimary (citable) accession number: Q9ZJ94
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: January 23, 2007
Last modified: October 29, 2014
This is version 99 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3