Q9ZJ12 (YJEA_SALTY) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized protein YjeA

Gene names

Name:	yjeA
Synonyms:	genX
Ordered Locus Names:	STM4344

Organism

Salmonella typhimurium

Taxonomic identifier

90371 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Salmonella

Protein attributes

Sequence length	325 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Disruption phenotype	Mutants have a reduced pyruvate oxidase activity and a reduced growth rate. Ref.1
Sequence similarities	Belongs to the class-II aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Technical term	3D-structure Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	lysyl-tRNA aminoacylation Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: InterPro lysine-tRNA ligase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 325

325

Uncharacterized protein YjeA HAMAP MF_00174

PRO_0000152728

Experimental info

Sequence conflict

31

1

A → G in AAC82540. Ref.1

Sequence conflict

86

1

A → E in AAC82540. Ref.1

Sequence conflict

158

1

E → G in AAC82540. Ref.1

Sequence conflict

275

1

P → A in AAC82540. Ref.1

Sequence conflict

279

1

I → M in AAC82540. Ref.1

Secondary structure

1

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325

Helix Strand Turn

Details...

Helix

13 – 32

20

Beta strand

42 – 46

5

Beta strand

57 – 59

3

Beta strand

70 – 73

4

Helix

78 – 86

9

Beta strand

92 – 99

8

Beta strand

110 – 120

11

Helix

124 – 139

16

Beta strand

145 – 148

4

Helix

149 – 157

9

Turn

161 – 163

3

Helix

166 – 175

10

Helix

179 – 184

6

Helix

188 – 197

10

Beta strand

210 – 213

4

Helix

217 – 219

3

Beta strand

232 – 234

3

Beta strand

236 – 239

4

Beta strand

244 – 247

4

Helix

255 – 271

17

Helix

281 – 288

8

Beta strand

297 – 299

3

Helix

302 – 308

7

Helix

314 – 316

3

Beta strand

318 – 320

3

Turn

322 – 324

3

Sequences

	Sequence		Length	Mass (Da)
	Q9ZJ12 [UniParc]. Last modified January 23, 2002. Version 2. Checksum: E90A3109EE388E4C	FASTA	325	36,856
	10 20 30 40 50 60 MSETATWQPS ASIPNLLKRA AIMAEIRRFF ADRGVLEVET PCMSQATVTD IHLFPFETRF 70 80 90 100 110 120 VGPGHSQGIN LYLMTSPEYH MKRLLAAGCG PVFQLCRSFR NEEMGRHHNP EFTMLEWYRP 130 140 150 160 170 180 HYDMYRLMNE VDDLLQQVLD CQPAESLSYQ QAFQRHLEID PLSADKTQLR EAAAKLDLSN 190 200 210 220 230 240 IADTEEDRDT LLQLLFTMGV EPHIGKEKPT FIYHFPASQA SLAQISTEDH RVAERFEVYY 250 260 270 280 290 300 KGIELANGFH ELTDAREQQQ RFEQDNRKRA ARGLPQQPID QNLLDALAAG LPDCSGVALG 310 320 VDRLVMLALG AESLADVIAF TVDRA

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Molecular and functional characterization of Salmonella enterica serovar typhimurium poxA gene: effect on attenuation of virulence and protection." Kaniga K., Compton M.S., Curtiss R. III, Sundaram P. Infect. Immun. 66:5599-5606(1998) [PubMed: 9826331] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], DISRUPTION PHENOTYPE. Strain: UK-1.
[2]	"Complete genome sequence of Salmonella enterica serovar Typhimurium LT2." McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P., Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D., Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E. , Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R., Wilson R.K. Nature 413:852-856(2001) [PubMed: 11677609] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: LT2 / SGSC1412 / ATCC 700720.
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AF001831 Genomic DNA. Translation: AAC82540.1.
AE006468 Genomic DNA. Translation: AAL23167.1.

RefSeq

NP_463208.1. NC_003197.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
3G1Z	X-ray	1.95	A/B	1-325	[»]

ProteinModelPortal

Q9ZJ12.

ModBase

Search...

Proteomic databases

PRIDE

Q9ZJ12.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

GeneID

1255870.

GenomeReviews

Gene locus STM4344 in contig AE006468_GR.

KEGG

stm:STM4344.

NMPDR

fig|99287.1.peg.4181.

PATRIC

32387609. VBISalEnt20916_4571.

Phylogenomic databases

HOGENOM

HBG631383.

OMA

MPEASGI.

ProtClustDB

PRK09350.

Enzyme and pathway databases

BioCyc

STYP99287:STM4344-MONOMER.

Family and domain databases

HAMAP

MF_00174. YjeA.
[Tree]

InterPro

IPR004364. aa-tRNA-synt_II.
IPR018150. aa-tRNA-synt_II-like.
IPR006195. aa-tRNA-synth_II.
IPR004525. Lys-tRNA-synth-rel.
IPR018149. Lys-tRNA-synth_II_C.
[Graphical view]

KO

K04568.

PANTHER

PTHR22594. aa-tRNA-synt_II. 1 hit.
PTHR22594:SF7. PTHR22594:SF7. 1 hit.

Pfam

PF00152. tRNA-synt_2. 1 hit.
[Graphical view]

PRINTS

PR00982. TRNASYNTHLYS.

TIGRFAMs

TIGR00462. GenX. 1 hit.

PROSITE

PS50862. AA_TRNA_LIGASE_II. 1 hit.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

YJEA_SALTY

Accession

Primary (citable) accession number: Q9ZJ12

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 1, 2000
Last sequence update:	January 23, 2002
Last modified:	January 25, 2012
This is version 80 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program