Reviewed, UniProtKB/Swiss-Prot Q9ZIY0 (SYK3_HAEGA)

Names and origin

Protein names

Recommended name:
    Putative lysyl-tRNA synthetase
    EC=6.1.1.6
Alternative name(s):
    Lysine--tRNA ligase
      Short name=LysRS
    GX

Gene names

Name:	poxA
Synonyms:	genX

Organism

Haemophilus gallinarum

Taxonomic identifier

728 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Avibacterium

Protein attributes

Sequence length	322 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Could be a lysyl-tRNA synthetase. HAMAP MF_00174
Catalytic activity	ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys). HAMAP MF_00174
Sequence similarities	Belongs to the class-II aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Gene Ontology (GO)
Biological process	lysyl-tRNA aminoacylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP lysine-tRNA ligase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 322	322	Putative lysyl-tRNA synthetase HAMAP MF_00174		PRO_0000152723

Sequences

	Sequence		Length	Mass (Da)
	Q9ZIY0-1 [UniParc]. Last modified May 1, 1999. Version 1. Checksum: 035FE11A1B856025	FASTA	322	36,924
	10 20 30 40 50 60 MSEHQWKPTA SIQTLLSRAK IIAEIRQFFS ERGLLEVETP ILSEFGVTDV HLSTFSTKLI 70 80 90 100 110 120 SPFQKKEKTL WLSTSPEYPM KRLLSAGSGA IFQLCKVFRN EEAGKKHSPE FTMLEWYRPY 130 140 150 160 170 180 FDMYRLINEV DDLLQYILDC EPAESMSYQF AFQEYVGIDP LSASQDKLIE KAKEYCLENA 190 200 210 220 230 240 EREDRDTLLQ FLFNVAVESQ IGKDKPVAIY HFPATQAALA QISSEDHRVA ERFEFYYKGL 250 260 270 280 290 300 ELANGFCELT DANEQRHRFE QDNKQRERLG LPIHQIDERF LAALKAGVPN CSGVALGVDR 310 320 LIMIALGLEN INEVIAFSIE NA

References

[1]	Wise A.G., Glisson J.R., Jackwood M.W. Submitted (MAY-1997) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: Tw-1.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AF005272 Genomic DNA. Translation: AAD01242.1.
3D structure databases
HSSP	HSSP built from PDB template 1E1O based on UniProtKB P14825.
ModBase	Search...
Enzyme and pathway databases
BRENDA	6.1.1.6. 2318.
Family and domain databases
HAMAP	MF_00174. [Tree]
InterPro	IPR004364. aa-tRNA-synt_II. IPR018150. aa-tRNA-synt_II-like. IPR006195. aa-tRNA-synth_II_cons-reg. IPR004525. Lys-tRNA-synth-rel. IPR018149. Lys-tRNA-synth_II_C. [Graphical view]
PANTHER	PTHR22594. aa-tRNA-synt_II. 1 hit.
Pfam	PF00152. tRNA-synt_2. 1 hit. [Graphical view]
PRINTS	PR00982. TRNASYNTHLYS.
TIGRFAMs	TIGR00462. genX. 1 hit.
PROSITE	PS50862. AA_TRNA_LIGASE_II. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYK3_HAEGA

Accession

Primary (citable) accession number: Q9ZIY0

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 1, 2000
Last sequence update:	May 1, 1999
Last modified:	March 3, 2009
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)