SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q9ZHE5

- HIS8_BUCAP

UniProt

Q9ZHE5 - HIS8_BUCAP

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Histidinol-phosphate aminotransferase

Gene
hisC, BUsg_094
Organism
Buchnera aphidicola subsp. Schizaphis graminum (strain Sg)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

L-histidinol phosphate + 2-oxoglutarate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate.UniRule annotation

Cofactori

Pyridoxal phosphate By similarity.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. histidinol-phosphate transaminase activity Source: UniProtKB-HAMAP
  2. L-phenylalanine:2-oxoglutarate aminotransferase activity Source: UniProtKB-EC
  3. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. histidine biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminotransferase, Transferase

Keywords - Biological processi

Amino-acid biosynthesis, Histidine biosynthesis

Keywords - Ligandi

Pyridoxal phosphate

Enzyme and pathway databases

BioCyciBAPH198804:GHMG-103-MONOMER.
UniPathwayiUPA00031; UER00012.

Names & Taxonomyi

Protein namesi
Recommended name:
Histidinol-phosphate aminotransferase (EC:2.6.1.9)
Alternative name(s):
Imidazole acetol-phosphate transaminase
Gene namesi
Name:hisC
Ordered Locus Names:BUsg_094
OrganismiBuchnera aphidicola subsp. Schizaphis graminum (strain Sg)
Taxonomic identifieri198804 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera
ProteomesiUP000000416: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 355355Histidinol-phosphate aminotransferaseUniRule annotationPRO_0000153333Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei214 – 2141N6-(pyridoxal phosphate)lysine By similarity

Proteomic databases

PRIDEiQ9ZHE5.

Interactioni

Subunit structurei

Homodimer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi198804.BUsg094.

Structurei

3D structure databases

ProteinModelPortaliQ9ZHE5.
SMRiQ9ZHE5. Positions 2-353.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0079.
KOiK00817.
OMAiRYECERV.
OrthoDBiEOG651SWW.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
HAMAPiMF_01023. HisC_aminotrans_2.
InterProiIPR001917. Aminotrans_II_pyridoxalP_BS.
IPR004839. Aminotransferase_I/II.
IPR005861. HisP_aminotrans.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PfamiPF00155. Aminotran_1_2. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01141. hisC. 1 hit.
PROSITEiPS00599. AA_TRANSFER_CLASS_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9ZHE5-1 [UniParc]FASTAAdd to Basket

« Hide

MTANINKLAR KNIQKLNPYQ SARRIGGKGD TWLNANESPI SVPFKGKVKV    50
FNRYPECQPN NLLSSYANYV GLLNNQILVT RGADEGIELL IKAFCEPGKD 100
AIIYCPPTYD MYAINAKIAN VEIKEIPTFK NTWKIDLLNI RSNLNKVKLI 150
YICNPNNPTG NIVSQEDLKS LLKVTLGQSL VIIDEAYIEF SPKNSMVNYL 200
KTFPNLIILR TLSKAFALAG IRCGFTLAQK EVIDILHKVI SPYPISTLIA 250
DIAVQSLEKK AIDDMKNRVL KLNMNRIWLI DELKKISCVK KVFDSHANYI 300
LVEFYMFKKI FQSLWQKGII LRNQNHKNNL KNCLRISIGS KSECMRLVQE 350
LKNFI 355
Length:355
Mass (Da):40,474
Last modified:May 1, 1999 - v1
Checksum:iC919301FE84D6DC8
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF067228 Genomic DNA. Translation: AAC97356.1.
AE013218 Genomic DNA. Translation: AAM67664.1.
RefSeqiNP_660453.1. NC_004061.1.
WP_011053630.1. NC_004061.1.

Genome annotation databases

EnsemblBacteriaiAAM67664; AAM67664; BUsg_094.
GeneIDi1005911.
KEGGibas:BUsg094.
PATRICi21246965. VBIBucAph100086_0097.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF067228 Genomic DNA. Translation: AAC97356.1 .
AE013218 Genomic DNA. Translation: AAM67664.1 .
RefSeqi NP_660453.1. NC_004061.1.
WP_011053630.1. NC_004061.1.

3D structure databases

ProteinModelPortali Q9ZHE5.
SMRi Q9ZHE5. Positions 2-353.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 198804.BUsg094.

Proteomic databases

PRIDEi Q9ZHE5.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAM67664 ; AAM67664 ; BUsg_094 .
GeneIDi 1005911.
KEGGi bas:BUsg094.
PATRICi 21246965. VBIBucAph100086_0097.

Phylogenomic databases

eggNOGi COG0079.
KOi K00817.
OMAi RYECERV.
OrthoDBi EOG651SWW.

Enzyme and pathway databases

UniPathwayi UPA00031 ; UER00012 .
BioCyci BAPH198804:GHMG-103-MONOMER.

Family and domain databases

Gene3Di 3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
HAMAPi MF_01023. HisC_aminotrans_2.
InterProi IPR001917. Aminotrans_II_pyridoxalP_BS.
IPR004839. Aminotransferase_I/II.
IPR005861. HisP_aminotrans.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view ]
Pfami PF00155. Aminotran_1_2. 1 hit.
[Graphical view ]
SUPFAMi SSF53383. SSF53383. 1 hit.
TIGRFAMsi TIGR01141. hisC. 1 hit.
PROSITEi PS00599. AA_TRANSFER_CLASS_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Buchnera aphidicola (Aphid endosymbiont) contains genes encoding enzymes of histidine biosynthesis."
    Clark M.A., Baumann L., Baumann P.
    Curr. Microbiol. 37:356-358(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Sg.

Entry informationi

Entry nameiHIS8_BUCAP
AccessioniPrimary (citable) accession number: Q9ZHE5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: May 1, 1999
Last modified: September 3, 2014
This is version 98 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Buchnera aphidicola (subsp. Schizaphis graminum)
    Buchnera aphidicola (subsp. Schizaphis graminum): entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi