Q9ZHD8 (DCD_BUCAP) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Deoxycytidine triphosphate deaminase
Short name=dCTP deaminase
EC=3.5.4.13

Gene names

Name:	dcd
Ordered Locus Names:	BUsg_101

Organism

Buchnera aphidicola subsp. Schizaphis graminum (strain Sg) [Complete proteome] [HAMAP]

Taxonomic identifier

198804 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Buchnera › Buchnera aphidicola › Buchnera aphidicola (Schizaphis graminum)

Protein attributes

Sequence length	193 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	dCTP + H2O = dUTP + NH3. HAMAP-Rule MF_00146
Pathway	Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP-Rule MF_00146
Sequence similarities	Belongs to the dCTP deaminase family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	dUMP biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway dUTP biosynthetic process Inferred from electronic annotation. Source: InterPro pyrimidine ribonucleotide biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular_function	dCTP deaminase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 193	193	Deoxycytidine triphosphate deaminase HAMAP-Rule MF_00146		PRO_0000155970

Sequences

	Sequence		Length	Mass (Da)
	Q9ZHD8 [UniParc]. Last modified May 1, 1999. Version 1. Checksum: 8E19D4580C7C55E8	FASTA	193	21,871
	10 20 30 40 50 60 MRLSDTDIEE WLSKKKLVIQ PYPKKQLING ITVDIHLGNK FRFFYDHTTS CIDLSGSKEK 70 80 90 100 110 120 IALDLNKIVS CETIFSKKEP FFLKPGALAL FSTLENITLP NNLVGWLDGR SSLARLGLMV 130 140 150 160 170 180 HVTSHRIDPG WHGNIVLEFF NAGKLTLVLT PGIKIAALSF ELLSKPVLRP YNSRNESKYK 190 RQNGVVPSRI YEE

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Buchnera aphidicola (Aphid endosymbiont) contains genes encoding enzymes of histidine biosynthesis." Clark M.A., Baumann L., Baumann P. Curr. Microbiol. 37:356-358(1998) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"50 million years of genomic stasis in endosymbiotic bacteria." Tamas I., Klasson L., Canbaeck B., Naeslund A.K., Eriksson A.-S., Wernegreen J.J., Sandstroem J.P., Moran N.A., Andersson S.G.E. Science 296:2376-2379(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Sg.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF067228 Genomic DNA. Translation: AAC97363.1. AE013218 Genomic DNA. Translation: AAM67671.1.
RefSeq	NP_660460.1. NC_004061.1.
3D structure databases
ProteinModelPortal	Q9ZHD8.
SMR	Q9ZHD8. Positions 1-190.
ModBase	Search...
Protein-protein interaction databases
STRING	198804.BUsg101.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAM67671; AAM67671; BUsg_101.
GeneID	1005918.
KEGG	bas:BUsg101.
PATRIC	21246979. VBIBucAph100086_0104.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0717.
KO	K01494.
OMA	RQDAKYK.
ProtClustDB	PRK00416.
Enzyme and pathway databases
BioCyc	BAPH198804:GHMG-172-MONOMER.
UniPathway	UPA00610; UER00665.
Family and domain databases
HAMAP	MF_00146. dCTP_deaminase.
InterPro	IPR011962. dCTP_deam. IPR008180. dUTP_pyroPase. [Graphical view]
Pfam	PF00692. dUTPase. 1 hit. [Graphical view]
TIGRFAMs	TIGR02274. dCTP_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DCD_BUCAP

Accession

Primary (citable) accession number: Q9ZHD8

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 1, 2000
Last sequence update:	May 1, 1999
Last modified:	May 1, 2013
This is version 77 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program