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Q9ZH77 (MASY_STRC2) Reviewed, UniProtKB/Swiss-Prot

Last modified April 3, 2013. Version 60. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Protein attributes

Sequence length541 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Acetyl-CoA + H2O + glyoxylate = (S)-malate + CoA.

Pathway

Carbohydrate metabolism; glyoxylate cycle; (S)-malate from isocitrate: step 2/2.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the malate synthase family.

Ontologies

Keywords
   Biological processGlyoxylate bypass
Tricarboxylic acid cycle
   Cellular componentCytoplasm
   Molecular functionTransferase
Gene Ontology (GO)
   Biological_processglyoxylate cycle

Inferred from electronic annotation. Source: UniProtKB-UniPathway

tricarboxylic acid cycle

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionmalate synthase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 541541Malate synthase
PRO_0000166878

Sites

Active site1691Proton acceptor By similarity
Active site4541Proton donor By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9ZH77 [UniParc].

Last modified May 1, 1999. Version 1.
Checksum: 26206E19BB4B8395

FASTA54160,012
        10         20         30         40         50         60 
MSASAPSRPA VVTAPAVPRQ DEVLTEAALV FLAELHRRFT PRRDELLARR ARRRAEISRT 

        70         80         90        100        110        120 
GTLDFLPETA HVRADDSWRV APAPPALQDR RVEITGPADR RMTVNALNSG ARVWLADFED 

       130        140        150        160        170        180 
SSAPTWENVI SGQLALSDAY HRRIDFTDER SGKSYALRPD AELATVVMRP RGWHLPERHL 

       190        200        210        220        230        240 
TGPDGGVLPG ALVDFGLCFF HTARRLLDLG KGPYFYLPKL ESHQEARLWN DIFLFAQEQL 

       250        260        270        280        290        300 
GIPRGTIRAT VLIETITAAY EMEEILYELR EHASGLNAGR WDYLFSIIKN FRDAGPGFVL 

       310        320        330        340        350        360 
PDRNAITMTA PFMRAYTELL VRTCHRRGAH AIGGMAAFIP SRRDPEINRA AFEKVRADKD 

       370        380        390        400        410        420 
REAADGFDGS WVAHPDLVPV ALASFDAVLG DRPHQKDRLR EEVSVTAAEL IAVGSPAARP 

       430        440        450        460        470        480 
TAAGLLNAVR VGIRYIEAWL RGTGAVAIFH LMEDAATAEI SRSQIWQWIN AGVVLENGER 

       490        500        510        520        530        540 
VTPALVRTLA AGELGALRET LGGEEYAAGR WQEAHDLLLR VALDEEYADF LTLPAYERLT 


G

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References

[1]"Malate synthase from Streptomyces clavuligerus NRRL3585: cloning, molecular characterization and its control by acetate."
Chan M., Sim T.S.
Microbiology 144:3229-3237(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 27064 / DSM 738 / JCM 4710 / NBRC 13307 / NCIMB 12785 / NRRL 3585 / VKM Ac-602.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AF070989 Genomic DNA. Translation: AAC83648.1.

3D structure databases

ProteinModelPortalQ9ZH77.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

PATRIC29744904. VBIStrCla15562_1804.

Enzyme and pathway databases

BRENDA2.3.3.9. 5988.
UniPathwayUPA00703; UER00720.

Family and domain databases

InterProIPR011076. Malate_synth-like.
IPR006252. Malate_synthA.
IPR001465. Malate_synthase.
IPR019830. Malate_synthase_CS.
[Graphical view]
PANTHERPTHR21631:SF1. PTHR21631:SF1. 1 hit.
PfamPF01274. Malate_synthase. 1 hit.
[Graphical view]
PIRSFPIRSF001363. Malate_synth. 1 hit.
SUPFAMSSF51645. Malat_synth_like. 1 hit.
TIGRFAMsTIGR01344. malate_syn_A. 1 hit.
PROSITEPS00510. MALATE_SYNTHASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameMASY_STRC2
AccessionPrimary (citable) accession number: Q9ZH77
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: May 1, 1999
Last modified: April 3, 2013
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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